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  • Open Access

    ARTICLE

    RoBGP: A Chinese Nested Biomedical Named Entity Recognition Model Based on RoBERTa and Global Pointer

    Xiaohui Cui1,2,#, Chao Song1,2,#, Dongmei Li1,2,*, Xiaolong Qu1,2, Jiao Long1,2, Yu Yang1,2, Hanchao Zhang3

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3603-3618, 2024, DOI:10.32604/cmc.2024.047321

    Abstract Named Entity Recognition (NER) stands as a fundamental task within the field of biomedical text mining, aiming to extract specific types of entities such as genes, proteins, and diseases from complex biomedical texts and categorize them into predefined entity types. This process can provide basic support for the automatic construction of knowledge bases. In contrast to general texts, biomedical texts frequently contain numerous nested entities and local dependencies among these entities, presenting significant challenges to prevailing NER models. To address these issues, we propose a novel Chinese nested biomedical NER model based on RoBERTa and Global Pointer (RoBGP). Our model… More >

  • Open Access

    ARTICLE

    Multimodality Medical Image Fusion Based on Pixel Significance with Edge-Preserving Processing for Clinical Applications

    Bhawna Goyal1, Ayush Dogra2, Dawa Chyophel Lepcha1, Rajesh Singh3, Hemant Sharma4, Ahmed Alkhayyat5, Manob Jyoti Saikia6,*

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4317-4342, 2024, DOI:10.32604/cmc.2024.047256

    Abstract Multimodal medical image fusion has attained immense popularity in recent years due to its robust technology for clinical diagnosis. It fuses multiple images into a single image to improve the quality of images by retaining significant information and aiding diagnostic practitioners in diagnosing and treating many diseases. However, recent image fusion techniques have encountered several challenges, including fusion artifacts, algorithm complexity, and high computing costs. To solve these problems, this study presents a novel medical image fusion strategy by combining the benefits of pixel significance with edge-preserving processing to achieve the best fusion performance. First, the method employs a cross-bilateral… More >

  • Open Access

    ARTICLE

    MICROCANTILEVERS IN BIOMEDICAL AND THERMO/FLUID APPLICATIONS

    Khalil Khanafera, Kambiz Vafaib,*

    Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-9, 2010, DOI:10.5098/hmt.v1.2.3004

    Abstract A study was conducted to demonstrate the applications of microcantilevers in biomedical and thermo/fluid fields. The deflection of the microcantilevers due to biomaterial and turbulence effects was highlighted in this work. The novel patented microcantilever assemblies that were presented in this study can increase the signal and decrease the unfavorable deflection due to flow disturbances. This work paves the road for researchers in the area microcantilever based biosensors to design efficient microsensor systems that exhibit minimal errors in the measurements. Fluid-structure interaction was also utilized to investigate some aspects of the fluid flow and heat transfer characteristics. More >

  • Open Access

    REVIEW

    Development of micro/nanostructured‒based biomaterials with biomedical applications

    AFAF ALHARTHI*

    BIOCELL, Vol.47, No.8, pp. 1743-1755, 2023, DOI:10.32604/biocell.2023.027154

    Abstract Natural biomaterials are now frequently used to build biocarrier systems, which can carry medications and biomolecules to a target region and achieve a desired therapeutic effect. Biomaterials and polymers are of great importance in the synthesis of nanomaterials. The recent studies have tended to use these materials because they are easily obtained from natural sources such as fungi, algae, bacteria, and medicinal plants. They are also biodegradable, compatible with neighborhoods, and non-toxic. Natural biomaterials and polymers are chemically changed when they are linked by cross linking agents with other polymers to create scaffolds, matrices, composites, and interpenetrating polymer networks employing… More >

  • Open Access

    ARTICLE

    Medical Image Fusion Based on Anisotropic Diffusion and Non-Subsampled Contourlet Transform

    Bhawna Goyal1,*, Ayush Dogra2, Rahul Khoond1, Dawa Chyophel Lepcha1, Vishal Goyal3, Steven L. Fernandes4

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 311-327, 2023, DOI:10.32604/cmc.2023.038398

    Abstract The synthesis of visual information from multiple medical imaging inputs to a single fused image without any loss of detail and distortion is known as multimodal medical image fusion. It improves the quality of biomedical images by preserving detailed features to advance the clinical utility of medical imaging meant for the analysis and treatment of medical disorders. This study develops a novel approach to fuse multimodal medical images utilizing anisotropic diffusion (AD) and non-subsampled contourlet transform (NSCT). First, the method employs anisotropic diffusion for decomposing input images to their base and detail layers to coarsely split two features of input… More >

  • Open Access

    ARTICLE

    An Optimal Framework for Alzheimer’s Disease Diagnosis

    Amer Alsaraira1,*, Samer Alabed1, Eyad Hamad1, Omar Saraereh2

    Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 165-177, 2023, DOI:10.32604/iasc.2023.036950

    Abstract Alzheimer’s disease (AD) is a kind of progressive dementia that is frequently accompanied by brain shrinkage. With the use of the morphological characteristics of MRI brain scans, this paper proposed a method for diagnosing moderate cognitive impairment (MCI) and AD. The anatomical features of 818 subjects were calculated using the FreeSurfer software, and the data were taken from the ADNI dataset. These features were first removed from the dataset after being preprocessed with an age correction algorithm using linear regression to estimate the effects of normal aging. With these preprocessed characteristics, the extreme learning machine served as a classifier for… More >

  • Open Access

    ARTICLE

    Automated Colonic Polyp Detection and Classification Enabled Northern Goshawk Optimization with Deep Learning

    Mohammed Jasim Mohammed Jasim1, Bzar Khidir Hussan2, Subhi R. M. Zeebaree3,*, Zainab Salih Ageed4

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3677-3693, 2023, DOI:10.32604/cmc.2023.037363

    Abstract The major mortality factor relevant to the intestinal tract is the growth of tumorous cells (polyps) in various parts. More specifically, colonic polyps have a high rate and are recognized as a precursor of colon cancer growth. Endoscopy is the conventional technique for detecting colon polyps, and considerable research has proved that automated diagnosis of image regions that might have polyps within the colon might be used to help experts for decreasing the polyp miss rate. The automated diagnosis of polyps in a computer-aided diagnosis (CAD) method is implemented using statistical analysis. Nowadays, Deep Learning, particularly through Convolution Neural networks… More >

  • Open Access

    ARTICLE

    Sequence-Based Predicting Bacterial Essential ncRNAs Algorithm by Machine Learning

    Yuan-Nong Ye1,2,3,*, Ding-Fa Liang2, Abraham Alemayehu Labena4, Zhu Zeng2,*

    Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 2731-2741, 2023, DOI:10.32604/iasc.2023.026761

    Abstract Essential ncRNA is a type of ncRNA which is indispensable for the survival of organisms. Although essential ncRNAs cannot encode proteins, they are as important as essential coding genes in biology. They have got wide variety of applications such as antimicrobial target discovery, minimal genome construction and evolution analysis. At present, the number of species required for the determination of essential ncRNAs in the whole genome scale is still very few due to the traditional methods are time-consuming, laborious and costly. In addition, traditional experimental methods are limited by the organisms as less than 1% of bacteria can be cultured… More >

  • Open Access

    ARTICLE

    Symbiotic Organisms Search with Deep Learning Driven Biomedical Osteosarcoma Detection and Classification

    Abdullah M. Basahel1, Mohammad Yamin1, Sulafah M. Basahel2, Mona M. Abusurrah3, K.Vijaya Kumar4, E. Laxmi Lydia5,*

    CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 133-148, 2023, DOI:10.32604/cmc.2023.031786

    Abstract Osteosarcoma is one of the rare bone cancers that affect the individuals aged between 10 and 30 and it incurs high death rate. Early diagnosis of osteosarcoma is essential to improve the survivability rate and treatment protocols. Traditional physical examination procedure is not only a time-consuming process, but it also primarily relies upon the expert’s knowledge. In this background, the recently developed Deep Learning (DL) models can be applied to perform decision making. At the same time, hyperparameter optimization of DL models also plays an important role in influencing overall classification performance. The current study introduces a novel Symbiotic Organisms… More >

  • Open Access

    ARTICLE

    IOT Assisted Biomedical Monitoring Sensors for Healthcare in Human

    S. Periyanayagi1, V. Nandini2,*, K. Basarikodi3, V. Sumathy4

    Computer Systems Science and Engineering, Vol.45, No.3, pp. 2853-2868, 2023, DOI:10.32604/csse.2023.030538

    Abstract The Internet of Things (IoT) is a concept that refers to the deployment of Internet Protocol (IP) address sensors in health care systems to monitor patients’ health. It has the ability to access the Internet and collect data from sensors. Automated decisions are made after evaluating the information of illness people records. Patients’ health and well-being can be monitored through IoT medical devices. It is possible to trace the origins of biological, medical equipment and processes. Human reliability is a major concern in user activity and fitness trackers in day-to-day activities. The fundamental challenge is to measure the efficiency of… More >

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