Xiaorui Zhang^1,2,*, Wenzheng Zhang², Wei Sun³, Hailun Wu², Aiguo Song⁴, Sunil Kumar Jha⁵

Computer Systems Science and Engineering, Vol.43, No.1, pp. 1-15, 2022, DOI:10.32604/csse.2022.024950 - 23 March 2022

Abstract Telemedicine plays an important role in Corona Virus Disease 2019 (COVID-19). The virtual surgery simulation system, as a key component in telemedicine, requires to compute in real-time. Therefore, this paper proposes a real-time cutting model based on finite element and order reduction method, which improves the computational speed and ensure the real-time performance. The proposed model uses the finite element model to construct a deformation model of the virtual lung. Meanwhile, a model order reduction method combining proper orthogonal decomposition and Galerkin projection is employed to reduce the amount of deformation computation. In addition, the More >

Xiaorui Zhang^1,2,*, Tong Xu¹, Wei Sun², Jiali Duan¹, Sunil Kumar Jha³

CMC-Computers, Materials & Continua, Vol.69, No.1, pp. 727-745, 2021, DOI:10.32604/cmc.2021.018182 - 04 June 2021

Abstract In the simulation of acupuncture manipulation, it is necessary to accurately capture the information of acupuncture points and particles around them. Therefore, a soft tissue modeling method that can accurately track model particles is needed. In this paper, a soft tissue acupuncture model based on the mass-spring force net is designed. MSM is used as the auxiliary model and the SHF model is combined. SHF is used to establish a three-layer soft tissue model of skin, fat, and muscle, and a layer of the MSM based force network is covered on the surface of soft More >

Xiaorui Zhang^1,2,*, Jiali Duan¹, Wei Sun², Tong Xu¹, Sunil Kumar Jha³

CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.1, pp. 117-133, 2021, DOI:10.32604/cmes.2021.012034 - 30 March 2021

Abstract The cutting simulation of soft tissue is important in virtual surgery. It includes three major challenges in computation: Soft tissue simulation, collision detection, and handling, as well as soft tissue models. In order to address the earlier challenges, we propose a virtual cutting system based on the mass-spring model. In this system, MSM is utilized to simulate the soft tissue model. Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting. Second, a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft More >

Xiaorui Zhang^1,2,*, Xuefeng Yu¹, Wei Sun², Aiguo Song³

CMES-Computer Modeling in Engineering & Sciences, Vol.124, No.3, pp. 1131-1147, 2020, DOI:10.32604/cmes.2020.09735 - 21 August 2020

Abstract In order to solve the problem of high computing cost and low simulation accuracy caused by discontinuity of incision in traditional meshless model, this paper proposes a soft tissue deformation model based on the Marquardt algorithm and enrichment function. The model is based on the element-free Galerkin method, in which Kelvin viscoelastic model and adjustment function are integrated. Marquardt algorithm is applied to fit the relation between force and displacement caused by surface deformation, and the enrichment function is applied to deal with the discontinuity in the meshless method. To verify the validity of the More >

Dalin Tang^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 11-11, 2019, DOI:10.32604/mcb.2019.05170

Abstract Medical imaging and image-based modeling have made considerable progress in recent years in cardiovascular research, such as identifying atherosclerotic plaque morphological and mechanical risk factors which may be used in developing improved patient screening strategies, and performing virtual heart surgery seeking optimal surgical procedures for best post-surgical outcome. We will report recent progress in using multi-modality image-based models to predict vulnerable plaque progression and vulnerability change. In particular, we will report our recent results using IVUS+OCT data to obtain more accurate stress/strain calculations. Inflammation and cap erosion will affect cap material properties. If OCT image… More >

Xiaorui Zhang^1,2,3,*, Jiali Duan¹, Jia Liu², Norman I. Badler³

CMC-Computers, Materials & Continua, Vol.60, No.3, pp. 1055-1071, 2019, DOI:10.32604/cmc.2019.03915

Abstract Current research on suture simulation mainly focus on the construction of suture line, and existing suture simulation systems still need to be improved in terms of diversity, soft tissue effects, and stability. This paper presents an integrated liver suture surgery system composed of three consecutive suture circumstances, which is conducive to liver suture surgery training. The physically-based models used in this simulation are based on different mass-spring models regulated by a special constrained algorithm, which can improve the model accuracy, and stability by appropriately restraining the activity sphere of the surrounding mass nodes around the… More >

Weiguang Yang¹, Frank L. Hanley², Frandics P. Chan³, Alison L. Marsden^1,4, Irene E. Vignon-Clementel⁵, Jeffrey A. Feinstein^1,4

Congenital Heart Disease, Vol.13, No.2, pp. 241-250, 2018, DOI:10.1111/chd.12556

Abstract Background: Up to 90% of individuals with Alagille syndrome have congenital heart diseases. Peripheral pulmonary artery stenosis (PPS), resulting in right ventricular hypertension and pulmonary flow disparity, is one of the most common abnormalities, yet the hemodynamic effects are illdefined, and optimal patient management and treatment strategies are not well established. The purpose of this pilot study is to use recently refined computational simulation in the setting of multiple surgical strategies, to examine the influence of pulmonary artery reconstruction on hemodynamics in this population.
Materials and Methods: Based on computed tomography angiography and cardiac catheterization data, preoperative… More >

Zhedian Zhou¹, Tal Geva², Rahul H. Rathod², Alexander Tang², Chun Yang³, Kristen L. Billiar⁴, Dalin Tang^1,*,3, Pedro del Nido⁵

Molecular & Cellular Biomechanics, Vol.15, No.2, pp. 99-115, 2018, DOI:10.3970/mcb.2018.00558

Abstract Patients with repaired Tetralogy of Fallot (ToF), a congenital heart defect which includes a ventricular septal defect and severe right ventricular outflow obstruction, account for the majority of cases with late onset right ventricle (RV) failure. The current surgical approach, which includes pulmonary valve replacement/insertion (PVR), has yielded mixed results. A computational parametric study using 7 patient-specific RV/LV models based on cardiac magnetic resonance (CMR) data as "virtual surgery" was performed to investigate the impact of patch size, RV remodeling and tissue regeneration in PVR surgery design on RV cardiac functions. Two patch sizes, three… More >