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    ARTICLE

    Histomorphological and quantitative immunohistochemical changes in the rat pancreas during aging

    F.L. RICCILLO, M.I. BRACAMONTE, G.M. CÓNSOLE, C.L.A. GÓMEZ DUMM

    BIOCELL, Vol.28, No.2, pp. 127-134, 2004, DOI:10.32604/biocell.2004.28.127

    Abstract Although the endocrine pancreas is the purpose of several deep investigations, morphological data referred to the effect of aging on the gland are not homogeneous. The purpose of the current work was to analyze the changes occurring in the pancreas of aged rats, with especial reference to the islet cell populations. Six young (Y), old (O) and senescent (S) male Sprague-Dawley rats were used. The pancreas tails were processed for light microscopy and studied by means of routine stains as well as by immunohistochemical identification of insulin-, glucagon-, somatostatin-, and pancreatic polypeptide- secreting cells (Dako… More >

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