Oleh Koshovyi1,2,*, Janne Sepp1, Valdas Jakštas3, Vaidotas Žvikas3, Karina Tolmacheva4, Igor Kireyev4, Jyrki Heinämäki1, Ain Raal1,*
Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2909-2925, 2024, DOI:10.32604/phyton.2024.056536
- 30 November 2024
Abstract Pineappleweed (Matricaria discoidea DC., Asteraceae) herb is an essential oil containing raw material with spasmolytic and anti-inflammatory activity. It is also rich in phenolics, which may be used in pharmaceutical practice. This study aimed to investigate the phenolic and amino acid composition and the hyporific and analgesic effects of the M. discoidea aqueous-ethanolic extract and its amino acid modifications. In addition, we developed a polyethylene oxide gel formulation with M. discoidea extracts for the 3D-printed oral solid dosage preparations. In M. discoidea extracts, 16 phenolic substances and 14 amino acids were established. The extract and its amino acid preparations More >
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