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  • Open Access

    REVIEW

    mRNA vaccines: a new era in vaccine development

    SHUBHRA CHANDRA1,2, JENNIFER C. WILSON1,2, DAVID GOOD3, MING Q. WEI1,2,*

    Oncology Research, Vol.32, No.10, pp. 1543-1564, 2024, DOI:10.32604/or.2024.043987 - 18 September 2024

    Abstract The advent of RNA therapy, particularly through the development of mRNA cancer vaccines, has ushered in a new era in the field of oncology. This article provides a concise overview of the key principles, recent advancements, and potential implications of mRNA cancer vaccines as a groundbreaking modality in cancer treatment. mRNA cancer vaccines represent a revolutionary approach to combatting cancer by leveraging the body’s innate immune system. These vaccines are designed to deliver specific mRNA sequences encoding cancer-associated antigens, prompting the immune system to recognize and mount a targeted response against malignant cells. This personalized… More > Graphic Abstract

    mRNA vaccines: a new era in vaccine development

  • Open Access

    REVIEW

    Molecular basis of COVID-19, ARDS and COVID-19-associated ARDS: Diagnosis pathogenesis and therapeutic strategies

    PRIYADHARSHINI THANJAVUR SRIRAMAMOORTHI1,2, GAYATHRI GOPAL1,2, SHIBI MURALIDAR1,2, SAI RAMANAN ESWARAN1,2, DANUSH NARAYAN PANNEERSELVAM1,2, BHUVANESWARAN MEIYANATHAN1,2, SRICHANDRASEKAR THUTHIKKADU INDHUPRAKASH1,2, SENTHIL VISAGA AMBI1,2,*

    BIOCELL, Vol.47, No.11, pp. 2335-2350, 2023, DOI:10.32604/biocell.2023.029379 - 27 November 2023

    Abstract The novel coronavirus pneumonia (COVID-19) is spreading worldwide and threatening people greatly. The routes by which SARS-CoV-2 causes lung injury have grown to be a major concern in the scientific community since patients with new Coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2) have a high likelihood of developing acute respiratory distress syndrome (ARDS) in severe cases. The mortality rate of COVID-19 has increased over the period due to rapid spread, and it becomes crucial to understand the disease epidemiology, pathogenic mechanisms, and suitable treatment strategies. ARDS is a respiratory disorder and is one of the… More > Graphic Abstract

    Molecular basis of COVID-19, ARDS and COVID-19-associated ARDS: Diagnosis pathogenesis and therapeutic strategies

  • Open Access

    ARTICLE

    Fake News Encoder Classifier (FNEC) for Online Published News Related to COVID-19 Vaccines

    Asma Qaiser1, Saman Hina1, Abdul Karim Kazi1,*, Saad Ahmed2, Raheela Asif3

    Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 73-90, 2023, DOI:10.32604/iasc.2023.036784 - 29 April 2023

    Abstract In the past few years, social media and online news platforms have played an essential role in distributing news content rapidly. Consequently. verification of the authenticity of news has become a major challenge. During the COVID-19 outbreak, misinformation and fake news were major sources of confusion and insecurity among the general public. In the first quarter of the year 2020, around 800 people died due to fake news relevant to COVID-19. The major goal of this research was to discover the best learning model for achieving high accuracy and performance. A novel case study of More >

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