Brian A. Boe1, Mark D. Norris2, Jeffrey D. Zampi2, Albert P. Rocchini2, Gregory J. Ensing2
Congenital Heart Disease, Vol.12, No.6, pp. 733-739, 2017, DOI:10.1111/chd.12514
Abstract Objective: We sought to identify a time during cardiac ejection when the instantaneous pressure
gradient (IPG) correlated best, and near unity, with peak-to-peak systolic ejection gradient (PPSG)
in patients with congenital aortic stenosis. Noninvasive echocardiographic measurement of IPG
has limited correlation with cardiac catheterization measured PPSG across the spectrum of disease
severity of congenital aortic stenosis. A major contributor is the observation that these measures
are inherently different with a variable relationship dependent on the degree of stenosis.
Design: Hemodynamic data from cardiac catheterizations utilizing simultaneous pressure measurements from the left ventricle (LV) and ascending aorta (AAo)… More >