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  • Open Access

    ARTICLE

    Quantitative Parameters Analysis for Prenatally Echocardiographic Diagnosis of Atrioventricular Septal Defects

    Xiaoxue Zhou1, Tingyang Yang2, Ye Zhang1, Yanping Ruan1, Jiancheng Han1, Xiaowei Liu1, Ying Zhao1, Xiaoyan Gu1, Tingting Liu1, Hairui Wang1, Yihua He1,*

    Congenital Heart Disease, Vol.18, No.3, pp. 387-397, 2023, DOI:10.32604/chd.2023.029060 - 09 June 2023

    Abstract Background: Atrioventricular septal defects (AVSDs) are screened and diagnosed usually rely on the imaging characteristics of fetal echocardiography (FE). However, diagnosis on images is heavily depended on sonographers’ experience and the quantitative data are rarely studied. Objective: This study aimed to realize the prenatal diagnosis of AVSDs by analyzing the quantitative data on FE. Methods: One hundred and thirteen cardiac quantitative data was analyzed in 370 normal and 49 AVSDs fetuses retrospectively. The top six with the highest diagnostic accuracy rate were acquired according to the area under the curve (AUC), and the diagnostic value of… More >

  • Open Access

    ARTICLE

    Effectiveness and Safety of Transcatheter Closure of Various Ventricular Septal Defects Using Second-Generation Amplatzer Duct Occluders

    Jianming Wang, Qiguang Wang*, Xiaotang Sheng, Jingsong Geng, Jiawang Xiao, Xianyang Zhu*

    Congenital Heart Disease, Vol.18, No.2, pp. 183-195, 2023, DOI:10.32604/chd.2022.021855 - 15 March 2023

    Abstract Objective: This study was designed to determine the long-term safety and efficacy of using the Amplatzer Duct Occluder II (ADO II) for the closure of various ventricular septal defects (VSDs). Methods: From January 2011 to December 2019, selected VSD patients were treated through transcatheter intervention using ADO II occluders. The closure results and complications from 188 patients, involving 167 perimembranous ventricular septal defects (pmVSDs), 9 intracristal VSDs, 11 post surgery residual shunts and 1 post closure residual shunt with the mean outlet diameter3.1 ± 0.8 mm under angiography, were enrolled in this study. Results: The success rate… More >

  • Open Access

    ARTICLE

    Percutaneous closure of perimembranous ventricular septal defects utilizing almost ideal Amplatzer Duct Occluder II: Why limitation in sizes?

    Anoosh Esmaeili, Kachina Behnke‐Hall, Roland Schrewe, Dietmar Schranz

    Congenital Heart Disease, Vol.14, No.3, pp. 389-395, 2019, DOI:10.1111/chd.12731

    Abstract Aim: The purpose of this study is to describe the special aspects of perimembranous ventricular septal defects (pmVSD) closure by utilizing Amplatzer Duct Occluder II (ADO II) devices with a rational request for bigger ADO‐II sizes, based on our experi‐ ence in transcatheter device closure of pmVSD.
    Methods and Results: At our institution, placement of an ADO II device was used in 15 patients with pmVSD; the patients’ age ranged between 6 months and 20 years. The indications for closure were CHF (n = 4), hemodynamically significant shunt (n = 7), tricuspid regurgitation (n = 3), and… More >

  • Open Access

    ARTICLE

    Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up

    Alberto Cresti1, Raffaele Giordano2, Martin Koestenberger3, Isabella Spadoni4, Marco Scalese5, Ugo Limbruno1, Susanna Falorini6, Stefania Stefanelli1, Andrea Picchi1, Francesco De Sensi1, Angela Malandrino7, Massimiliano Cantinotti4,5

    Congenital Heart Disease, Vol.13, No.1, pp. 105-112, 2018, DOI:10.1111/chd.12528

    Abstract Background: Despite ventricular septal defects (VSDs) are the most common congenital heart diseases (CHDs) in the neonatal period, their incidence and natural history are still debated and their follow-up and management strategies remain controversial. Our aim was to evaluate the incidence and natural history of isolated VSDs.
    Methods: From January 1996 to December 2015 all neonates with a CHD suspicion were referred to the Cardiological Department of Grosseto Misericordia Hospital. Only newborns with confirmed isolated VSD were enrolled in this study and followed for 6 years.
    Results: Our 343 newborns with an isolated VSD (incidence of 10.45/1000/births) account… More >

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