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  • Open Access

    ARTICLE

    The Association between Fear of COVID-19, Obsession with COVID-19, and Post Traumatic Stress Disorder in Korean Emergency Rescue Firefighters: A Cross-Sectional Study

    Yun-Jung Choi1, Heewon Song2,*

    International Journal of Mental Health Promotion, Vol.26, No.6, pp. 475-480, 2024, DOI:10.32604/ijmhp.2024.050824

    Abstract During the rapid spread of COVID-19, first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people. This uncertainty can have adverse mental health effects, such as increased anxiety and fear. This study aimed to investigate the degree of association between fear of COVID-19, obsession with COVID-19, and post-traumatic stress disorder (PTSD) in emergency rescue firefighters. The participants were 150 emergency rescue firefighters working in Region S, Korea. They filled out self-report questionnaires: The data obtained through the Fear of… More >

  • Open Access

    REVIEW

    The Effects of Mindfulness-Based Interventions on Symptoms of Mild Traumatic Brain Injury: A Systematic Review

    Qiqi Feng1, Zhijian Huang2, Yanqiu Wang1, Bin Wang1,*

    International Journal of Mental Health Promotion, Vol.26, No.6, pp. 417-428, 2024, DOI:10.32604/ijmhp.2024.049010

    Abstract Mindfulness-based interventions (MBIs) are emerging non-pharmacological treatments for mild traumatic brain injury (mTBI). In this systematic review, the authors aimed to evaluate the potential efficacy of MBIs to provide recommendations for treating patients with mTBI. We searched of the English literature on MBIs for patients with mTBI as of 01 September, 2023, using the PubMed, Web of Science, PsycINFO, and Scopus databases. One author performed data extraction and quality scoring of the included literature according to the proposed protocol, and another conducted the review. The review was not registered. A total of 11 studies met… More >

  • Open Access

    REVIEW

    Crossroads: Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

    YANG LI1,2, JIAN LIU1,3,*, YUEDI HU1,2, CHENGZHI CONG1,2, YIMING CHEN1,2, QIAO ZHOU1,2

    BIOCELL, Vol.48, No.1, pp. 9-19, 2024, DOI:10.32604/biocell.2023.045862

    Abstract Rheumatoid arthritis (RA) is a prevalent autoimmune disease whose main features include chronic synovial inflammation, bone destruction, and joint degeneration. Neutrophils are often considered to be the first responders to inflammation and are a key presence in the inflammatory milieu of RA. Neutrophil extracellular traps (NETs), a meshwork of DNA-histone complexes and proteins released by activated neutrophils, are widely involved in the pathophysiology of autoimmune diseases, especially RA, in addition to playing a key role in the neutrophil innate immune response. NETs have been found to be an important source of citrullinated autoantigen antibodies and More > Graphic Abstract

    Crossroads: Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

  • Open Access

    ARTICLE

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

    PING YANG1,2,3, YUANXIANG LAN1,2, ZHONG ZENG1,2, YAN WANG1,2, HECHUN XIA1,2,*

    BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367

    Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9… More > Graphic Abstract

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

  • Open Access

    ARTICLE

    Serial Multiple Mediation of the Relationship between Positive Coping Style and Post-Traumatic Growth among Chinese College Students in the Aftermath of COVID-19

    Qi Li, Jinsheng Hu*, Peng Wan

    International Journal of Mental Health Promotion, Vol.25, No.11, pp. 1173-1186, 2023, DOI:10.32604/ijmhp.2023.030343

    Abstract

    Given the ongoing character of COVID-19, higher-education students encountered multifaceted pressures brought about by the pandemic and had to overcome many difficulties during this period. Accordingly, it is imperative to identify the factors that may have protective effects on the social functioning and mental status of college students in the aftermath of COVID-19. This cross-sectional study sought to ascertain the internal mechanism of positive coping (PC) styles affecting post-traumatic growth (PTG) and considered the mediating roles of cognitive reappraisal (CR), psychological resilience (PR), and deliberate rumination (DR), which are essential for understanding how and to

    More >

  • Open Access

    ARTICLE

    Effectiveness of Post-Traumatic Growth Intervention to Promote Positive PostTraumatic Traits in Chinese Breast Cancer Patients: A Randomized Controlled Trial

    Cuirong Xu1,*, Han Yan2, Dawei Xu3, Guanjie Chen5, Qian Xu2, Kunpeng Li6, Yehao Rui7, Zanmin Song3, Neeraj Gill3, Jing Sun3,4,*

    International Journal of Mental Health Promotion, Vol.25, No.10, pp. 1089-1102, 2023, DOI:10.32604/ijmhp.2023.030526

    Abstract Objective: The purpose of this study was to evaluate the effectiveness of post-traumatic growth (PTG) model-based intervention to improve positive psychological traits in Chinese breast cancer patients. Design: A randomized control trial of a psychological group intervention based on PTG model. Methods: The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264. A total of 92 patients with breast cancer were recruited. The participants were randomly assigned to the experimental group (n = 46) and the control group (n = 46). A six-session psychological group intervention based on PTG model… More >

  • Open Access

    ARTICLE

    Coping with Trauma: The Relationship between Religiosity, Spirituality, and Post-Traumatic Symptoms among Civilians Exposed to Ongoing Rocket-Fire

    Jonathan T. Wolkinson, Michael Weinberg*

    International Journal of Mental Health Promotion, Vol.25, No.10, pp. 1137-1145, 2023, DOI:10.32604/ijmhp.2023.029641

    Abstract Living under ongoing shelling and missile attacks could cause a widespread of disruption of everyday life and emotional distress. Coping with such distress could be associated with the personal resources of religion and spirituality. The present study aimed to examine the relationships between religiosity and spirituality with Post Traumatic stress Disorder (PTSD) symptoms among a civilian population frequently exposed to missile and rocket threats. One hundred and twenty-four (N = 124) civilian participants living within 10 km from shelling and missile attacks fired towards them, completed demographic, religiosity, spirituality, and PTSD questionnaires. The study findings demonstrate… More >

  • Open Access

    ARTICLE

    Consultations de suivi à long terme d’adultes guéris d’un cancer survenu dans l’enfance : vécus traumatiques et travail de narration. Récits dans l’après-coup de la maladie

    M. Laget, L. Fasse, B. Fresneau, E. Ricadat, S. Rivollet

    Psycho-Oncologie, Vol.16, No.2, pp. 267-272, 2022, DOI:10.3166/pson-2022-0190

    Abstract Dans le cadre du dispositif de suivi médical destiné aux adultes guéris d’un cancer pédiatrique à l’Institut Gustave-Roussy (Villejuif, France), un entretien psychologique est proposé. Cet article s’appuie sur 198 entretiens auprès de patients ayant entre 18 et 67 ans, diagnostiqués entre 0 et 24 ans. Ces rencontres donnent à entendre la subjectivité du vécu du cancer et de la guérison, révélant les traces de cette expérience dans l’après-coup. Les enjeux de l’activité narrative amorcée dans le cadre de cette consultation, et pouvant se poursuivre au-delà, sont abordés dans une perspective métapsychologique. More >

  • Open Access

    ARTICLE

    Scutellarin alleviates complete freund’s adjuvant-induced rheumatoid arthritis in mice by regulating the Keap1/Nrf2/HO-1 pathway

    JIAN LI1, QINGQING WANG2, XIAOYING ZHANG1,*

    BIOCELL, Vol.47, No.6, pp. 1307-1316, 2023, DOI:10.32604/biocell.2023.028714

    Abstract Scutellarin (SCU) is a herbal flavonoid glucuronide with multiple pharmacological activities, including anti-oxidant, anti-inflammation, vascular relaxation, anti-platelet, and myocardial protection. However, the effect of SCU on complete Freund’s adjuvant (CFA)-induced rheumatoid arthritis (RA) had not been studied. In this study, we investigated the beneficial effects of SCU in the CFA-induced RA mice model and the anti-arthritic activity was evaluated by paw edema. Enzyme-linked immunosorbent assay (ELISA) was carried out to evaluate the plasma levels of immunoglobulin (Ig)G, IgE, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, receptor activator of nuclear factor-κB ligand (RANKL), and osteoprotegerin (OPG).… More >

  • Open Access

    ARTICLE

    Reciprocal Association between Psychological Distress and PTSD and Their Relationship with Pre-Displacement Stressors among Displaced Women

    Erhabor S. Idemudia1, Babatola D. Olawa1,*, Gail E. Wyatt2, Norweeta G. Milburn2

    International Journal of Mental Health Promotion, Vol.25, No.5, pp. 699-710, 2023, DOI:10.32604/ijmhp.2023.026852

    Abstract It is established in the psychological literature that pre-displacement stressors, PTSD symptoms, and psychological distress are associated among internally displaced persons. However, existing studies have not demonstrated the mechanism underlying these associations. This study compared two explanatory models; one with PTSD symptoms severity explaining the indirect association between pre-displacement stressors and psychological distress, and the other with psychological distress explaining the indirect relationship between pre-displacement stressors and PTSD symptoms severity. In a cross-sectional design, 631 women (Mean age = 31.18 ± 8.59) were conveniently and purposely selected from the displaced women harboured in two camps… More >

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