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  • Open Access

    ARTICLE

    Preoperative Fasting of More Than 14 Hours Increases the Risk of Time-to-Death after Cardiothoracic Surgery in Children: A Retrospective Cohort Study

    Laortip Rattanapittayaporn, Maliwan Oofuvong*, Jutarat Tanasansuttiporn, Thavat Chanchayanon

    Congenital Heart Disease, Vol.18, No.1, pp. 23-39, 2023, DOI:10.32604/chd.2023.026026 - 09 January 2023

    Abstract Background: Prolonged preoperative fasting can cause hypoglycemia, hyperglycemia, and intravascular volume depletion in children. We aimed to examine whether prolonged preoperative fasting is associated with in-hospital mortality and other morbidities in pediatric cardiothoracic surgery. Methods: This retrospective cohort study included children aged 0–3 years who underwent cardiac surgery between July 2014 and October 2020. The patient demographic data, surgery-related and anesthesia-related factors, and postoperative outcomes, including hypoglycemia, hyperglycemia, sepsis, length of intensive care unit stay, and in-hospital mortality, were recorded. The main exposure and outcome variables were prolonged fasting and time-to-death after surgery, respectively. The associations between… More > Graphic Abstract

    Preoperative Fasting of More Than 14 Hours Increases the Risk of Time-to-Death after Cardiothoracic Surgery in Children: A Retrospective Cohort Study

  • Open Access

    ARTICLE

    Association between Self-Rated Health and Depressive Symptoms in Rural Chinese Adults: A Cohort Study Based on Propensity Score Matching

    Yang Wang1, Jinlong Lin1,*, M. James C. Crabbe2,3,4, Xiao-Guang Yue5

    International Journal of Mental Health Promotion, Vol.24, No.3, pp. 385-398, 2022, DOI:10.32604/ijmhp.2022.020664 - 17 March 2022

    Abstract Health status is widely regarded as a correlate of depressive symptoms. However, health assessments based on clinical diagnosis in rural areas with poor medical conditions are very limited. Self-rated health (SRH) serves as a simple and convenient evaluation indicator, which may be used as an independent predictor of depressive symptoms. To confirm the relationship between SRH and depressive symptoms in rural adults, a longitudinal survey of rural households in China was conducted using the China Family Panel Studies (CFPS) from 2012 to 2016. Propensity score matching and logistic regression analysis were used to explore the… More >

  • Open Access

    ARTICLE

    The Comprehensive Analysis of Efficacy and Safety of CalliSpheres® Drug-Eluting Beads Transarterial Chemoembolization in 367 Liver Cancer Patients: A Multiple-Center, Cohort Study

    Zhiyi Peng*1, Guohong Cao†1, Qinming Hou, Ling Li§, Shihong Ying*, Junhui Sun, Guanhui Zhou, Jian Zhou#, Xin Zhang*, Wenbin Ji**, Zhihai Yu††, Tiefeng Li‡‡, Dedong Zhu§, Wenhao Hu§§, Jiansong Ji¶¶, Haijun Du##, Changsheng Shi***, Xiaohua Guo†††, Jian Fang‡‡‡, Jun Han§§§, Wenjiang Gu¶¶¶, Xiaoxi Xie###, Zhichao Sun****, Huanhai Xu††††, Xia Wu‡‡‡‡, Tingyang Hu§§§§, Jing Huang¶¶¶¶, Hongjie Hu‡‡‡‡, Jiaping Zheng####, Jun Luo####, Yutang Chen####, Wenqiang Yu§§§§, Guoliang Shao####

    Oncology Research, Vol.28, No.3, pp. 249-271, 2020, DOI:10.3727/096504019X15766663541105

    Abstract This study aimed to investigate the efficacy, safety, and prognostic factors of drug-eluting beads transarterial chemoembolization (DEB-TACE) in treating Chinese patients with liver cancer. A total of 367 liver cancer patients from 24 medical centers were consecutively enrolled in this multiple-center, prospective cohort study, including 275 hepatocellular carcinoma (HCC) cases, 37 intrahepatic cholangiocarcinoma (ICC) cases, and 55 secondary liver cancer cases. All the patients received CalliSpheres® DEB-TACE treatment. Treatment response, overall survival (OS), change of liver function, and adverse events (AEs) were assessed. DEB-TACE treatment achieved 19.9% complete response (CR) and 79.6% objective response rate (ORR),… More >

  • Open Access

    ARTICLE

    Mid-Term Outcome of Surgical Treatment in Pediatric Patients with Ebstein’s Anomaly: A Single-Center Cohort Study

    Jiachen Li, Xianchao Jiang, Sim-eng Zhang, Jinyang Liu, Yajuan Zhang, Jun Yan, Shoujun Li, Qiang Wang*

    Congenital Heart Disease, Vol.15, No.5, pp. 387-397, 2020, DOI:10.32604/CHD.2020.013127 - 23 September 2020

    Abstract Background: Ebstein’s anomaly (EA) is a malformation of the tricuspid valve (TV) and myopathy of the right ventricle (RV). Surgery is now the main treatment for the defect. Objective: To summarize our surgical results and experience based on patients with EA who were under 7 years of age and treated with different surgical treatments. Design: Single-center cohort study of Ebstein’s anomaly. Setting: China. Participants: 80 patients under 7 years old who were diagnosed of EA and underwent different surgical treatments were consecutively enrolled in our research from January 2010 to December 2019. Results: The median age of the… More >

  • Open Access

    ARTICLE

    Comparison of Treatment Response and Survival Profiles Between Drug-Eluting Bead Transarterial Chemoembolization and Conventional Transarterial Chemoembolization in Chinese Hepatocellular Carcinoma Patients: A Prospective Cohort Study

    Ping Wen*, Sheng-Duo Chen*, Jia-Rui Wang, Ying-He Zeng*

    Oncology Research, Vol.27, No.5, pp. 583-592, 2019, DOI:10.3727/096504018X15368325811545

    Abstract This study evaluated the difference in treatment response and survival profiles between drug-eluting bead transarterial chemoembolization (DEB-TACE) and conventional transarterial chemoembolization (cTACE) treatments in Chinese hepatocellular carcinoma (HCC) patients. A total of 120 HCC patients were consecutively enrolled in this prospective cohort study, which showed that DEB-TACE achieved higher complete response (CR) (30.8%) compared with cTACE (7.4%) with no difference in overall response rate (ORR) for patients treated with DEB-TACE and cTACE (80.8% vs. 73.5%). In addition, DEB-TACE was associated with a lower rate of progressive disease (PD) compared with cTACE (1.9% vs. 11.8%). With… More >

  • Open Access

    ARTICLE

    Physical activity modulates arterial stiffness in children with congenital heart disease: A CHAMPS cohort study*

    Natasha G. Boyes1, Michael K. Stickland2, Stephanie Fusnik1, Elizabeth Hogeweide1, Josie T.J. Fries1, Mark J. Haykowsky3, Chantelle L. Baril1, Shonah Runalls1, Ashok Kakadekar4, Scott Pharis4, Charissa Pockett4, Timothy J. Bradley4, Kristi D. Wright5, Marta Erlandson1, Corey R. Tomczak1

    Congenital Heart Disease, Vol.13, No.4, pp. 578-583, 2018, DOI:10.1111/chd.12614

    Abstract Children with congenital heart disease are at risk for developing increased arterial stiffness and this may be modulated by physical activity. Objective: To compare arterial stiffness in high- and low-physically active children with congenital heart disease and healthy age- and sex-matched controls.
    Patients: Seventeen children with congenital heart disease (12 ± 2 years; females = 9), grouped by low- and high-physical activity levels from accelerometry step count values, and 20 matched controls (11 ± 3 years; females = 9) were studied.
    Outcome Measures: Carotid-radial pulse wave velocity was assessed with applanation tonometry to determine arterial stiffness. Body composition… More >

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