Nicholas Y. Tan1, Christine H. Attenhofer Jost1, Murray D. Polkinghorne1, Emily R. Vargas2, David O. Hodge2, Joseph A. Dearani3, Samuel J. Asirvatham1,4, Heidi M. Connolly1, Christopher J. McLeod1
Congenital Heart Disease, Vol.14, No.6, pp. 1157-1165, 2019, DOI:10.1111/chd.12841
Abstract Introduction: Mechanisms and risk factors for cerebrovascular accidents (CVAs) in
Ebstein’s anomaly (EA) are not well understood; hence, we aimed to clarify these in a
large cohort of EA patients.
Methods: Patients with a confirmed diagnosis of EA were retrospectively reviewed.
Baseline characteristics were compared between patients with and without a prior
history of CVA using logistic regression modeling. Cox regression analysis was used to
identify predictors of CVA following initial evaluation. CVA incidence from birth and
following tricuspid valve surgery were estimated using the Kaplan‐Meier method.
Results: Nine hundred sixty‐eight patients (median age 21.1 years, 41.5% male)… More >
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