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  • Open Access

    RETRACTION

    Retraction: long noncoding RNA CAT104 promotes cell viability, migration, and invasion in gastric carcinoma cells through activation of microRNA-381-inhibiting zinc finger e-box-binding homeobox 1 (ZEB1) expression

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.11, pp. 1821-1821, 2024, DOI:10.32604/or.2024.056895 - 16 October 2024

    Abstract This article has no abstract. More >

  • Open Access

    SHORT COMMUNICATION

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

    Song Lu1, Jianjun Guo2, Richard Ansah Herman1, Xinyi Wu1, Lin Ma1, Guohua Wu1,*

    Journal of Renewable Materials, Vol.12, No.6, pp. 1043-1055, 2024, DOI:10.32604/jrm.2024.051767 - 02 August 2024

    Abstract Silk is widely used in the production of high-quality textiles. At the same time, the amount of silk textiles no longer in use and discarded is increasing, resulting in significant waste and pollution. This issue is of great concern in many countries where silk is used. Hydrogen peroxide as a naturally occurring compound is an important indicator of detection in both biology and the environment. This study aims to develop a composite fiber with hydrogen peroxide-sensing properties using discarded silk materials. To achieve this goal, firstly, polydopamine (PDA) was used to encapsulate the ZnFeO NPs… More > Graphic Abstract

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

  • Open Access

    ARTICLE

    Physiological and Biochemical Responses of Perennial Ryegrass Mixed Planting with Legumes under Heavy Metal Pollution

    Yi Xi, Li Zhang, Yanhong Xu, Wei Cheng, Chao Chen*

    Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1749-1765, 2024, DOI:10.32604/phyton.2024.051793 - 30 July 2024

    Abstract In artificially controlled pot experiments, perennial ryegrass was mixed with other leguminous plants (white clover and alfalfa) and treated with lead, zinc and cadmium (337 mg·kg, 648 mg·kg, and 9 mg·kg, respectively) to simulate compound pollution conditions. The results showed that the concentrations of heavy metals, transport factors, and bioconcentration factors in mixed planting of ryegrass decreased compared with those in monoculture. Regardless of whether heavy metal pollution was introduced, mixed planting increased the aboveground and underground biomasses of ryegrass. The different mixed planting treatments had no significant impact on the chlorophyll concentration of ryegrass.… More >

  • Open Access

    ARTICLE

    Synergism of Zinc Oxide/Organoclay-Loaded Poly(lactic acid) Hybrid Nanocomposite Plasticized by Triacetin for Sustainable Active Food Packaging

    Ponusa Songtipya1,2,*, Thummanoon Prodpran1,2, Ladawan Songtipya1,2, Theerarat Sengsuk1

    Journal of Renewable Materials, Vol.12, No.5, pp. 951-967, 2024, DOI:10.32604/jrm.2024.049068 - 17 July 2024

    Abstract The synergistic effect of organoclay (OC) and zinc oxide (ZnO) nanoparticles on the crucial properties of poly(lactic acid) (PLA) nanocomposite films was systematically investigated herein. After their incorporation into PLA via the solvent casting technique, the water vapor barrier property of the PLA/OC/ZnO film improved by a maximum of 86% compared to the neat PLA film without the deterioration of Young’s modulus or the tensile strength. Moreover, the film’s self-antibacterial activity against foodborne pathogens, including gram-negative (Escherichia coli, E. coli) and gram-positive (Staphylococcus aureus, S. aureus) bacteria, was enhanced by a maximum of approximately 98–99% compared to the neat… More > Graphic Abstract

    Synergism of Zinc Oxide/Organoclay-Loaded Poly(lactic acid) Hybrid Nanocomposite Plasticized by Triacetin for Sustainable Active Food Packaging

  • Open Access

    ARTICLE

    Long non-coding RNA-ATB induces trastuzumab resistance and aggravates the progression of gastric cancer by repressing miR- 200c via ZNF217 elevation

    JIAZHUANG LI*, WEI ZHANG, SHOUBAO GAO, LI SUN, QINGYANG TAI, YING LIU

    BIOCELL, Vol.47, No.10, pp. 2313-2320, 2023, DOI:10.32604/biocell.2023.029860 - 08 November 2023

    Abstract Background: Trastuzumab resistance accounts for chemotherapy failure in gastric cancer patients in clinical practice. The significance of long non-coding RNAs (lncRNAs) in the maintenance of drug resistance in gastric cancer has been already underlined. Method: This study aimed to identify the specific role of lncRNA-ATB in gastric cancer progression and trastuzumab resistance. The downstream miRs of lncRNA-ATB and target genes of miRs were predicted by bioinformatics analysis and verified using dual luciferase reporter assay. Loss- and gain-function assays were performed to explore the roles of lncRNA-ATB, miR-200c, and zinc-finger protein 217 (ZNF217) in the cell functions More >

  • Open Access

    ARTICLE

    Zinc alpha 2 glycoprotein (ZAG): A potential novel pharmacological target in diabetic retinopathy

    UMAPATHY PRAKASH1, SUBRAMANIAM RAJESH BHARATHIDEVI1,*, RAMYA R. NADIG2, RAJIV RAMAN2, GIRISH SHIV RAO2, MUNA BHENDE2

    BIOCELL, Vol.47, No.7, pp. 1473-1482, 2023, DOI:10.32604/biocell.2023.027804 - 21 June 2023

    Abstract Zinc alpha 2 glycoprotein (ZAG) is a 41 KDa secretory soluble glycoprotein found in different body fluids like the serum, saliva, sweat, breast milk, and urine. It is also found in tissues like the testis, epididymis, kidney, spleen, liver, lungs, heart, and brain. ZAG is an adipokine with multiple roles, including lipid mobilization, modulating glucose metabolisms, improving insulin sensitivity, inhibiting tumor proliferation through RNAse activity, and suppressing inflammation. Low levels of zinc and ZAG are linked to metabolic syndrome and are also reported as potential biomarkers for diabetic nephropathy. Interestingly zinc has been found to More >

  • Open Access

    ARTICLE

    The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription

    NING AN1,#, HEQING PENG2,#, MIN HOU3, DUOFENG SU2, LIU WANG4, XIAOGANG SHEN5,*, MING ZHANG1,*

    Oncology Research, Vol.31, No.3, pp. 307-316, 2023, DOI:10.32604/or.2023.028564 - 22 May 2023

    Abstract Zinc-finger proteins play different roles in cancer; however, the function of zinc-finger protein ZNF575 in cancer remains unclear. In the present study, we aimed to determine the function and expression of ZNF575 in colorectal cancer. Proliferation assay, colony formation assay, and tumor model in mice were used to investigate the function of ZNF575 after ectopic expression of ZNF575 in colorectal cancer (CRC) cells. RNA sequencing, ChIP, and luciferase assays were used to investigate the mechanism behind ZNF575 regulation of CRC cell growth. The expression of ZNF575 was determined by IHC staining in 150 pairs of… More > Graphic Abstract

    The zinc figure protein ZNF575 impairs colorectal cancer growth via promoting p53 transcription

  • Open Access

    ARTICLE

    Response of Contrasting Rice Genotypes to Zinc Sources under Saline Conditions

    Muhammad Jan1,*, Muhammad Anwar-Ul-Haq2, Talha Javed3, Sadam Hussain4,*, Ilyas Ahmad5, Muhammad Ashraf Sumrah6, Javed Iqbal7, Babar Hussain Babar8, Aqsa Hafeez9, Muhammad Aslam5, Muhammad Tahir Akbar10, Marjan Aziz6, Khadiga Alharbi11, Izhar Ullah12

    Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1361-1375, 2023, DOI:10.32604/phyton.2023.026620 - 09 March 2023

    Abstract Abiotic stresses are among the major limiting factors for plant growth and crop productivity. Among these, salinity is one of the major risk factors for plant growth and development in arid to semi-arid regions. Cultivation of salt tolerant crop genotypes is one of the imperative approaches to meet the food demand for increasing population. The current experiment was carried out to access the performance of different rice genotypes under salinity stress and Zinc (Zn) sources. Four rice genotypes were grown in a pot experiment and were exposed to salinity stress (7 dS m−1), and Zn (15… More >

  • Open Access

    ARTICLE

    Expression and function of long non-coding RNA DLX6-AS1 in endometrial cancer

    WEI SHI1,2,3,#, JIANXIA LIN1,2,3,#, RONG JIN1,2,3, XIANJING XIE1,2,3, YAN LIANG1,2,3,*

    BIOCELL, Vol.47, No.4, pp. 869-877, 2023, DOI:10.32604/biocell.2023.026037 - 08 March 2023

    Abstract Background: LncRNA DLX6-AS1 has been uncovered to exert effects on various cancers. Nevertheless, the impacts of DLX6-AS1 on endometrial cancer (EC) development remained obscure. The study explored the influence of DLX6-AS1 on EC progression via the microRNA (miR)-374a-3p/zinc-finger protein (ZFX) axis.Methods: EC cell lines were collected and DLX6-AS1, miR-374a-3p, and ZFX levels in EC cell lines were detected. The EC cells were transfected with DLX6-AS1, miR-374a-3p, and ZFX constructs to examine the biological functions of EC cells. The xenograft model was established for detecting tumor growth. Rescue experiments were conducted to verify the interaction of DLX6-AS1, More > Graphic Abstract

    Expression and function of long non-coding RNA DLX6-AS1 in endometrial cancer

  • Open Access

    ARTICLE

    Facile Preparation of Dopamine-Modified Magnetic Zinc Ferrite Immobilized Lipase for Highly Efficient Synthesis of OPO Functional Lipid

    Xue Huang1,*, Zeyu Chen1, Ruizhao Yang1, Guangzhu Feng2

    Journal of Renewable Materials, Vol.11, No.5, pp. 2301-2319, 2023, DOI:10.32604/jrm.2023.025888 - 13 February 2023

    Abstract 1,3-Dioleoyl-2-palmitoylglycerol (OPO) has been a hotspot of functional oils research in recent years, but due to the high cost of sn-1,3 specific lipase in enzymatic synthesis and the lack of biocatalyst stability, large-scale industrial application is difficult. In this study, the prepared magnetic ZnFe2O4 was functionalized with dopamine to obtain ZnFe2O4@PDA, and the nano-biocatalyst ZnFe2O4@PDA@RML was prepared by immobilizing sn-1,3 specific lipase of Rhizomucor miehei lipase (RML) via a cross-linking method. The existence of RML on ZnFe2O4@PDA was confirmed by XRD, FTIR, SEM, and TEM. This strategy proved to be simple and effective because the lipase immobilized on… More > Graphic Abstract

    Facile Preparation of Dopamine-Modified Magnetic Zinc Ferrite Immobilized Lipase for Highly Efficient Synthesis of OPO Functional Lipid

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