Piao Yongfeng^*†‡§1, Jiang Chuner^*¶#1, Wang Lei^*†‡§, Yan Fengqin^*†‡§, Ye Zhimin^*†‡§, Fu Zhenfu^*†‡§, Jiang Haitao^*,**††, Jiang Yangming^‡‡, Wang Fangzheng^*†‡§

Oncology Research, Vol.28, No.6, pp. 605-613, 2020, DOI:10.3727/096504020X16022401878096

Abstract The aim of this study was to explore the predictive role of pretreatment MRI-based radiomics on early response of neoadjuvant chemotherapy (NAC) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients. Between January 2016 and December 2016, a total of 108 newly diagnosed NPC patients who were hospitalized in the Cancer Hospital of the University of Chinese Academy of Sciences were reviewed. All patients had complete data of enhanced MR of nasopharynx before treatment, and then received two to three cycles of TP-based NAC. After 2 cycles of NAC, enhanced MR of nasopharynx was conducted again. Compared with the enhanced MR images… More >

IGOR A. KHLUSOV^1,*, LARISA S. LITVINOVA^2,*, KRISTINA A. YUROVA², MARINA Y. KHLUSOVA³

BIOCELL, Vol.46, No.6, pp. 1365-1373, 2022, DOI:10.32604/biocell.2022.018917

Abstract Stem cell microterritories (niches), as a specialized part of the extracellular matrix (ECM), are considered an important target and tool for the development of new materials, medical implants, and devices. However, tissue bioengineering products that have stem cell niches of known size on the surface or in the bulk structure of artificial materials are practically unknown. This brief review attempts to draw attention to the problematic aspects of niches as specific parts of the ECM, such as their hierarchy and size for mesenchymal stromal/stem cells (MSCs). These parameters arise directly from numerous definitions of stem cell niches as specialized morphological… More >

Laurence Desjardins^*

Oncologie, Vol.22, No.4, pp. 189-194, 2020, DOI:10.32604/oncologie.2020.012377

Abstract We describe the most frequent malignant intraocular tumors, conjunctival tumors and some lids and orbital tumors. Primary intraocular malignant tumors are retinoblastoma in children and uveal melanoma in adults. For uveal melanoma, the liver is the most frequent site of metastasis and this is why it is justified to prescribe liver ultrasonography every 6 months to these patients. Metastatic tumors can occur in the uvea and more frequently in the posterior part called the choroid. They are more frequent after breast cancer and lung cancer. Conjunctival tumors can be epithelial (benign papillomas and epidermoid carcinomas) or melanocytic (benign naevi and… More >

Ylenia Bartolacelli^*, Giulia Bragantini

Congenital Heart Disease, Vol.15, No.2, pp. 59-68, 2020, DOI:10.32604/CHD.2020.011448

Abstract Objective: The objective of this study was to assess left ventricle (LV) function and remodeling by three-dimensional echocardiography (3DE) in patients who underwent arterial switch procedure (ASO) for transposition of great arteries (TGA) in long-term follow-up. Methods and Results: We studied 54 asymptomatic patients (39 male) who have undergone single-stage ASO for TGA, aged 13.7 ± 4.7 years, with a normal LV ejection fraction (EF), compared to healthy peers. We evaluated LV volume and function in asymptomatic patients with normal ejection fraction by 3DE. All patients had normal EF, measured by modified Simpson’s method (mean 60.9 ± 3.5%) and by… More >