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  • Open Access

    ARTICLE

    Time-Course of Changes in Astrocyte Endfeet Damage in the Hippocampus Following Experimental Ischemia and Reperfusion Injury

    Myoung Cheol Shin1, Tae-Kyeong Lee2, Dae Won Kim3, Joon Ha Park4, Moo-Ho Won1, Choong-Hyun Lee5,*, Ji Hyeon Ahn6,*

    BIOCELL, Vol.49, No.6, pp. 1071-1083, 2025, DOI:10.32604/biocell.2025.065506 - 24 June 2025

    Abstract Background: Astrocyte endfeet (AEF) serves as a key element of the blood-brain barrier and is important for the survival and maintenance of neuronal function. However, the immunohistochemical and ultrastructural changes of AEF in the CA1 and CA3 areas of the hippocampus over time following cerebral ischemia-reperfusion (IR) injury have not been well elucidated. Objectives: We investigated chronological changes in AEF in the gerbil hippocampal CA1 area from 3 h to 10 days following transient forebrain ischemia (TFI), and examined their association with neuronal death and tissue repair following IR injury. Changes in the CA3 area… More >

  • Open Access

    ARTICLE

    Butyrophilin Downregulation in Chronic Lymphocytic Leukaemia: An Important Barrier to γδ T Cell-Mediated Cytotoxicity

    Natalia Lehman, Agnieszka Bojarska-Junak, Michał Zarobkiewicz*

    BIOCELL, Vol.49, No.6, pp. 1085-1099, 2025, DOI:10.32604/biocell.2025.063960 - 24 June 2025

    Abstract Introduction: Butyrophilins (BTNs) belong to the immunoglobulin superfamily; they play crucial roles in immune regulation, especially in γδ T cell activation. While their expression has been studied in solid tumours, their involvement in hematologic malignancies remains poorly understood. Objectives: We hypothesised that BTNs are dysregulated in chronic lymphocytic leukaemia (CLL), contributing to γδ T cell dysfunction and potentially influencing disease progression. Methods: In this study, we analyzed publicly available microarray and RNA-seq datasets to investigate the expression patterns of BTN genes in CLL. Results: Our findings reveal significant dysregulation of BTN gene expression in CLL, with BTN2A1, BTN3A1, BTN3A2,… More >

  • Open Access

    ARTICLE

    Grafting Modification of Cellulose Nanofibril with 2-(N,N-Dimethylamino) Ethyl Methacrylate and 2-Hydroxyethyl Methacrylate as a Barrier-Improved Coating for Paper-Based Food Packaging

    Noverra Mardhatillah Nizardo1,*, Alifah Nurul Saffanah1, Annisa Fitri Salsabila1, Amanda Aurellia Putri1, Aniek Sri Handayani2, Azizah Intan Pangesty3, Mochamad Chalid3

    Journal of Renewable Materials, Vol.13, No.6, pp. 1209-1227, 2025, DOI:10.32604/jrm.2025.02024-0068 - 23 June 2025

    Abstract Food packaging is becoming popular as the consumption of ready-to-eat food products rises. Easy-to-use, non-biodegradable plastic packaging is commonly used in food packaging, contributing to the deteriorating environmental situation. This issue increases the concern for the environment and encourages the usage of alternative materials. Cellulose nanofibrils (CNF) are abundant and biodegradable, which makes them ideal candidates to replace plastic coatings. The ability to form H-bonds between the hydroxyl groups makes coated paper with CNF have good strength, but poor barrier properties. The barrier properties can be improved by grafting DMAEMA or HEMA onto CNF (CNF-g-PDMAEMA… More > Graphic Abstract

    Grafting Modification of Cellulose Nanofibril with 2-(N,N-Dimethylamino) Ethyl Methacrylate and 2-Hydroxyethyl Methacrylate as a Barrier-Improved Coating for Paper-Based Food Packaging

  • Open Access

    ARTICLE

    Optimizing Solar Air Heater Performance Using Perforated V-Shaped Barriers with Varied Geometric Designs

    Sajjad Tariq A. Shafi, Mohammed K. Al-Saadi, Ameer Abed Jaddoa*

    Frontiers in Heat and Mass Transfer, Vol.23, No.2, pp. 703-719, 2025, DOI:10.32604/fhmt.2025.063118 - 25 April 2025

    Abstract To improve the heat transfer rate and thermal performance of the solar air heater due to low efficiency, new techniques, such as artificial roughness, barriers, and obstacles, should be used to increase the heat exchange between the fluid and the absorber. In this research, perforated V-shaped blockages with new geometric shapes, which are circular, hexagonal, square, rectangular, and triangular, were used. They were fixed on the absorber plate inside the channel with dimensions of 1.5 m × 0.5 m × 0.05 m, which increased the exit temperature of the air passing through the channel. The… More > Graphic Abstract

    Optimizing Solar Air Heater Performance Using Perforated V-Shaped Barriers with Varied Geometric Designs

  • Open Access

    ARTICLE

    Barber Optimization Algorithm: A New Human-Based Approach for Solving Optimization Problems

    Tareq Hamadneh1, Belal Batiha2, Omar Alsayyed3, Widi Aribowo4, Zeinab Montazeri5, Mohammad Dehghani5,*, Frank Werner6,*, Haider Ali7, Riyadh Kareem Jawad8, Ibraheem Kasim Ibraheem9, Kei Eguchi10

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2677-2718, 2025, DOI:10.32604/cmc.2025.064087 - 16 April 2025

    Abstract In this study, a completely different approach to optimization is introduced through the development of a novel metaheuristic algorithm called the Barber Optimization Algorithm (BaOA). Inspired by the human interactions between barbers and customers, BaOA captures two key processes: the customer’s selection of a hairstyle and the detailed refinement during the haircut. These processes are translated into a mathematical framework that forms the foundation of BaOA, consisting of two critical phases: exploration, representing the creative selection process, and exploitation, which focuses on refining details for optimization. The performance of BaOA is evaluated using 52 standard… More >

  • Open Access

    ARTICLE

    Orchestrating the Phytochemical Content and Bioactivities in the Leaf, Bark, and Fruit Extracts of Cornus capitata Wall

    Deen Bandhu Dimri1, Manisha Nigam1,*, Naresh Singh1, Shilpa Semwal1, Marcello Iriti2,3,*, Abhay Prakash Mishra4

    Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 1007-1027, 2025, DOI:10.32604/phyton.2025.061270 - 31 March 2025

    Abstract Cornus capitata, commonly known as the Himalayan strawberry, is a dogwood species from the family Cornaceae. Dogwood plants have been used extensively to practice conventional medicine due to their biological activities; however, the mechanisms behind these activities, particularly in C. capitata, remain largely unexplored. This study focuses on the preliminary phytochemical screening, antioxidant activity, anti-diabetic potential, and antimicrobial profiling of different extracts (i.e., leaves, bark, and fruit) from C. capitata to evaluate its potential pharmaceutical and medicinal applications. The in-vitro antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, Ferric-reducing antioxidant power (FRAP) assay, and Superoxide Anion Scavenging assay.… More > Graphic Abstract

    Orchestrating the Phytochemical Content and Bioactivities in the Leaf, Bark, and Fruit Extracts of <i>Cornus capitata</i> Wall

  • Open Access

    ARTICLE

    A Barrier-Based Machine Learning Approach for Intrusion Detection in Wireless Sensor Networks

    Haydar Abdulameer Marhoon1,2,*, Rafid Sagban3,4, Atheer Y. Oudah1,5, Saadaldeen Rashid Ahmed6,7

    CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4181-4218, 2025, DOI:10.32604/cmc.2025.058822 - 06 March 2025

    Abstract In order to address the critical security challenges inherent to Wireless Sensor Networks (WSNs), this paper presents a groundbreaking barrier-based machine learning technique. Vital applications like military operations, healthcare monitoring, and environmental surveillance increasingly deploy WSNs, recognizing the critical importance of effective intrusion detection in protecting sensitive data and maintaining operational integrity. The proposed method innovatively partitions the network into logical segments or virtual barriers, allowing for targeted monitoring and data collection that aligns with specific traffic patterns. This approach not only improves the diversit. There are more types of data in the training set,… More >

  • Open Access

    ARTICLE

    Significant Changes in Morphological Traits of 422 Barley (Hordeum vulgare L.) Varieties with Different Registration

    Valentina Spanic1,*, Zvonimir Lalic2, Ivica Berakovic1, Luka Drenjancevic2, Goran Jukic2, Ivan Varnica2

    Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 317-330, 2025, DOI:10.32604/phyton.2025.058201 - 06 March 2025

    Abstract Enhanced grain yield is achieved in barley by developing varieties incorporating grain yield-related and morphological traits derived from different varieties. The evaluation of 28 morphological characteristics of 422 barley varieties was carried out to assess their changes over time from 1973 to 2023. Most barley yield improvement seems to have been achieved by changes in morphological traits where modern varieties out-yielded older varieties for more than 30% (from 1973 to 2023). According to the Pareto chart, the length of the first segment of the rachis was found to be the most important parameter that changed… More >

  • Open Access

    ARTICLE

    Evaluation of Some Egyptian Barley Cultivars Resistance to Foliar Fungal Diseases in Drought-Prone Environments under Field Conditions

    Sally Negm1, Badwy Mohdly2, Motrih Al-Mutiry3, Wael Shehata4, Karima Ahmed5, Mohamed Abou-Zeid2,*, Rana Elessawy6, Ashgan Abdel-Azim5, Amr Abdel-Fattah2, Amani Omar Abuzaid7, Enas A. Almanzalawi7, Tahani M. Alqahtani7, Shouaa A. Alrobaish8, Diaa Abd El Moneim9, Ahmed M. Abbas10,11, Mohammed O. Alshaharni10, Huda Alghamdi10, Shaimaa G. Salama12, Kairy Amer5

    Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 347-377, 2025, DOI:10.32604/phyton.2025.057448 - 06 March 2025

    Abstract Barley (Hordeum vulgare L.) is a significant global crop that thrives in various climatic and drought-stress conditions. Furthermore, increased drought intervals and more significant weather variability resulting from climate change can affect the severity of plant diseases. Therefore, two primary objectives of integrated disease management regarding climate change are identifying cultivars resistant to foliar diseases and understanding disease progression under abiotic stress. In the current study, we assessed the quantitative foliar disease resistance of 17 commercial barley cultivars under both normal and water stress conditions over two growing seasons (from 2020/21 to 2021/22). The findings demonstrated… More >

  • Open Access

    REVIEW

    Quick Response Code Security Attacks and Countermeasures: A Systematic Literature Review

    David Njuguna*, John Ndia

    Journal of Cyber Security, Vol.7, pp. 1-20, 2025, DOI:10.32604/jcs.2025.059398 - 18 February 2025

    Abstract A quick response code is a barcode that allows users to instantly access information via a digital device. Quick response codes store data as pixels in a square-shaped grid. QR codes are prone to cyber-attacks. This assault exploits human vulnerabilities, as users can scarcely discern what is concealed in the quick response code prior to usage. The aim of the study was to investigate Quick Response code attack types and the detection techniques. To achieve the objective, 50 relevant studies published between the year 2010 and 2024 were identified. The articles were obtained from the… More >

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