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  • Open Access

    ARTICLE

    IQAOA for Two Routing Problems: A Methodological Contribution with Application to TSP and VRP

    Eric Bourreau1, Gérard Fleury2, Philippe Lacomme2,*

    Journal of Quantum Computing, Vol.6, pp. 25-51, 2024, DOI:10.32604/jqc.2024.048792 - 25 October 2024

    Abstract The paper presents a novel quantum method for addressing two fundamental routing problems: the Traveling Salesman Problem (TSP) and the Vehicle Routing Problem (VRP), both central to routing challenges. The proposed method, named the Indirect Quantum Approximate Optimization Algorithm (IQAOA), leverages an indirect solution representation using ranking. Our contribution focuses on two main areas: 1) the indirect representation of solutions, and 2) the integration of this representation into an extended version of QAOA, called IQAOA. This approach offers an alternative to QAOA and includes the following components: 1) a quantum parameterized circuit designed to simulate… More >

  • Open Access

    ARTICLE

    Advanced Machine Learning Methods for Prediction of Blast-Induced Flyrock Using Hybrid SVR Methods

    Ji Zhou1,2, Yijun Lu3, Qiong Tian1,2, Haichuan Liu3, Mahdi Hasanipanah4,5,*, Jiandong Huang3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1595-1617, 2024, DOI:10.32604/cmes.2024.048398 - 20 May 2024

    Abstract Blasting in surface mines aims to fragment rock masses to a proper size. However, flyrock is an undesirable effect of blasting that can result in human injuries. In this study, support vector regression (SVR) is combined with four algorithms: gravitational search algorithm (GSA), biogeography-based optimization (BBO), ant colony optimization (ACO), and whale optimization algorithm (WOA) for predicting flyrock in two surface mines in Iran. Additionally, three other methods, including artificial neural network (ANN), kernel extreme learning machine (KELM), and general regression neural network (GRNN), are employed, and their performances are compared to those of four More >

  • Open Access

    ARTICLE

    Vaccinia-related kinase 2 variants differentially affect breast cancer growth by regulating kinase activity

    SEUNG-HEE GWAK1, JUHYUN LEE1, EUNJI OH1, DOHYUN LEE1,2, WONSHIK HAN3, JONGMIN KIM1,*, KYONG-TAI KIM4,*

    Oncology Research, Vol.32, No.2, pp. 421-432, 2024, DOI:10.32604/or.2023.031031 - 28 December 2023

    Abstract Genetic information is transcribed from genomic DNA to mRNA, which is then translated into three-dimensional proteins. mRNAs can undergo various post-transcriptional modifications, including RNA editing that alters mRNA sequences, ultimately affecting protein function. In this study, RNA editing was identified at the 499th base (c.499) of human vaccinia-related kinase 2 (VRK2). This RNA editing changes the amino acid in the catalytic domain of VRK2 from isoleucine (with adenine base) to valine (with guanine base). Isoleucine-containing VRK2 has higher kinase activity than the valine-containing VRK2, which leads to an increase in tumor cell proliferation. Earlier we… More > Graphic Abstract

    Vaccinia-related kinase 2 variants differentially affect breast cancer growth by regulating kinase activity

  • Open Access

    ARTICLE

    System Energy and Efficiency Analysis of 12.5 W VRFB with Different Flow Rates

    Kehuan Xie1, Longhai Yu2,3, Chuanchang Li1,*

    Energy Engineering, Vol.120, No.12, pp. 2903-2915, 2023, DOI:10.32604/ee.2023.027636 - 29 November 2023

    Abstract Vanadium redox flow battery (VRFB) is considered one of the most potential large-scale energy storage technologies in the future, and its electrolyte flow rate is an important factor affecting the performance of VRFB. To study the effect of electrolyte flow rate on the performance of VRFB, the hydrodynamic model is established and a VRFB system is developed. The results show that under constant current density, with the increase of electrolyte flow rate, not only the coulombic efficiency, energy efficiency, and voltage efficiency will increase, but also the capacity and energy discharged by VRFB will also More >

  • Open Access

    ARTICLE

    Les enjeux de l’identification et de la gestion des inégalités épistémiques dans les RISP : Illustration dans la conception et la mise en œuvre d’un dispositif d’ETP en oncologie

    Philippe Terral*, Charlotte Bruneau, Jean-Paul Génolini

    Psycho-Oncologie, Vol.17, No.3, pp. 181-189, 2023, DOI:10.32604/po.2023.044917 - 30 September 2023

    Abstract Objectif : La dynamique conjointe des savoirs (des bénéficiaires, intervenants, décideurs, chercheurs) et des pouvoirs (pouvoirs de paroles et d’actions, asymétries voire hiérarchies établies entre les individus et leurs savoirs) des personnes qui les portent au cœur des RISP, est analysée au prisme de la gestion des inégalités épistémiques. Nous étudions la nature des partages ou non partages de savoirs entre ces différentes catégories d’acteurs impliqués dans les interventions en santé. Méthode : La méthodologie qualitative s’appuie sur 36 entretiens et 6 années d’observations ethnographiques d’ateliers de conception ou de mise en œuvre d’un programme d’ETP, de… More >

  • Open Access

    ARTICLE

    Proposer un accompagnement au sevrage tabagique aux patients atteints de cancer : le rôle des associations proposant des soins de support. Exemple de la Ligue Contre le Cancer Gironde

    Océane Phanatzis1,2,*, Rébecca Ratel1,2, Isabelle Barcos1,2, Marie Daspas3, Emmanuelle Clairembault3, François Alla1,2

    Psycho-Oncologie, Vol.17, No.3, pp. 133-145, 2023, DOI:10.32604/po.2023.044916 - 30 September 2023

    Abstract Objectif : L’objectif de cet article est d’exposer les composantes interventionnelles et contextuelles d’un accompagnement au sevrage tabagique dans le cadre des soins oncologiques de support (SOS) délivrés par une association, qui soit viable en contexte français et efficace, et de décrire le processus de recherche partenariale dans lequel elles ont été élaborées. Méthodes : L’intervention a été développée à partir d’un ensemble de données recueillies lors d’une étude de viabilité à la mise en place d’une offre de sevrage tabagique au sein de la Ligue Contre le Cancer Gironde, une revue de la portée sur les… More >

  • Open Access

    ARTICLE

    Assessment of Nanoparticle-Enriched Solvents for Oil Recovery Enhancement

    Muayad M. Hasan1,*, Firas K. Al-Zuhairi2, Anfal H. Sadeq1, Rana A. Azeez1

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.11, pp. 2827-2835, 2023, DOI:10.32604/fdmp.2023.027746 - 18 September 2023

    Abstract Solvents are generally used to reduce the viscosity of heavy crude oil and ultimately enhance oil recovery. Recently, a new method has been introduced where nanoparticles (NPs) are exploited to induce enhanced oil recovery owing to their ability to improve the mobility ratio, dampen the interfacial tension, and alter rock wettability. This study investigated the integration of nano-alumina (Al2O3) NPs with an n-hexane solvent. In particular, a Brookfield viscometer has been used to measure the crude oil viscosity and it has been found that NPs can effectively lead to a significant decrease in the overall oil More >

  • Open Access

    ARTICLE

    Cloning and Functional Validation of Mung Bean VrPR Gene

    Xiaokui Huang1, Yingbin Xue1, Aaqil Khan1, Hanqiao Hu1, Naijie Feng1,2,*, Dianfeng Zheng1,2,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.8, pp. 2369-2382, 2023, DOI:10.32604/phyton.2023.027457 - 25 June 2023

    Abstract For the purpose of functional validation, the mung bean (Vigna radiata) VrPR gene was cloned and overexpressed in Arabidopsis thaliana. The findings revealed that the ORF of VrPR contained 1200 bp, in which 399 amino acids were encoded. Bioinformatics analysis showed that the VrPR protein belonged to the NADB Rossmann superfamily, which was one of the non-transmembrane hydrophilic proteins. VrPR was assumed to have 44 amino acid phosphorylation sites and be contained in chloroplasts. The VrPR secondary structure comprised of random coil, α helix, β angle, and extended chain, all of which were quite compatible with the anticipated tertiary structure. More >

  • Open Access

    ARTICLE

    Determination of AVR System PID Controller Parameters Using Improved Variants of Reptile Search Algorithm and a Novel Objective Function

    Baran Hekimoğlu*

    Energy Engineering, Vol.120, No.7, pp. 1515-1540, 2023, DOI:10.32604/ee.2023.029024 - 04 May 2023

    Abstract Two novel improved variants of reptile search algorithm (RSA), RSA with opposition-based learning (ORSA) and hybrid ORSA with pattern search (ORSAPS), are proposed to determine the proportional, integral, and derivative (PID) controller parameters of an automatic voltage regulator (AVR) system using a novel objective function with augmented flexibility. In the proposed algorithms, the opposition-based learning technique improves the global search abilities of the original RSA algorithm, while the hybridization with the pattern search (PS) algorithm improves the local search abilities. Both algorithms are compared with the original RSA algorithm and have shown to be highly… More > Graphic Abstract

    Determination of AVR System PID Controller Parameters Using Improved Variants of Reptile Search Algorithm and a Novel Objective Function

  • Open Access

    ARTICLE

    Acute Effects of Virtual Reality Exercise on Young Adults’ Blood Pressure and Feelings

    Pablo Saiz-Gonzalez1,2, Daniel J. McDonough3, Wenxi Liu4, Zan Gao1,*

    International Journal of Mental Health Promotion, Vol.25, No.5, pp. 711-719, 2023, DOI:10.32604/ijmhp.2023.027530 - 28 April 2023

    Abstract Virtual reality (VR) seems to have the potential to provide opportunities to promote physical activity (PA) in a fun way. This paper aimed to examine the acute effects of three different virtual reality-based exercise bikes on young adults’ blood pressure (BP) and feelings compared to a traditional exercise cycling session. Four exercise sessions (immersive VR cycling, two non-immersive VR cycling, and traditional cycling) were completed by 36 young adults (22 females; Mage = 23.6 years). BP was measured immediately before and after each session using a BP cuff and exercise-induced feelings were assessed via an established… More >

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