Yanhuan Lin^1,#, Jiaxin Feng^2,#, Hao Fang², Wei Huang², Kanglie Guo², Xiyan Liu², Shuqi Wang², Xiaojuan Liu^2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.10, pp. 2583-2596, 2024, DOI:10.32604/phyton.2024.055616 - 30 October 2024

Abstract Heat shock transcription factor (HSF) are essential regulators of heat shock protein (HSP) gene expression in plants and algae, contributing to their resilience against biotic and abiotic stresses. However, the localization, structure, phylogenetic relationship, and characteristics of PtHSF genes in microalgae, especially in diatom Phaeodactylum tricornutum, remain largely unexplored. This study presents a comprehensive analysis of the PtHSF gene family in P. tricornutum. A genome-wide analysis identified 68 PtHSF genes, which were classified into two distinct subfamilies: traditional and untraditional. Motif and structure analyses revealed evidence of multiple duplication events within the PtHSF gene family. Expression profiling revealed diurnal… More >

LINGHUI YU^#, RONG SHEN^#, YANAN GUO, YANXUAN GUO, CHEN LI, YANFENG SONG^*, DEGUI WANG^*

BIOCELL, Vol.45, No.3, pp. 761-772, 2021, DOI:10.32604/biocell.2021.014602 - 03 March 2021

Abstract Various factors can induce cell degeneration by altering the phenotype and metabolism of cells. Mitochondria play an essential role in cellular homeostasis and function, rendering aging processes highly associated with mitochondrial function and status. Herein, we describe an aging-prone phenotype of murine skin cells caused by depletion of Rad6B (Ube2b), an E2 ubiquitin-conjugating enzyme. In this study, using Masson’s trichrome, we showed that loss of Rad6B causes physiological structure changes in mouse skin with age. In addition, a combination of western blotting experiments, transmission electron microscopy and employment of immunofluorescence staining revealed that depletion of More >

KAVITHA GOVARTHANAN^1,*, PIYUSH KUMAR GUPTA², BINITA ZIPPORAHE¹, REKHA GAHTORI³, SOUMYA PANDIT², RAM PRASAD^4,*

BIOCELL, Vol.45, No.3, pp. 501-515, 2021, DOI:10.32604/biocell.2021.014441 - 03 March 2021

Abstract Stem cells constitute the source of cells that replenishes the worn out or damaged cells in our tissue and enable the tissue to carry out the destined function. Tissue-specific stem cells are compartmentalized in a niche, which keeps the stem cells under quiescent condition. Thus, understanding the molecular events driving the successful differentiation of stem cells into several lineages is essential for its better manipulation of human applications. Given the developmental aspects of the cell, the cellular function is greatly dependent on the epigenomics signature that in turn governs the expression profile of the cell.… More >