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    ARTICLE

    Novel oral anticoagulant use in adult Fontan patients: A single center experience

    Justin Georgekutty1, Amir Kazerouninia2, YunFei Wang3, Peter R. Ermis4, Dhaval R. Parekh4, Wayne J. Franklin4, Wilson W. Lam4

    Congenital Heart Disease, Vol.13, No.4, pp. 541-547, 2018, DOI:10.1111/chd.12603

    Abstract Objective: Adult Fontan patients are at increased risk for thrombosis and thromboembolic complications leading to increased morbidity and mortality. Most are prescribed antiplatelet or anticoagulant therapy for thromboprophylaxis; novel oral anticoagulants (NOACs) are uncommonly used given lack of data on their use in this population and generalized concerns regarding Fontan patients’ abnormal coagulation. We report the largest single-center experience with the use of NOACs for treatment and prophylaxis of thrombosis and thromboembolism in adult Fontan patients.
    Results: A retrospective chart review identified 21 patients (11 female, 10 male), median age 33 years (18-50) at first initiation, who… More >

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