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  • Open Access

    ARTICLE

    A Study on Outlier Detection and Feature Engineering Strategies in Machine Learning for Heart Disease Prediction

    Varada Rajkumar Kukkala1, Surapaneni Phani Praveen2, Naga Satya Koti Mani Kumar Tirumanadham3, Parvathaneni Naga Srinivasu4,5,*

    Computer Systems Science and Engineering, Vol.48, No.5, pp. 1085-1112, 2024, DOI:10.32604/csse.2024.053603 - 13 September 2024

    Abstract This paper investigates the application of machine learning to develop a response model to cardiovascular problems and the use of AdaBoost which incorporates an application of Outlier Detection methodologies namely; Z-Score incorporated with Grey Wolf Optimization (GWO) as well as Interquartile Range (IQR) coupled with Ant Colony Optimization (ACO). Using a performance index, it is shown that when compared with the Z-Score and GWO with AdaBoost, the IQR and ACO, with AdaBoost are not very accurate (89.0% vs. 86.0%) and less discriminative (Area Under the Curve (AUC) score of 93.0% vs. 91.0%). The Z-Score and GWO… More >

  • Open Access

    REVIEW

    Z-Score in Fetal Echocardiography–Is there Still Room for New Studies?

    Marcio Fragoso Vieira1,2, Nathalie Jeanne Bravo-Valenzuela3, Edward Araujo Júnior1,*

    Congenital Heart Disease, Vol.19, No.3, pp. 305-314, 2024, DOI:10.32604/chd.2024.053484 - 26 July 2024

    Abstract Congenital heart disease (CHD) is the most common type of birth defect, representing a significant cause of perinatal morbidity and mortality. Early diagnosis of such anomalies is crucial for improving outcomes. Current protocols recommend a qualitative assessment of cardiac structures using two-dimensional ultrasound (2DUS) and color Doppler imaging. In cases of suspected abnormalities, quantitative assessments through cardiac structure measurements and reference curves can aid in accurate diagnosis. Similar to centiles widely employed in obstetrics, Z-scores provide more precise quantification of various cardiac structures, particularly at the extremes of the curve. While the development of reference More >

  • Open Access

    ARTICLE

    Fetal heart size measurements as new predictors of homozygous α-thalassemia-1 in mid-pregnancy

    Xinyan Li1, Xiaoxia Qiu1, Huan Huang1, Yili Zhao2, Xueqin Li1, Meng Li1, Xiaoxian Tian1

    Congenital Heart Disease, Vol.13, No.2, pp. 282-287, 2018, DOI:10.1111/chd.12568

    Abstract Objective: To evaluate the efficacy of using fetal heart size measurements derived from axial echocardiography to predict homozygous α-thalassemia-1.
    Design: Prospective diagnostic study.
    Setting: The carrier rate of α-thalassemia-1 (–/αα) in China’s Guangxi Zhuang Autonomous Region is approximately 15%. If both parents are carriers, the risk of homozygous a-thalassemia-1 in one pregnancy is 25%.
    Patients: Singleton mid-pregnancies at risk of homozygous α-thalassemia-1 were enrolled.
    Outcome Measures: Fetal heart measurements, including heart diameter (HD), heart length (HL), heart circumference (HC), and heart area (HA), were measured. The z-scores for these heart parameters were then calculated separately based on previously constructed z-score… More >

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