Danielle Kirelik1,2, Mark Fisher2, Michael DiMaria2, Danielle E. Soranno3, Katja M. Gist2
Congenital Heart Disease, Vol.14, No.5, pp. 760-764, 2019, DOI:10.1111/chd.12776
Abstract Background: There are several limitations when using creatinine to estimate glomerular filtration rate, especially in children with chronic medical conditions who are at
high risk of kidney dysfunction. Cystatin C has been the recent focus of research as a
replacement biomarker for creatinine. Our objective was to compare the 2 biomarkers in pediatric single‐ventricle heart disease patients who have undergone the
Fontan operation. We hypothesized that there would be poor correlation and agreement between the 2 estimates of renal function.
Methods: This was a single center retrospective chart review of 20 patients who had
previously undergone Fontan… More >