Oncology Research Editorial Office

Oncology Research, Vol.32, No.8, pp. 1381-1381, 2024, DOI:10.32604/or.2024.055035

Abstract This article has no abstract. More >

Oncology Research Editorial Office

Oncology Research, Vol.32, No.8, pp. 1377-1377, 2024, DOI:10.32604/or.2024.055033

Abstract This article has no abstract. More >

DIMITRA P. VAGELI^1,2,*, PANAGIOTIS G. DOUKAS³, KERASIA GOUPOU², ANTONIOS D. BENOS², KYRIAKI ASTARA^2,4, KONSTANTINA ZACHAROULI², SOTIRIS SOTIRIOU⁵, MARIA IOANNOU²

Oncology Research, Vol.32, No.8, pp. 1239-1256, 2024, DOI:10.32604/or.2024.052130

Abstract Glioblastoma multiforme (GBM) is an aggressive primary brain tumor characterized by extensive heterogeneity and vascular proliferation. Hypoxic conditions in the tissue microenvironment are considered a pivotal player leading tumor progression. Specifically, hypoxia is known to activate inducible factors, such as hypoxia-inducible factor 1alpha (HIF-1α), which in turn can stimulate tumor neo-angiogenesis through activation of various downward mediators, such as the vascular endothelial growth factor (VEGF). Here, we aimed to explore the role of HIF-1α/VEGF immunophenotypes alone and in combination with other prognostic markers or clinical and image analysis data, as potential biomarkers of GBM prognosis… More >

WEI JIANG¹, MEI ZHOU^2,*

Oncology Research, Vol.32, No.8, pp. 1359-1368, 2024, DOI:10.32604/or.2024.043423

Abstract Multiple myeloma (MM) is a plasma cell malignancy and remains incurable as it lacks effective curative approaches; thus, novel therapeutic strategies are desperately needed. The study aimed to explore the therapeutic role of dihydromyricetin (DHM) in MM and explore its mechanisms. Human MM and normal plasma samples, human MM cell lines, and normal plasma cells were used for in vitro experiments. Cell counting kit-8 (CCK-8), flow cytometry, and trans-well assays were performed for the assessment of cell viability, apoptosis, migration, and invasion, respectively. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to assess the mRNA expression… More > Graphic Abstract

Md. Parvez Anwar^*, Masuma Akhter, Sharmin Aktar, Sinthia Afsana Kheya, A. K. M. Mominul Islam^*, Sabina Yeasmin, Ahmed Khairul Hasan, Md. Harun Or Rashid

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1159-1177, 2024, DOI:10.32604/phyton.2024.049073

Abstract Seed priming is a pre-germinated technique that can enhance seed germination percentage, faster and synchronized germination, better seedling growth, and yield under stress conditions. To ascertain the most effective seed priming method that would ensure the potential yield of wheat in Bangladesh, two experiments were carried out from December 2021 to March 2022 at the Department of Agronomy, Bangladesh Agricultural University. Two wheat varieties namely BARI Gom-28 and BWMRI Gom-1 were subjected to a range of priming chemicals in both lab and pot tests. These compounds included the following: control (no priming), hydropriming (distilled water),… More >

Abdul Momin¹, Amana Khatoon^1,*, Wajahat Khan¹, Dilsat Bozdoğan Konuşkan², Muhammad Mudasar Aslam³, Muhammad Jamil⁴, Shafiq Ur Rehman⁵, Baber Ali⁶, Alevcan Kaplan⁷, Sana Wahab⁸, Muhammad Nauman Khan^9,*, Sezai Ercisli^10,11, Mohammad Khalid Al-Sadoon¹²

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1117-1128, 2024, DOI:10.32604/phyton.2024.048994

Abstract Sprouts are ready-to-eat and are recognized worldwide as functional components of the human diet. Recent advances in innovative agricultural techniques could enable an increase in the production of healthy food. The use of light-emitting diode (LED) in indoor agricultural production could alter the biological feedback loop, increasing the functional benefits of plant foods such as wheat and lentil sprouts and promoting the bioavailability of nutrients. The effects of white (W), red (R), and blue (B) light were investigated on the growth parameters and nutritional value of wheat and lentil sprouts. In the laboratory, seeds were… More >

Lili Bai^1,*, Wenhui Li¹, He Ren^1,2, Feng Li¹, Tao Yan¹, Lirong Chen³

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4513-4531, 2024, DOI:10.32604/cmc.2024.051348

Abstract Addressing the challenges posed by the nonlinear and non-stationary vibrations in rotating machinery, where weak fault characteristic signals hinder accurate fault state representation, we propose a novel feature extraction method that combines the Flexible Analytic Wavelet Transform (FAWT) with Nonlinear Quantum Permutation Entropy. FAWT, leveraging fractional orders and arbitrary scaling and translation factors, exhibits superior translational invariance and adjustable fundamental oscillatory characteristics. This flexibility enables FAWT to provide well-suited wavelet shapes, effectively matching subtle fault components and avoiding performance degradation associated with fixed frequency partitioning and low-oscillation bases in detecting weak faults. In our approach,… More >

Tengfei Li¹, Wenhui Zhang¹, Ke Mi¹, Qingming Lin¹, Shuangwei Zhao^2,*, Jiayi Song²

Energy Engineering, Vol.121, No.7, pp. 1991-2007, 2024, DOI:10.32604/ee.2024.049460

Abstract Aiming at the problem of energy storage unit failure in the spring operating mechanism of low voltage circuit breakers (LVCBs). A fault diagnosis algorithm based on an improved Sparrow Search Algorithm (ISSA) optimized Backpropagation Neural Network (BPNN) is proposed to improve the operational safety of LVCB. Taking the 1.5kV/4000A/75kA LVCB as an example. According to the current operating characteristics of the energy storage motor, fault characteristics are extracted based on Empirical Wavelet Transform (EWT). Traditional BPNN has problems such as difficulty adjusting network weights and thresholds, being sensitive to initial weights, and quickly falling into More >

Fu-qiang Zhu^*1, Li Zeng^†1, Na Tang^*, Ya-ping Tang^‡, Bo-ping Zhou^*, Fang-fang Li^*, Wei-gang Wu^*, Xiao-bing Zeng^*, Shu-song Peng^*

Oncology Research, Vol.24, No.6, pp. 415-427, 2016, DOI:10.3727/096504016X14685034103473

Abstract Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin’s lymphoma in the adult population, and treatment of DLBCL is still unfavorable. Therefore, there is an urgent requirement to investigate the molecular mechanisms underlying DLBCL tumorigenesis. To study the potential function of microRNA-155 (miR-155) involved in the regulation of lymphoma, we monitored lymphoma cell behavior including proliferation, cell cycle, and apoptosis using CCK-8 and flow cytometry analysis. Real-time PCR was used to detect the expression levels of miR-155 in 118 lymphoma patients’ tissues, and Western blot was also used to analyze the expression level of… More >

Min Zhao^*, Zhiying Su^†, Shiyang Zhang^‡, Liangjin Zhuang^§, Yudi Xie^*, Xiaodong Li^*

Oncology Research, Vol.24, No.5, pp. 353-360, 2016, DOI:10.3727/096504016X14685034103275

Abstract Ovarian cancer (OC) is one of the most common gynecological malignancies. MicroRNAs (miRs) play a crucial role in the development and progression of OC, but the underlying mechanism remains largely unclear. Our study investigated the regulatory role of miR-148a in OC cell proliferation and invasion. We found that miR- 148a was significantly downregulated in OC tissues compared to their matched adjacent nontumor tissues. In addition, its expression was also reduced in OC cell lines (SKOV3, ES-2, OVCAR, and A2780) compared to normal ovarian epithelial cells. Overexpression of miR-148a caused a significant decrease in OC cell… More >