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  • Open Access

    REVIEW

    Renewable Polymers in Biomedical Applications: From the Bench to the Market

    Rauany Cristina Lopes1, Tamires Nossa2, Wilton Rogério Lustri1, Gabriel Lombardo3,4,5, Maria Inés Errea3,4, Eliane Trovatti1,*

    Journal of Renewable Materials, Vol.12, No.4, pp. 643-666, 2024, DOI:10.32604/jrm.2024.048957

    Abstract Polymers from renewable resources have been used for a long time in biomedical applications and found an irreplaceable role in some of them. Their uses have been increasing because of their attractive properties, contributing to the improvement of life quality, mainly in drug release systems and in regenerative medicine. Formulations using natural polymer, nano and microscale particles preparation, composites, blends and chemical modification strategies have been used to improve their properties for clinical application. Although many studies have been carried out with these natural polymers, the way to reach the market is long and only More >

  • Open Access

    REVIEW

    Development of micro/nanostructured‒based biomaterials with biomedical applications

    AFAF ALHARTHI*

    BIOCELL, Vol.47, No.8, pp. 1743-1755, 2023, DOI:10.32604/biocell.2023.027154

    Abstract Natural biomaterials are now frequently used to build biocarrier systems, which can carry medications and biomolecules to a target region and achieve a desired therapeutic effect. Biomaterials and polymers are of great importance in the synthesis of nanomaterials. The recent studies have tended to use these materials because they are easily obtained from natural sources such as fungi, algae, bacteria, and medicinal plants. They are also biodegradable, compatible with neighborhoods, and non-toxic. Natural biomaterials and polymers are chemically changed when they are linked by cross linking agents with other polymers to create scaffolds, matrices, composites, More >

  • Open Access

    ARTICLE

    Polymers from Renewable Resources: Perspectives in Biomedical Applications

    Andrea Morelli, Dario Puppi, Federica Chiellini*

    Journal of Renewable Materials, Vol.1, No.2, pp. 83-112, 2013, DOI:10.7569/JRM.2012.634106

    Abstract Polymers, particularly those susceptible to undergoing biodegradation under physiological environments, can be considered the materials of choice for biomedical applications such as tissue engineering, regenerative medicine, and controlled and targeted drug delivery. The development of these relatively new fi elds of biomedical research represents the driving force towards the exploitation of renewable resources for the obtainment of biobased polymeric biomaterials. This perspective article reports on the biomedical applications of three major categories of biobased polymeric materials obtained from renewable resources, namely, polysaccharides, proteins and polyesters of natural origins. Particular emphasis is given to biobased polymers More >

  • Open Access

    ARTICLE

    Fusion Based Tongue Color Image Analysis Model for Biomedical Applications

    Esam A. AlQaralleh1, Halah Nassif2, Bassam A. Y. Alqaralleh2,*

    CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 5477-5490, 2022, DOI:10.32604/cmc.2022.024364

    Abstract Tongue diagnosis is a novel and non-invasive approach commonly employed to carry out the supplementary diagnosis over the globe. Recently, several deep learning (DL) based tongue color image analysis models have existed in the literature for the effective detection of diseases. This paper presents a fusion of handcrafted with deep features based tongue color image analysis (FHDF-TCIA) technique to biomedical applications. The proposed FDHF-TCIA technique aims to investigate the tongue images using fusion model, and thereby determines the existence of disease. Primarily, the FHDF-TCIA technique comprises Gaussian filtering based preprocessing to eradicate the noise. The More >

  • Open Access

    ARTICLE

    The Identification of Elastic Moduli of a Stratified Layer Through Localized Surface Probes, with Biomedical Applications

    A.R.Skovoroda1, R.V.Goldstein2

    CMES-Computer Modeling in Engineering & Sciences, Vol.4, No.3&4, pp. 457-472, 2003, DOI:10.3970/cmes.2003.004.457

    Abstract We discuss the inverse problem of the recovery of the distribution of the elastic moduli of a stratified layer, based on measurements of the surface displacement under localized surface loads. A general parametric solution and a numerical procedure for computing the parameters are presented. Examples of numerical results are given. The problem and its solution are related to the monitoring of elastic properties of living tissues. More >

  • Open Access

    ARTICLE

    Structural Refinement of Titanium-Aluminum-Niobium Alloy for Biomedical Applications

    Joaquín E. González-Hernández1, Jorge M. Cubero-Sesin1,2*, Elena Ulate-Kolitsky1, Priscilla Navarro1, Stephen Petretti1, Zenji Horita3,4

    Journal of Renewable Materials, Vol.5, No.3-4, pp. 300-306, 2017, DOI:10.7569/JRM.2017.634120

    Abstract In this work, a modification of the microstructure of a commercial Ti-6Al-7Nb alloy was accomplished by high-pressure torsion (HPT) at room temperature, to produce a bulk nanostructure on discs of 10 mm diameter and ~0.8 mm thickness. The metallographic analyses of the discs were performed by optical microscopy and scanning electron microscopy with energy dispersive spectroscopy. The results confirmed the presence of aluminum (Al) and niobium (Nb) as the sole alloying elements, promoting a duplex (α + β) titanium (Ti) microstructure prior to HPT processing. After HPT processing, nanostructure refinement was attained, reflected in the More >

  • Open Access

    ARTICLE

    Functional Electrospun Poly (Lactic Acid) Scaffolds for Biomedical Applications: Experimental Conditions, Degradation and Biocompatibility Study

    Idalba A. Hidalgo A., Felipe Sojo, Francisco Arvelo, Marcos A. Sabino∗,‡

    Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 85-105, 2013, DOI:10.3970/mcb.2013.010.085

    Abstract The electrospinning technique is a method used to produce nano and microfibers using the influence of electrostatic forces. Porous three dimensional networks of continuous and interconnected fibers as scaffolds were obtained from a poly (lactic acid) solution. The concentration of the polymeric solution, 12.5% m/w, as well as the conditions of voltage (V=11kV) and tip-metallic collector distance (H=13cm) were established to develop these scaffolds through the electrospinning process. The characteristics of the scaffolds, such as fiber diameter, sintering and the biomimetics of the characteristics of a native extra cellular matrix were verified by Scanning Electron More >

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