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  • Open Access

    REVIEW

    Review on analytical technologies and applications in metabolomics

    XIN MENG*, YAN LIU, SHUJUN XU, LIANRONG YANG, RUI YIN

    BIOCELL, Vol.48, No.1, pp. 65-78, 2024, DOI:10.32604/biocell.2023.045986 - 30 January 2024

    Abstract Over the past decade, the swift advancement of metabolomics can be credited to significant progress in technologies such as mass spectrometry, nuclear magnetic resonance, and multivariate statistics. Currently, metabolomics garners widespread application across diverse fields including drug research and development, early disease detection, toxicology, food and nutrition science, biology, prescription, and chinmedomics, among others. Metabolomics serves as an effective characterization technique, offering insights into physiological process alterations in vivo. These changes may result from various exogenous factors like environmental conditions, stress, medications, as well as endogenous elements including genetic and protein-based influences. The potential scientific outcomes More > Graphic Abstract

    Review on analytical technologies and applications in metabolomics

  • Open Access

    ARTICLE

    Knowledge-Based Efficient N-1 Analysis Calculation Method for Urban Distribution Networks with CIM File Data

    Lingyu Liang1, Xiangyu Zhao1,*, Wenqi Huang1, Liming Sun2,3, Ziyao Wang3, Yaosen Zhan2

    Energy Engineering, Vol.120, No.12, pp. 2839-2856, 2023, DOI:10.32604/ee.2023.042042 - 29 November 2023

    Abstract The N-1 criterion is a critical factor for ensuring the reliable and resilient operation of electric power distribution networks. However, the increasing complexity of distribution networks and the associated growth in data size have created a significant challenge for distribution network planners. To address this issue, we propose a fast N-1 verification procedure for urban distribution networks that combines CIM file data analysis with MILP-based mathematical modeling. Our proposed method leverages the principles of CIM file analysis for distribution network N-1 analysis. We develop a mathematical model of distribution networks based on CIM data and… More >

  • Open Access

    ARTICLE

    EFFECTS OF VISCOUS DISSIPATION AND AXIAL HEAT CONDUCTION ON FORCED CONVECTION DUCT FLOW OF HERSCHEL-BULKLEY FLUID WITH UNIFORM WALL TEMPERATURE OR CONVECTIVE BOUNDARY CONDITIONS

    Rabha Khatyr*, Jaafar Khalid Naciri

    Frontiers in Heat and Mass Transfer, Vol.19, pp. 1-8, 2022, DOI:10.5098/hmt.19.23

    Abstract The aim is to study the asymptotic behavior of the temperature field for the laminar forced convection of a Herschel-Bulkley fluid flowing in a circular duct considering both viscous dissipation and axial heat conduction. The asymptotic bulk and mixing Nusselt numbers and the asymptotic bulk and mixing temperature distribution are evaluated analytically in the cases of uniform wall temperature and convection with an external isothermal fluid. In particular, it has been proved that the fully developed value of Nusselt number for convective boundary conditions is independent of the Biot number and is equal to the More >

  • Open Access

    ARTICLE

    On the Dynamics of a Viscoelastic Fluid-Conveying Nanotube

    Ola Adil Ibrahim1, Gunawan Widjaja2, Abdulhussien N. Alattabi3, Krishanveer Singh4, Yasser Fakri Mustafa5, P. A. Krovopuskov6, Mustafa M. Kadhim7,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.4, pp. 1137-1151, 2022, DOI:10.32604/fdmp.2022.019921 - 06 April 2022

    Abstract The objective of the presented study is to perform a vibration analysis and investigate the stability of a viscoelastic-fluid conveying pipe with an intermediate support. The mathematical model is elaborated in the framework of the Euler-Bernoulli beam theory in combination with the Kelvin-Voight viscoelastic approach. The resulting differential equation of motion and the related boundary conditions and compatibility conditions in the mid-span support are solved analytically using a power series method. The results show that an intermediate support located at ξs = 0.1 and ξs = 0.5 increases the critical velocity up to 35% and 50.15%, More >

  • Open Access

    ARTICLE

    EFFECTS OF VISCOUS DISSIPATION AND AXIAL HEAT CONDUCTION ON FORCED CONVECTION FLOW OF HERSCHELBULKLEY FLUID IN CIRCULAR DUCT WITH AXIALLY VARIABLE WALL HEAT FLUX

    Rabha Khatyr*, Jaafar Khalid Naciri

    Frontiers in Heat and Mass Transfer, Vol.15, pp. 1-11, 2020, DOI:10.5098/hmt.15.5

    Abstract The present study focuses on the effects of viscous dissipation and axial heat conduction on the asymptotic behavior of the laminar forced convection in a circular duct for a Herschel-Bulkley fluid with variable wall heat flux. Analytical asymptotic solutions are presented for the case of axial variations of the wall heat flux, with finite non-vanishing values at infinity along the flow direction. The asymptotic bulk and mixing Nusselt numbers and the asymptotic bulk and mixing temperature distributions are evaluated analytically in the case of axially variable wall heat flux for which polynomial and logarithmic functions More >

  • Open Access

    ARTICLE

    A Fast Product of Conditional Reduction Method for System Failure Probability Sensitivity Evaluation

    Jie Yang1,2, Changping Chen1,2,*, Ao Ma1

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.3, pp. 1159-1171, 2020, DOI:10.32604/cmes.2020.09640 - 15 December 2020

    Abstract System reliability sensitivity analysis becomes difficult due to involving the issues of the correlation between failure modes whether using analytic method or numerical simulation methods. A fast conditional reduction method based on conditional probability theory is proposed to solve the sensitivity analysis based on the approximate analytic method. The relevant concepts are introduced to characterize the correlation between failure modes by the reliability index and correlation coefficient, and conditional normal fractile the for the multi-dimensional conditional failure analysis is proposed based on the two-dimensional normal distribution function. Thus the calculation of system failure probability can… More >

  • Open Access

    ARTICLE

    Dynamic Analyses of a Simply Supported Double-Beam System Subject to a Moving Mass with Fourier Transform Technique

    Lizhong Jiang1,2, Xilin Chai1,2, Zhihua Tan1,2, Wangbao Zhou1,2,*, Yulin Feng1,2, Zhipeng Lai1,2, Lan Zheng1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.1, pp. 291-314, 2019, DOI:10.32604/cmes.2019.07805

    Abstract In order to study the dynamic characteristics of a simply supported double-beam system under a moving mass, the system of fourth-order dynamic partial differential equations of a simply supported double-beam system was transformed into a system of second-order dynamic ordinary differential equations relative to time coordinates by performing the finite sin-Fourier Transform relative to space coordinates. And the analytical solution of the dynamic response of the simply supported double-beam system under a moving mass was obtained by solving the system of dynamic ordinary differential equations. The analytical method and ANSYS numerical method were used to… More >

  • Open Access

    ARTICLE

    3-D Temperature Fields in Laminated Shells Subjected to Thermo-Loads

    Hai Qian1,*, Ding Zhou2, Bin Gu1, Rathnayaka Mudiyanselage D. M. S.3

    Structural Durability & Health Monitoring, Vol.12, No.4, pp. 281-298, 2018, DOI:10.32604/sdhm.2018.04618

    Abstract The temperature fields in the laminated shells were studied, including open cylindrical shells and cylindrical shells, according to the thermal theory. Analytical solution of the temperature in the shells with the known temperature on the surfaces was present. The thinning layer approach was introduced to simplify the three-dimensional heat conduction equation. Firstly, the layered shell was divided into N thinner layers. The governing equation was simplified by replacing the variable r by r0 in the center line of every thin layer. The general solutions of temperature satisfying the simplified three-dimensional governing equation in single-layered shell… More >

  • Open Access

    ARTICLE

    Least Squares Stochastic Finite Element Method in Structural Stability Analysis of Steel Skeletal Structures1

    Marcin Kamiński2, Jacek Szafran3

    CMES-Computer Modeling in Engineering & Sciences, Vol.107, No.1, pp. 27-57, 2015, DOI:10.3970/cmes.2015.107.027

    Abstract Basic probabilistic characteristics and reliability indices of critical forces for high steel skeletal towers are numerically modeled by using the Stochastic, perturbation-based Finite Element Method. It is implemented together with the Weighted Least Squares Method and compared with the Monte-Carlo simulation as well as with the semi-analytical Probabilistic FEM. The Finite Element Method solution to the stability problem for a full 3D model of a tower accounts for both first and second order effects known from the engineering codes as the so-called P-delta effect. Two different Gaussian input random variables are adopted here – Young More >

  • Open Access

    ARTICLE

    Analytical Method for Simulation of Buckling and Post-buckling Behaviour of Curved Pates

    Joo Shin Park1, Jung Kwan Seo2,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.106, No.4, pp. 291-308, 2015, DOI:10.3970/cmes.2015.106.291

    Abstract Ships, ship-shaped offshore structures, land-based structures and aerospace structures typically consist of various curved plate components. It is difficult to simulate the buckling and post-buckling of curved thin and/or thick plates that have characteristics of nonlinear structural mechanics, such as nonlinear behaviour when loading is applied. The elastic post-buckling behaviour of a curved plate is very complex, and accompanied by mode changes due to the occurrence of secondary buckling behaviour. Therefore, it is very important to clarify the elastic post-buckling behaviour when subjected to axial loading. The aim of this study was to derive an More >

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