Marie Laure Yammine^#,*, Camilla Calvieri^#, Marcello Chinali, Salvatore Giannico, Giulia Cafiero, Ugo Giordano

Congenital Heart Disease, Vol.16, No.5, pp. 457-467, 2021, DOI:10.32604/CHD.2021.015896 - 03 June 2021

Abstract Background: In recent decades, aortic stenting has become a promising alternative to surgery for both native aortic coarctation and re-stenosis in children and adults. However, comparative long-term outcomes have poorly been investigated. Methods: We included 212 patients with previous aortic repair (19 ± 8.7 years) divided into 3 groups: 139 with single-time surgical repair (CoA-S group); 18 with single-time percutaneous stenting (CoA-PS group); and 55 hybrid patients with multiple aortic procedures because of re-coarctation occurrence (CoA-H group). All patients underwent 24-hour ambulatory blood pressure monitoring and trans-thoracic echocardiography. Results: After a median follow-up of 17 years after… More >

Nicola Maschietto¹, Luca Semplicini², Giulio Ceolotto², Arianna Cattelan², Helen Poser³, Ilaria Iacopetti³, Gabriele Gerardi³, Giulia Maria De Benedictis³, Tommaso Pilla³, Daniele Bernardini³, Luca Aresu⁴, Stefania Rizzo⁵, Cristina Basso⁵, Andrea Semplicini², Ornella Milanesi¹

Congenital Heart Disease, Vol.12, No.1, pp. 74-83, 2017

Abstract Background: Stent implantation is the treatment of choice for adolescents and adults with aortic coarctation (CoAo). Despite excellent short-term results, 20%–40% of the patients develop arterial hypertension later in life, which was attributed to inappropriate response of the aortic baroreceptors to increased stiffness of the ascending aorta (ASAO), either congenital or induced by CoAo repair. In particular, it has been hypothesized that stent itself may cause or sustain hypertension. Therefore, we aimed to study the hemodynamic and structural impact following stent implantation in the normal aorta of a growing animal.
Methods: Eight female sheep completed the study… More >