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    ARTICLE

    Disease progression and variation in clinical practice for isolated bicuspid aortic valve in children

    Melissa S.W. Yamauchi1,2, Michael D. Puchalski1,2, Hsin Ti Weng1, Nelangi M. Pinto1,2, Susan P. Etheridge1,2, Angela P. Presson1, Lloyd Y. Tani1,2, L. LuAnn Minich1,2, Richard V. Williams1,2

    Congenital Heart Disease, Vol.13, No.3, pp. 432-439, 2018, DOI:10.1111/chd.12591

    Abstract Background: Disease progression of an isolated bicuspid aortic valve (BAV) in children is poorly understood and adult management guidelines may not be applicable. Thus, we sought to evaluate disease progression of pediatric isolated BAV and its relationship to current management practices.
    Methods: Children with a BAV and ≤mild aortic stenosis (AS) and/or aortic regurgitation (AR) at the time of initial evaluation were included in this retrospective cohort study (1/2005-12/ 2014). Outcomes included change in z-scores for aortic root and ascending aorta diameters, cardiac interventions, adverse outcomes, recommended follow-up interval, and frequency of cardiac imaging studies at each… More >

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