Oncology Research Editorial Office

Oncology Research, Vol.32, No.11, pp. 1821-1821, 2024, DOI:10.32604/or.2024.056895 - 16 October 2024

Abstract This article has no abstract. More >

JINXIA CHEN^1,2,3,#, SULI DAI^1,2,#, GENG ZHANG^4,5, SISI WEI^1,2, XUETAO ZHAO³, YANG ZHENG^1,2, YAOJIE WANG^1,2, XIAOHAN WANG^1,2, YUNJIANG LIU^4,5,*, LIANMEI ZHAO^1,2,*

Oncology Research, Vol.32, No.11, pp. 1791-1802, 2024, DOI:10.32604/or.2024.049348 - 16 October 2024

Abstract Background: Triple-negative breast cancer (TNBC) is a heterogeneous, recurring cancer characterized by a high rate of metastasis, poor prognosis, and lack of efficient therapies. KBU2046, a small molecule inhibitor, can inhibit cell motility in malignant tumors, including breast cancer. However, the specific targets and the corresponding mechanism of its function remain unclear. Methods: In this study, we employed (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H tetrazolium) (MTS) assay and transwell assay to investigate the impact of KBU2046 on the proliferation and migration of TNBC cells in vitro. RNA-Seq was used to explore the targets of KBU2046 that inhibit the motility of TNBC.… More > Graphic Abstract

MIN LIU^1,*, XIA LI², JUN LIU¹, YU LIU¹

BIOCELL, Vol.48, No.10, pp. 1475-1487, 2024, DOI:10.32604/biocell.2024.053227 - 02 October 2024

Abstract Background: Alveolar macrophage pyroptosis exacerbates inflammatory lung diseases, and tanshinone IIA is known for its anti-inflammatory properties. Thus, understanding how tanshinone IIA affects alveolar macrophage pyroptosis is essential. Methods: NR8383 cells were exposed to lipopolysaccharide (LPS) and adenosine triphosphate (ATP). We assessed cell viability, pyroptosis, and the expression of triggering receptors expressed on myeloid cells 2 (TREM2), p-β-catenin, β-catenin, and pyroptosis-related factors. We also examined the interaction between tanshinone IIA and TREM2. Results: Co-stimulation with LPS and ATP significantly reduced NR8383 cell viability, increased pyroptosis, and upregulated pyroptosis-associated factors. Treatment with tanshinone IIA mitigated these effects.… More >

Sumrit Mopoung^*, Narissara Namkaew, Sasiwan Srikasaem

Journal of Renewable Materials, Vol.12, No.8, pp. 1433-1454, 2024, DOI:10.32604/jrm.2024.052925 - 06 September 2024

Abstract Activated carbon preparation from sugarcane leaves and rice straw by carbonization (250°C–400°C) and activation at 500°C were studied. The effects of pre-oxidation, hydrolysis of derived charcoals by boiled KMnO₄ aqueous solution were evaluated. The derived charcoals products were pretreated using oxidation-hydrolysis with 1–5 wt.% KMnO₄ at 100°C and then activated at 500°C. The derived charcoal and activated carbon products were characterized by FTIR, XRD, SEM-EDS and BET. Iodine number and methylene blue number of derived products were also used for the analysis of the products. It was found that fabricated charcoal materials made at 350°C–400°C possess… More > Graphic Abstract

Jawad Raza¹, F. Mebarek-Oudina^2,*, Haider Ali¹, I. E. Sarris³

Frontiers in Heat and Mass Transfer, Vol.22, No.4, pp. 1017-1041, 2024, DOI:10.32604/fhmt.2024.052749 - 30 August 2024

Abstract The current study is dedicated to presenting the Casson nanofluid over a stretching surface with activation energy. In order to make the problem more realistic, we employed magnetic field and slip effects on fluid flow. The governing partial differential equations (PDEs) were converted to ordinary differential equations (ODEs) by similarity variables and then solved numerically. The MATLAB built-in command ‘bvp4c’ is utilized to solve the system of ODEs. Central composite factorial design based response surface methodology (RSM) is also employed for optimization. For this, quadratic regression is used for data analysis. The results are concluded More > Graphic Abstract

Oncology Research Editorial Office

Oncology Research, Vol.32, No.9, pp. 1535-1535, 2024, DOI:10.32604/or.2024.056124 - 23 August 2024

Abstract This article has no abstract. More >

Shihao Feng^1,2,3, Qin Ouyang^1,2,*, Jing Huang^1,2, Xilin Zhang³, Zhongjun Ma⁴, Kun Liang^1,2, Qing Huang^1,2,*

Journal of Renewable Materials, Vol.12, No.7, pp. 1207-1218, 2024, DOI:10.32604/jrm.2024.052579 - 21 August 2024

Abstract Lignin-derived porous carbons have emerged as promising electrode materials for supercapacitors. However, the challenge remains in designing and controlling their structure to achieve ideal electrochemical performance due to the complex molecular structure of lignin and its intricate chemical reactions during the activation process. In this study, three porous carbons were synthesized from lignin by spray drying and chemical activation with varying KOH ratios. The specific surface area and structural order of the prepared porous carbon continued to increase with the increase of the KOH ratio. Thermogravimetric-mass spectrometry (TG-MS) was employed to track the molecular fragments More > Graphic Abstract

RUIFANG LI¹, XINRONG NAN^2,*, MING LI^3,*, OMAR RAHHAL³

Oncology Research, Vol.32, No.8, pp. 1323-1334, 2024, DOI:10.32604/or.2024.046965 - 17 July 2024

Abstract Background: Fibroblast activation protein (FAP), a cell surface serine protease, plays roles in tumor invasion and immune regulation. However, there is currently no pan-cancer analysis of FAP. Objective: We aimed to assess the pan-cancer expression profile of FAP, its molecular function, and its potential role in head and neck squamous cell carcinoma (HNSC). Methods: We analyzed gene expression, survival status, immune infiltration, and molecular functional pathways of FAP in The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) tumors. Furthermore, to elucidate the role of FAP in HNSC, we performed proliferation, migration, and invasion assays… More >

Wei Chen^*, Dingdan Liu, Yue Liang

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 915-938, 2024, DOI:10.32604/fdmp.2024.046335 - 07 June 2024

Abstract This study focuses on the effect of ultrafine waste glass powder on cement strength, gas permeability and pore structure. Varying contents were considered, with particle sizes ranging from 2 to 20 μm. Moreover, alkali activation was considered to ameliorate the reactivity and cementitious properties, which were assessed by using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and specific surface area pore size distribution analysis. According to the results, without the addition of alkali activators, the performance of glass powder mortar decreases as the amount of glass powder increases, affecting various aspects such as strength… More >

Zhengfan Lyu^1,3, Yulin Li^2,3, Mengmeng Fan^1,3,*, Yan Huang¹, Chenguang Li²

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 901-913, 2024, DOI:10.32604/fdmp.2023.043512 - 07 June 2024

Abstract Red mud (RM) is a low-activity industrial solid waste, and its utilization as a resource is currently a hot topic. In this study, the micro characteristics of red mud at different calcination temperatures were analyzed using X-ray diffraction and scanning electron microscopy. The performance of calcined red mud was determined through mortar strength tests. Results indicate that high-temperature calcination can change the mineral composition and microstructure of red mud, and increase the surface roughness and specific surface area. At the optimal temperature of 700°C, the addition of calcined red mud still leads to a decrease More > Graphic Abstract