Zhongwei Wang, Yali Wang, Hongtao Ren, Yingying Jin, Ya Guo

Oncology Research, Vol.25, No.4, pp. 571-577, 2017, DOI:10.3727/97818823455816X14760478220149

Abstract Zinc and ring finger 3 (ZNRF3), which belongs to the E3 ubiquitin ligase family, is involved in the progression and development of cancer. However, the expression and function of ZNRF3 in human nasopharyngeal carcinoma (NPC) remain unclear. Thus, the aim of this study was to investigate the role of ZNRF3 in human NPC. Our results showed that ZNRF3 was downregulated in NPC cell lines. Restoration of ZNRF3 significantly inhibited the proliferation of NPC cells and tumor xenograft growth in vivo. In addition, overexpression of ZNRF3 suppressed migration and invasion, as well as attenuated the epithelial–mesenchymal More >

Md. Abdul Quddus¹, Md. Ataur Rahman¹, Razu Ahmed¹, Mohammad Eyakub Ali², Khokan Kumer Sarker³, Md. Alamgir Siddiky⁴, Mohibur Rahman⁴, Lamya Ahmed Alkeridis⁵, Samy Sayed^6,7, Ahmed Gaber^8,9, Akbar Hossain^10,*

Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 901-922, 2024, DOI:10.32604/phyton.2024.049226

Abstract Garden pea productivity and qualities are hampered in zinc (Zn), boron (B), and molybdenum (Mo) deficient soil. Thus, the combination of micronutrients (i.e., Zn, B, and Mo) and rhizobium is necessary to increase the productivity and quality of garden peas, since this management for garden peas is neglected in Bangladesh. Therefore, the present study was made to assess the effectiveness of rhizobium inoculant singly or in combination with the micronutrients (i.e., Zn, B, and Mo) on growth, yield, nutrient uptake, and quality of garden peas. Treatments were: T = Control, T = Rhizobium inoculation at 50… More >

M. F. Elkady^1,2,*, E. M. El-Sayed², Mahmoud Samy³, Omneya A. Koriem¹, H. Shokry Hassan^4,5

Journal of Renewable Materials, Vol.12, No.2, pp. 369-380, 2024, DOI:10.32604/jrm.2023.046585

Abstract In this study, green zinc oxide (ZnO)/polypyrrole (Ppy)/cellulose acetate (CA) film has been synthesized via solvent casting. This film was used as supporting material for glucose oxidase (GOx) to sensitize a glucose biosensor. ZnO nanoparticles have been prepared via the green route using olive leaves extract as a reductant. ZnO/Ppy nanocomposite has been synthesized by a simple in-situ chemical oxidative polymerization of pyrrole (Py) monomer using ferric chloride (FeCl₃) as an oxidizing agent. The produced materials and the composite films were characterized using X-ray diffraction analysis (XRD), scanning electron microscope (SEM), Fourier transform infrared (FTIR) and… More > Graphic Abstract

JIAZHUANG LI^*, WEI ZHANG, SHOUBAO GAO, LI SUN, QINGYANG TAI, YING LIU

BIOCELL, Vol.47, No.10, pp. 2313-2320, 2023, DOI:10.32604/biocell.2023.029860

Abstract Background: Trastuzumab resistance accounts for chemotherapy failure in gastric cancer patients in clinical practice. The significance of long non-coding RNAs (lncRNAs) in the maintenance of drug resistance in gastric cancer has been already underlined. Method: This study aimed to identify the specific role of lncRNA-ATB in gastric cancer progression and trastuzumab resistance. The downstream miRs of lncRNA-ATB and target genes of miRs were predicted by bioinformatics analysis and verified using dual luciferase reporter assay. Loss- and gain-function assays were performed to explore the roles of lncRNA-ATB, miR-200c, and zinc-finger protein 217 (ZNF217) in the cell functions More >

Sibel Day^*, Nilüfer Koçak-Şahin

Phyton-International Journal of Experimental Botany, Vol.92, No.8, pp. 2461-2471, 2023, DOI:10.32604/phyton.2023.029920

Abstract Aromatic and medicinal plant species having small seeds have field emergence problems due to low nutrient supply. Therefore, Pimpinella anisum seeds were hydro and osmoprimed with 100 mM MgCl₂, CaCl₂, and ZnCl₂, for 2, 4, and 8 h each to compare their growth attributes during germination and seedling establishment stages. Nontreated seeds were used as control. Both hydro and osmo primed seeds were dried for 48 h before, they were sown in plastic trays in growth room conditions to see the impact of treatments on seedling emergence and growth. The maximum root length (12.90 cm), fresh weight (256.30… More >

Fatiha Daoudi^1,*, Abdelkrim Naas¹, Omar Meglali^1,2, Radia Boudaira³, Ahmed Gueddim¹, A. M. Saeed⁴

Energy Engineering, Vol.120, No.8, pp. 1803-1815, 2023, DOI:10.32604/ee.2023.028423

Abstract The numerical simulations were performed using the AMPS-1D simulator to study the effects of the CZTS as an absorber layer and the contacts’ barrier height on the performance of four ZnO/CdS/CZTS solar cells. To obtain the best cell performances, the barrier heights of the back and front contacts were adjusted between 0.01, 0.77, 0.5, and 1.55 eV, respectively. For simulations, we used the lifetime mode, and the device performances were evaluated under AM1.5 illumination spectra. We found that the efficiency, fill factor, and open-circuit voltage were almost constant at a front contact barrier height of… More > Graphic Abstract

NING AN^1,#, HEQING PENG^2,#, MIN HOU³, DUOFENG SU², LIU WANG⁴, XIAOGANG SHEN^5,*, MING ZHANG^1,*

Oncology Research, Vol.31, No.3, pp. 307-316, 2023, DOI:10.32604/or.2023.028564

Abstract Zinc-finger proteins play different roles in cancer; however, the function of zinc-finger protein ZNF575 in cancer remains unclear. In the present study, we aimed to determine the function and expression of ZNF575 in colorectal cancer. Proliferation assay, colony formation assay, and tumor model in mice were used to investigate the function of ZNF575 after ectopic expression of ZNF575 in colorectal cancer (CRC) cells. RNA sequencing, ChIP, and luciferase assays were used to investigate the mechanism behind ZNF575 regulation of CRC cell growth. The expression of ZNF575 was determined by IHC staining in 150 pairs of… More > Graphic Abstract

YANG CAO^1,#, YINING LIU^1,#, YANG YU¹, XIAOFEI GUO¹, XIUXIU WANG¹, WENYA MA¹, HANJING LI², ZHONGYU REN², XINLU GAO², SIJIA LI², HAOYU JI², HONGYANG CHEN², HONG YAN², YANAN TIAN², XIN WANG², BENZHI CAI^1,2,*

BIOCELL, Vol.47, No.6, pp. 1407-1416, 2023, DOI:10.32604/biocell.2023.029080

Abstract Background: Cardiomyocytes derived from human embryonic stem cells (hESCs) are regulated by complex and stringent gene networks during differentiation. Long non-coding RNAs (lncRNAs) exert critical epigenetic regulatory functions in multiple differentiation processes. However, the involvement of lncRNAs in the differentiation of hESCs into cardiomyocytes has not yet been fully elucidated. Here, we identified the key roles of ZFAS1 (lncRNA zinc finger antisense 1) in the differentiation of cardiomyocytes from hESCs. Methods: A model of cardiomyocyte differentiation from stem cells was established using the monolayer differentiation method, and the number of beating hESCs-derived cardiomyocytes was calculated. Gene expression… More >

Adalberto Benavides-Mendoza¹, Rebeca Betancourt-Galindo², Nazario Francisco-Francisco^3,*

Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1831-1840, 2023, DOI:10.32604/phyton.2023.028085

Abstract

Micronutrient nanoparticles (NPs) are currently an option for chemical fertilization and biostimulation in crops. However, there is little information on the phytotoxic or biostimulatory effects of NPs at low concentrations of some elements, such as Zn. In this study, the effect of low concentrations of Zn oxide (ZnO) NPs on germination, growth variables, and nutritional attributes of lettuce (Lactuca sativa L.) was evaluated in comparison to Zn sulfate. Romaine lettuce seeds were treated with ZnSO₄^-- × 7H₂O and ZnO NPs at Zn molar concentrations of 1 × 10⁻³, 5 × 10⁻³, 1 × 10⁻⁴, 5 × 10⁻⁴, 1

… More >

Muhammad Jan^1,*, Muhammad Anwar-Ul-Haq², Talha Javed³, Sadam Hussain^4,*, Ilyas Ahmad⁵, Muhammad Ashraf Sumrah⁶, Javed Iqbal⁷, Babar Hussain Babar⁸, Aqsa Hafeez⁹, Muhammad Aslam⁵, Muhammad Tahir Akbar¹⁰, Marjan Aziz⁶, Khadiga Alharbi¹¹, Izhar Ullah¹²

Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1361-1375, 2023, DOI:10.32604/phyton.2023.026620

Abstract Abiotic stresses are among the major limiting factors for plant growth and crop productivity. Among these, salinity is one of the major risk factors for plant growth and development in arid to semi-arid regions. Cultivation of salt tolerant crop genotypes is one of the imperative approaches to meet the food demand for increasing population. The current experiment was carried out to access the performance of different rice genotypes under salinity stress and Zinc (Zn) sources. Four rice genotypes were grown in a pot experiment and were exposed to salinity stress (7 dS m⁻¹), and Zn (15… More >