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    ARTICLE

    Classifying Cardiac Anomalies in Right and Left Isomerism: Concordant and Discordant Patterns

    Lilia Oreto1,*, Giuseppe Mandraffino2, Paolo Ciliberti3, Teresa P. Santangelo4, Placido Romeo5, Antonio Celona5, Placido Gitto1, Lorenzo Galletti3, Fiore S. Iorio3, Alfredo Di Pino1, Aurelio Secinaro4, Paolo Guccione3, Robert H. Anderson6, Salvatore Agati1

    Congenital Heart Disease, Vol.18, No.1, pp. 97-111, 2023, DOI:10.32604/chd.2022.023619 - 09 January 2023

    Abstract Aims: Evidence is emerging that, in the setting of isomerism, the atrial and bronchial arrangement are not always concordant, nor are these patterns always harmonious with the arrangement of the abdominal organs. We aimed to evaluate the concordance between these features in a cohort of patients with cardiac malformations in the setting of known isomerism, seeking to determine whether it was feasible to assess complexity on this basis, in this regard taking note of the potential value of bronchial as opposed to appendage morphology. Methods and Results: We studied 78 patients known to have isomerism of the… More > Graphic Abstract

    Classifying Cardiac Anomalies in Right and Left Isomerism: Concordant and Discordant Patterns

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