Juan Lizandro Rodríguez‐Hernández1, Fayna Rodríguez‐González2, Marta Riaño‐Ruiz3, Efrén Martínez‐Quintana1,4
Congenital Heart Disease, Vol.13, No.5, pp. 655-662, 2018, DOI:10.1111/chd.12620
Abstract Introduction: Hyperuricemia has been associated with cardiovascular risk factors but
it remains controversial if uric acid is an independent predictor of cardiac mortality.
Methods: A total of 503 CHD patients (457 nonhypoxemic and 46 hypoxemic) and
772 control patients fulfilled inclusion criteria. Demographic, clinical, and analytical
data [serum uric acid and 24h urine uric acid levels, N‐terminal pro‐B‐type natriuretic
peptide (NT‐pro‐BNP), and C‐reactive‐protein (CRP) concentrations] were studied.
Survivals curves to determine cardiac death and arterial thrombosis in CHD patients
were also examined.
Results: Noncyanotic and cyanotic CHD patients had significant higher serum uric
acid concentration (5.2 ± 1.5 vs 4.9 ± 1.3mg/dL,… More >
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