Courtney C. Mitchell1, Brian K. Rivera1, Jennifer N. Cooper 2,4, Charles V. Smith3, Darren P. Berman4,5, Jonathan L. Slaughter1,4, Carl H. Backes1,4,5
Congenital Heart Disease, Vol.14, No.1, pp. 95-99, 2019, DOI:10.1111/chd.12704
Abstract The optimal treatment method for infants with a patent ductus arteriosus (PDA) necessitating closure remains a subject of controversy and debate. While the risks associated with surgical PDA ligation are well described, the available evidence base for
alternative management strategies during infancy, including percutaneous closure or
conservative (nonintervention) management, are not well explored. Among infants,
the goals of this review are to: (a) use rigorous systematic review methodology to assess the quality and quantity of published reports on percutaneous closure vs surgical ligation; (b) compare outcomes of percutaneous closure vs conservative
management; and (c) based More >