Ersin Çagrı Şimşek1, Selcen Yakar Tülüce2, Kamil Tülüce3, Sadık Volkan Emren2, Serap Çuhadar4, Cem Nazlı2
Congenital Heart Disease, Vol.14, No.2, pp. 256-263, 2019, DOI:10.1111/chd.12718
Abstract Objective: The bicuspid aortic valve (BAV) is the most common congenital heart dis‐
ease. The process of aortic dilatation is not completely clear in patients with the BAV.
Apelin is a peptide found at high levels in vascular endothelial cells which has a role
in vascular regulation and cardiovascular function. The aim of this study was to de‐
termine the relationship between serum apelin levels and ascending aortic dilatation
in adult patients with BAV.
Design: This cross‐sectional study included 62 patients with isolated BAV and to an
age, gender, and body mass index‐matched control group of 58… More >
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