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  • Open Access

    ABSTRACT

    Computational Modeling of Human Bicuspid Pulmonary Valve Dynamic Deformation in Patients with Tetralogy of Fallot

    Caili Li1,§, Christopher Baird2, Jing Yao3, Chun Yang4, Liang Wang5, Han Yu5, Tal Geva6, Dalin Tang5,*,7,§

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 59-59, 2019, DOI:10.32604/mcb.2019.06872

    Abstract Pulmonary valve stenosis (PVS) is one common right ventricular outflow tract obstruction problem in patients with tetralogy of Fallot (TOF). Congenital bicuspid pulmonary valve (BPV) is a condition of valvular stenosis, and the occurrence of congenital BPV is often associated with TOF. Dynamic computational models of normal pulmonary root (PR) with tri-leaflet and PR with BPV in patients with TOF were developed to investigate the effect of geometric structure of BPV on valve stress and strain distributions. The pulmonary root geometry included valvular leaflets, sinuses, interleaflet triangles and annulus. Mechanical properties of pulmonary valve leaflet… More >

  • Open Access

    ABSTRACT

    Biomechanical Implications of Bicuspid Pulmonary Valve Dynamic Deformation in Patients with Repaired Tetralogy of Fallot

    Caili Li1, Jing Yao2, Chun Yang3, Di Xu2, Liang Wang4, Dalin Tang4,5,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 77-78, 2019, DOI:10.32604/mcb.2019.05745

    Abstract Pulmonary valve stenosis (PVS) is one common post-operative problem in patients with tetralogy of Fallot (TOF) after repair. Congenital bicuspid pulmonary valve (BPV) is a condition of valvular stenosis, and the occurrence of congenital BPV is often associated with TOF. Compared with the biomechanical simulation model of the bicuspid aortic valve, the BPV is often neglected. In this study, we developed a dynamic biomechanical model of a simulated normal pulmonary root (PR) with tri-leaflet and a model of simulated PR with BPV in patients with repaired TOF in order to describe the effect of geometric… More >

  • Open Access

    ARTICLE

    Computational Modeling of Human Bicuspid Pulmonary Valve Dynamic Deformation in Patients with Tetralogy of Fallot

    Caili Li1, §, Christopher Baird2, Jing Yao3, Chun Yang4, Liang Wang5, Han Yu5, Tal Geva6, Dalin Tang5*, 7, §

    CMES-Computer Modeling in Engineering & Sciences, Vol.119, No.1, pp. 227-244, 2019, DOI:10.32604/cmes.2019.06036

    Abstract Pulmonary valve stenosis (PVS) is one common right ventricular outflow tract obstruction problem in patients with tetralogy of Fallot (TOF). Congenital bicuspid pulmonary valve (BPV) is a condition of valvular stenosis, and the occurrence of congenital BPV is often associated with TOF. Dynamic computational models of normal pulmonary root (PR) with tri-leaflet and PR with BPV in patients with TOF were developed to investigate the effect of geometric structure of BPV on valve stress and strain distributions. The pulmonary root geometry included valvular leaflets, sinuses, interleaflet triangles and annulus. Mechanical properties of pulmonary valve leaflet… More >

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