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  • Open Access

    ARTICLE

    Finite Element Analysis for Magneto-Convection Heat Transfer Performance in Vertical Wavy Surface Enclosure: Fin Size Impact

    Md. Fayz-Al-Asad1,4, F. Mebarek-Oudina2,*, H. Vaidya3, Md. Shamim Hasan4, Md. Manirul Alam Sarker4, A. I. Ismail5

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 817-837, 2024, DOI:10.32604/fhmt.2024.050814

    Abstract The goal of this paper is to represent a numerical study of magnetohydrodynamic mixed convection heat transfer in a lid-driven vertical wavy enclosure with a fin attached to the bottom wall. We use a finite element method based on Galerkin weighted residual (GWR) techniques to set up the appropriate governing equations for the present flow model. We have conducted a parametric investigation to examine the impact of Hartmann and Richardson numbers on the flow pattern and heat transmission features inside a wavy cavity. We graphically represent the numerical results, such as isotherms, streamlines, velocity profiles,… More >

  • Open Access

    ARTICLE

    Solar Radiation Estimation Based on a New Combined Approach of Artificial Neural Networks (ANN) and Genetic Algorithms (GA) in South Algeria

    Djeldjli Halima1,*, Benatiallah Djelloul1, Ghasri Mehdi2, Tanougast Camel3, Benatiallah Ali4, Benabdelkrim Bouchra1

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4725-4740, 2024, DOI:10.32604/cmc.2024.051002

    Abstract When designing solar systems and assessing the effectiveness of their many uses, estimating sun irradiance is a crucial first step. This study examined three approaches (ANN, GA-ANN, and ANFIS) for estimating daily global solar radiation (GSR) in the south of Algeria: Adrar, Ouargla, and Bechar. The proposed hybrid GA-ANN model, based on genetic algorithm-based optimization, was developed to improve the ANN model. The GA-ANN and ANFIS models performed better than the standalone ANN-based model, with GA-ANN being better suited for forecasting in all sites, and it performed the best with the best values in the… More > Graphic Abstract

    Solar Radiation Estimation Based on a New Combined Approach of Artificial Neural Networks (ANN) and Genetic Algorithms (GA) in South Algeria

  • Open Access

    ARTICLE

    Optimization Study of Active-Passive Heating System Parameters in Village Houses in the Southern Xinjiang Province

    Xiaodan Wu1, Jie Li1,*, Yongbin Cai2, Sihui Huang1

    Energy Engineering, Vol.121, No.7, pp. 1963-1990, 2024, DOI:10.32604/ee.2024.048477

    Abstract Aiming at the problems of large energy consumption and serious pollution of winter heating existing in the rural buildings in Southern Xinjiang, a combined active-passive heating system was proposed, and the simulation software was used to optimize the parameters of the system, according to the parameters obtained from the optimization, a test platform was built and winter heating test was carried out. The simulation results showed that the thickness of the air layer of 75 mm, the total area of the vent holes of 0.24 m, and the thickness of the insulation layer of 120… More >

  • Open Access

    ARTICLE

    Three Combined Treatments, a Novel HDAC Inhibitor OBP-801/YM753, 5-Fluorouracil, and Paclitaxel, Induce G2 Phase Arrest Through the p38 Pathway in Human Ovarian Cancer Cells

    Makoto Akiyama*†, Yoshihiro Sowa*, Tomoyuki Taniguchi*, Motoki Watanabe*, Shingo Yogosawa, Jo Kitawaki,Toshiyuki Sakai*

    Oncology Research, Vol.25, No.8, pp. 1245-1252, 2017, DOI:10.3727/096504017X14850164661097

    Abstract Ovarian cancer is the most lethal disease among gynecological malignancies. More effective therapy is required to counter high recurrence rates and chemotherapy resistance. We investigated the efficacy and molecular mechanisms of three combined treatments (TCTs)—a novel histone deacetylase (HDAC) inhibitor OBP-801/YM753, 5-fluorouracil (5-FU), and paclitaxel (PTX)—in human ovarian cancer SKOV-3 and OVCAR-3 cells. The inhibition of cell growth was stronger with TCTs than with each single agent and with two combined treatments. The TCTs significantly induce G2 phase arrest in both cell lines. We then analyzed the molecular mechanisms and found that the TCTs increased the More >

  • Open Access

    ARTICLE

    Preclinical evaluation of cyclophosphamide and fludarabine combined with CD19 CAR-T in the treatment of B-cell hematologic malignancies in vivo

    ZHIGANG XIA1,#, MENGYAO TIAN1,#, YUCAI CHENG1, WENFANG YI1, ZEFAN DU1,2, TIANWEN LI1,2, YUCHEN WEN1, LINDI LI1,2, YONG LIU1,2,*, CHUN CHEN1,*

    Oncology Research, Vol.32, No.6, pp. 1109-1118, 2024, DOI:10.32604/or.2024.049792

    Abstract Background: Chimeric antigen receptor T (CAR-T) cell therapy has achieved marked therapeutic success in ameliorating hematological malignancies. However, there is an extant void in the clinical guidelines concerning the most effective chemotherapy regimen prior to chimeric antigen receptor T (CAR-T) cell therapy, as well as the optimal timing for CAR-T cell infusion post-chemotherapy. Materials and Methods: We employed cell-derived tumor xenograft (CDX) murine models to delineate the optimal pre-conditioning chemotherapy regimen and timing for CAR-T cell treatment. Furthermore, transcriptome sequencing was implemented to identify the therapeutic targets and elucidate the underlying mechanisms governing the treatment regimen.… More >

  • Open Access

    ARTICLE

    Performance of Gas-Steam Combined Cycle Cogeneration Units Influenced by Heating Network Terminal Steam Parameters

    Guanglu Xie1, Zhimin Xue1, Bo Xiong1, Yaowen Huang1, Chaoming Chen1, Qing Liao1, Cheng Yang2,*, Xiaoqian Ma2

    Energy Engineering, Vol.121, No.6, pp. 1495-1519, 2024, DOI:10.32604/ee.2024.047832

    Abstract The determination of source-side extracted heating parameters is of great significance to the economic operation of cogeneration systems. This paper investigated the coupling performance of a cogeneration heating and power system multidimensionally based on the operating characteristics of the cogeneration units, the hydraulic and thermodynamic characteristics of the heating network, and the energy loads. Taking a steam network supported by a gas-steam combined cycle cogeneration system as the research case, the interaction effect among the source-side prime movers, the heating networks, and the terminal demand thermal parameters were investigated based on the designed values, the… More >

  • Open Access

    ARTICLE

    Path-Based Clustering Algorithm with High Scalability Using the Combined Behavior of Evolutionary Algorithms

    Leila Safari-Monjeghtapeh1, Mansour Esmaeilpour2,*

    Computer Systems Science and Engineering, Vol.48, No.3, pp. 705-721, 2024, DOI:10.32604/csse.2024.044892

    Abstract Path-based clustering algorithms typically generate clusters by optimizing a benchmark function. Most optimization methods in clustering algorithms often offer solutions close to the general optimal value. This study achieves the global optimum value for the criterion function in a shorter time using the minimax distance, Maximum Spanning Tree “MST”, and meta-heuristic algorithms, including Genetic Algorithm “GA” and Particle Swarm Optimization “PSO”. The Fast Path-based Clustering “FPC” algorithm proposed in this paper can find cluster centers correctly in most datasets and quickly perform clustering operations. The FPC does this operation using MST, the minimax distance, and… More >

  • Open Access

    ARTICLE

    Combined CNN-LSTM Deep Learning Algorithms for Recognizing Human Physical Activities in Large and Distributed Manners: A Recommendation System

    Ameni Ellouze1, Nesrine Kadri2, Alaa Alaerjan3,*, Mohamed Ksantini1

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 351-372, 2024, DOI:10.32604/cmc.2024.048061

    Abstract Recognizing human activity (HAR) from data in a smartphone sensor plays an important role in the field of health to prevent chronic diseases. Daily and weekly physical activities are recorded on the smartphone and tell the user whether he is moving well or not. Typically, smartphones and their associated sensing devices operate in distributed and unstable environments. Therefore, collecting their data and extracting useful information is a significant challenge. In this context, the aim of this paper is twofold: The first is to analyze human behavior based on the recognition of physical activities. Using the… More >

  • Open Access

    ARTICLE

    Combined Optimal Dispatch of Thermal Power Generators and Energy Storage Considering Thermal Power Deep Peak Clipping and Wind Energy Emission Grading Punishment

    Junhui Li1, Xuanzhong Luo1,2, Changxing Ge3, Cuiping Li1,*, Changrong Wang4

    Energy Engineering, Vol.121, No.4, pp. 869-893, 2024, DOI:10.32604/ee.2024.029722

    Abstract Peak load and wind energy emission pressure rise more as wind energy penetration keeps growing, which affects the stabilization of the PS (power system). This paper suggests integrated optimal dispatching of thermal power generators and BESS (battery energy storage system) taking wind energy emission grading punishment and deep peak clipping into consideration. Firstly, in order to minimize wind abandonment, a hierarchical wind abandonment penalty strategy based on fuzzy control is designed and introduced, and the optimal grid-connected power of wind energy is determined as a result of minimizing the peak cutting cost of the system.… More > Graphic Abstract

    Combined Optimal Dispatch of Thermal Power Generators and Energy Storage Considering Thermal Power Deep Peak Clipping and Wind Energy Emission Grading Punishment

  • Open Access

    ARTICLE

    MODELLING OF COMBINED HEAT AND MASS TRANSFER OF WATER DROPLETS IN THERMAL TECHNOLOGY EQUIPMENT

    Gintautas Miliauskas*, Stasys Sinkunas, Kristina Norvaisiene, Kestutis Sinkunas

    Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-6, 2012, DOI:10.5098/hmt.v3.2.3006

    Abstract Water droplet evaporation process is numerically modelled under various heat and mass transfer conditions. Regularities of heat transfer process interaction are examined. Modelling in this work was performed using the combined analytical – numerical method to investigate heat and mass transfer in the two-phase droplets-gas flow system. The influence of forced liquid circulation on the thermal state of droplets is taken into account by the effective coefficient of thermal conductivity. Calculating the rate of droplet evaporation and the intensity of convective heating, the influence of the Stefan’s hydrodynamic flow is taken into account. Balancing energy More >

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