Ruiping Wang, Chuang He, Shuo Zhang, Miaojun Xu^*, Zhuo Wang, Xiaoli Li^*, Bin Tao, Suliang Gao, Bin Li^*

Journal of Polymer Materials, Vol.42, No.4, pp. 1035-1049, 2025, DOI:10.32604/jpm.2025.073108 - 26 December 2025

Abstract The fabrication of highly flame-retardant polyamide 6 (PA6) composites is of great significance for expanding their practical applications. Herein, a new flame-retardant system (ADP/FA) was developed by combining aluminum diethylphosphinate (ADP) with excellent flame retardancy and fly ash (FA), an economical and environmentally friendly industrial waste. Due to the synergistic flame-retardant effect of ADP/FA in the condensed phase and gas phase, the PA6 composite containing only 11 wt% of ADP/FA (mass ratio 93:7) obtained vertical burning (UL-94) tests V-0 rating with a limiting oxygen index (LOI) of 30.9%. To obtain the same flame-retardant level of… More > Graphic Abstract

Wenjun Hu, Liquan Zhang^*

Journal of Polymer Materials, Vol.42, No.4, pp. 1159-1179, 2025, DOI:10.32604/jpm.2025.072450 - 26 December 2025

Abstract Addressing the persistent challenge of shale hydration and swelling in water-based drilling fluids (WBDFs), this study developed a smart thermo-responsive shale inhibitor, Hyperbranched Polyethyleneimine-Propylene Oxide-N-isopropylacrylamide (HPN). It was synthesized by grafting hyperbranched polyethyleneimine (HPEI) with propylene oxide (PO) and N-isopropylacrylamide (NIPAM), creating a synergistic hydration barrier through hydrophobic association and temperature-triggered pore plugging. Structural characterization by Fourier-Transform Infrared (FTIR) spectroscopy and gel permeation chromatography (GPC) confirmed the successful formation of the HPN terpolymer, revealing a unique “cationic–nonionic” amphiphilic architecture with temperature-responsive properties. Performance evaluation demonstrated that HPN significantly outperforms conventional inhibitors, including potassium chloride (KCl),… More >

Qiang Sun^1,2,*, Zheng-Song Qiu¹, Tie Geng², Han-Yi Zhong¹, Weili Liu², Yu-Lin Tang², Jin-Cheng Dong²

Journal of Polymer Materials, Vol.42, No.3, pp. 757-772, 2025, DOI:10.32604/jpm.2025.069808 - 30 September 2025

Abstract Addressing the critical challenges of viscosity loss and barite sag in synthetic-based drilling fluids (SBDFs) under high-temperature, high-pressure (HTHP) conditions, this study innovatively developed a hyperbranched amide polymer (SS-1) through a unique stepwise polycondensation strategy. By integrating dynamic ionic crosslinking for temperature-responsive rheology and rigid aromatic moieties ensuring thermal stability beyond 260°C, SS-1 achieves a molecular-level breakthrough. Performance evaluations demonstrate that adding merely 2.0 wt% SS-1 significantly enhances key properties of 210°C-aged SBDFs: plastic viscosity rises to 45 mPa·s, electrical stability (emulsion voltage) reaches 1426 V, and the sag factor declines to 0.509, outperforming conventional More >

Kumudesh Mishra^1,2,*, Or Kakhlon^1,2

BIOCELL, Vol.49, No.7, pp. 1101-1123, 2025, DOI:10.32604/biocell.2025.061725 - 25 July 2025

Abstract Mitochondria are central organelles in cellular metabolism, orchestrating energy production, biosynthetic pathways, and signaling networks. Nicotinamide adenine dinucleotide (NAD⁺) and its reduced form (NADH) are essential for mitochondrial metabolism, functioning both as redox coenzymes and as signaling agents that help regulate cellular balance. Thus, while its major role is in energy production, NAD⁺ is widely recognized as a metabolic cofactor and also serves as a substrate for various enzymes involved in cellular signaling, like sirtuins (SIRTs), poly (ADP-ribosyl) polymerases (PARPs), mono (ADP-ribosyl) transferases, and CD38. Sirtuins, a family of NAD⁺-dependent deacetylases, are critical in this regulatory network.… More >

Darya Ivashkevich, Arina Ponomarenko^*, Igor Manzhulo, Inessa Dyuizen

BIOCELL, Vol.49, No.4, pp. 607-627, 2025, DOI:10.32604/biocell.2025.061606 - 30 April 2025

Abstract The high prevalence of obesity and associated nonalcoholic fatty liver disease (NAFLD) in the population determines the increased interest in identifying molecular targets for regulating the processes underlying these pathologies. The search for new endogenous bioregulators of lipid metabolism and their inclusion in therapeutic regimens for the treatment of patients is becoming a potentially promising direction in science and medicine. Oleoylethanolamide (OEA) is an endogenous lipid mediator capable of exerting multiple hypolipidemic, anti-inflammatory, and hepatoprotective effects mediated by agonism with receptors of the peroxisome proliferator-activated receptor (PPAR) family (PPAR-α and PPAR-γ). This review focuses on More >

HUI ZHOU^#, ZHENGYU YU^#, JING XU, ZHONGWANG WANG, YALI TAO, JINJIN WANG, PEIPEI YANG, JINRONG YANG^*, TING NIU^*

Oncology Research, Vol.32, No.12, pp. 1903-1919, 2024, DOI:10.32604/or.2024.048138 - 13 November 2024

Abstract Background: Dihydrolipoamide S-acetyltransferase (DLAT) is a subunit of the pyruvate dehydrogenase complex (PDC), a rate-limiting enzyme complex, that can participate in either glycolysis or the tricarboxylic acid cycle (TCA). However, the pathogenesis is not fully understood. We aimed to perform a more systematic and comprehensive analysis of DLAT in the occurrence and progression of tumors, and to investigate its function in patients’ prognosis and immunotherapy. Methods: The differential expression, diagnosis, prognosis, genetic and epigenetic alterations, tumor microenvironment, stemness, immune infiltration cells, function enrichment, single-cell analysis, and drug response across cancers were conducted based on multiple computational… More > Graphic Abstract

Ravikumar Karthikeyan, Subbiah Rajkumar^*, Balasundaram Ravi

Journal of Polymer Materials, Vol.41, No.3, pp. 131-141, 2024, DOI:10.32604/jpm.2024.055989 - 30 September 2024

Abstract In this study, the Polyamide-12 (PA-12) powdered material in the Selective Laser Sintering (SLS) process has been incorporated as the filler in the composite material to enhance its properties. The PA-12 powder has been made into a form of filament and is primarily used in the Fused Deposition Modelling (FDM) process. The PA-12 has been used with epoxy resin and glass fiber with different proportions. The characterization of materials, including the validation of the presence of PA-12 filler with epoxy, has been evidenced using Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), and Thermogravimetric More >

Annesha Kar¹, Niranjan Karak^1,2,*

Journal of Renewable Materials, Vol.12, No.9, pp. 1507-1540, 2024, DOI:10.32604/jrm.2024.052220 - 25 September 2024

Abstract The pursuit of incorporating eco-friendly reinforcing agents in polymer composites has accentuated the exploration of various natural biomass-derived materials. The burgeoning environmental crisis spurred by the discharge of synthetic dyes into wastewater has catalyzed the search for effective and sustainable treatment technologies. Among the various sorbent materials explored, biochar, being renewable, has gained prominence due to its excellent adsorption properties and environmental sustainability. It has also emerged as a focal point for its potential to replace other conventional reinforcing agents, viz., fumed silica, aluminum oxide, treated clays, etc. This study introduces a novel class of… More > Graphic Abstract

Xiaoyu Chen^*

Journal of Renewable Materials, Vol.12, No.4, pp. 815-826, 2024, DOI:10.32604/jrm.2024.048470 - 12 June 2024

Abstract A novel core-shell hydrogel bead was fabricated for effective removal of methylene blue dye from aqueous solutions. The core, made of sodium alginate-g-polyacrylamide and attapulgite nanofibers, was cross-linked by Calcium ions (Ca). The shell, composed of a chitosan/activated carbon mixture, was then coated onto the core. Fourier transform infrared spectroscopy confirmed the grafting polymerization of acrylamide onto sodium alginate. Scanning electron microscopy images showed the core-shell structure. The core exhibited a high water uptake ratio, facilitating the diffusion of methylene blue into the core. During the diffusion process, the methylene blue was first adsorbed by More > Graphic Abstract

ZHIGANG XIA^1,#, MENGYAO TIAN^1,#, YUCAI CHENG¹, WENFANG YI¹, ZEFAN DU^1,2, TIANWEN LI^1,2, YUCHEN WEN¹, LINDI LI^1,2, YONG LIU^1,2,*, CHUN CHEN^1,*

Oncology Research, Vol.32, No.6, pp. 1109-1118, 2024, DOI:10.32604/or.2024.049792 - 23 May 2024

Abstract Background: Chimeric antigen receptor T (CAR-T) cell therapy has achieved marked therapeutic success in ameliorating hematological malignancies. However, there is an extant void in the clinical guidelines concerning the most effective chemotherapy regimen prior to chimeric antigen receptor T (CAR-T) cell therapy, as well as the optimal timing for CAR-T cell infusion post-chemotherapy. Materials and Methods: We employed cell-derived tumor xenograft (CDX) murine models to delineate the optimal pre-conditioning chemotherapy regimen and timing for CAR-T cell treatment. Furthermore, transcriptome sequencing was implemented to identify the therapeutic targets and elucidate the underlying mechanisms governing the treatment regimen.… More >