Norman Aiad^1,2,3,7, Mark V. Sherrid^1,7, Adam J. Small¹, Youssef Elnabawi^1,7, Jodi Feinberg¹, Leon Axel^1,4, Ralph Mosca⁵, T. K. Susheel Kumar⁵, Michael Argilla⁶, Dan G. Halpern^1,7,*

Congenital Heart Disease, Vol.18, No.3, pp. 267-277, 2023, DOI:10.32604/chd.2023.025853 - 09 June 2023

Abstract Introduction: We sought to investigate whether the development of sub-pulmonic systolic anterior motion (SAM) may be inherent to the anatomy of the the mitral valve (MV) or affected by external factors, such as a dilated right ventricle or chest abnormalities in d-looped transposition of the great arteries post atrial switch operation (d-TGA/AtS). Methods: Analysis was performed of clinical and cardiac imaging studies acquired on 19 adult patients with d-TGA/AtS (age 42 ± 6 years old, 56% male) between 2015–2019. Echocardiography data included mitral apparatus anatomy, and CT/MRI data included biventricular dimensions, function, and Haller index… More >

Masataka Ogiso^1,2, Kei Inai^1,*, Morio Shoda², Nobuhisa Hagiwara², Hisashi Sugiyama¹

Congenital Heart Disease, Vol.15, No.6, pp. 483-493, 2020, DOI:10.32604/CHD.2020.013058 - 02 November 2020

Abstract Background: Pulmonary hypertension (PH) is one of the complications that can occur after the atrial switch procedure for transposition of the great arteries (TGA). This study aimed to assess the characteristics and prognosis of late-onset PH after the atrial switch procedure using catheterization data. Methods and Results: We retrospectively identified 40 patients with TGA after the atrial switch procedure that underwent catheterization between April 2007 and March 2020. Eligible patients were divided into two groups based on PH presence (PH group, n = 13 [33%]; non-PH group, n = 27 [67%]). Adverse events were defined as cardiac… More >

Yoann Perreux¹, Marie Alexandre Chaix², Anna Kamp³, François-Pierre Mongeon², Magali Pham², Loïc Boussel¹, Roland Henaine¹, Annie Dore², Blandine Mondésert², Sylvie Di-Filippo¹, Paul Khairy², Francis Bessiere^1,*

Congenital Heart Disease, Vol.15, No.6, pp. 473-482, 2020, DOI:10.32604/CHD.2020.013032 - 02 November 2020

Abstract Sudden cardiac death and heart failure are well known long-term complications after atrial switch for D-transposition of the great arteries (D-TGA). Right systemic ventricular dysfunction is common and myocardial ischemia has been implicated as a putative mechanism for sudden death, with coronary anomalies prevalent in 30% of cases. We sought to assess an association between adverse events and coronary anomalies in patients with D-TGA and atrial switch surgery. An observational study was conducted in 3 tertiary centers (Montreal Heart Institute, Canada, Nationwide Children’s hospital, Chicago, USA and Hopital cardiologique Louis Pradel de Lyon, France). Adults… More >

Margaret M. Samyn^1,2, Ke Yan¹, Conor Masterson³, Benjamin H. Goot^1,2, David Saudek^1,2, Julie Lavoie², Aaron Kinney², Mary Krolikowski¹, Kan Hor^4,5, Scott Cohen^1,2

Congenital Heart Disease, Vol.14, No.6, pp. 1138-1148, 2019, DOI:10.1111/chd.12861

Abstract Objective: Patients with Dextro-transposition of the great arteries status post atrial switch (dTGA s/p atrial switch) are “at-risk” for systemic right ventricular (RV) dysfunction. Due to complex RV geometry, echocardiography (Echo) does not allow accurate determination of ejection fraction (EF), but cardiac magnetic resonance imaging (CMR) allows quantitative right ventricular assessment. Measures of ventricular deformation may be precursors to global ventricular dysfunction. The primary aim of this study was to characterize imaging and clinical findings for adult patients with dTGA s/p atrial switch.
Design: This was a retrospective cohort study of patients with dTGA s/p atrial switch… More >

Magalie Ladouceur^1,2,3, Nadjia Kachenoura⁴, Gilles Soulat^1,3, Emilie Bollache⁴, Alban Redheuil⁴, Michel Azizi³, Christophe Delclaux³, Gilles Chatellier³, Pierre Boutouyrie^1,3, Laurence Iserin³, Damien Bonnet^2,3, Elie Mousseaux^1,3

Congenital Heart Disease, Vol.12, No.4, pp. 458-466, 2017, DOI:10.1111/chd.12472

Abstract Objectives: We aimed (1) determine if systemic right ventricle filling parameters influence systemic right ventricle stroke volume in adult patients with D-transposition of the great arteries (D-TGA) palliated by atrial switch, using cardiac magnetic resonance imaging and echocardiography, and (2) to study relationship of these diastolic parameters with exercise performance and BNP, in patients with preserved systolic systemic right ventricle function.
Design: Single-center, cross-sectional, prospective study.
Setting: In patients with D-TGA palliated by atrial switch, diastolic dysfunction of the systemic right ventricle may precede systolic dysfunction.
Methods: Forty-five patients with D-TGA and atrial switch and 45 age and sex-matched… More >