Xinyang Liu*1, Zhichao Wang†1, Guoliang Zhang‡1, Qikun Zhu‡, Hui Zeng‡, Tao Wang‡, Feng Gao‡, Zhan Qi‡, Jinwen Zhang§, Rui Wang‡
Oncology Research, Vol.25, No.4, pp. 485-493, 2017, DOI:10.3727/096504016X14749340314441
Abstract Esophageal cancer is one of the most common types of cancer, and it has a poor prognosis. The molecular
mechanisms of esophageal cancer progression remain largely unknown. In this study, we aimed to investigate
the clinical significance and biological function of tumor necrosis factor receptor-associated factor 6 (TRAF6)
in esophageal cancer. Expression of TRAF6 in esophageal cancer was examined, and its correlation with clinicopathological factors and patient prognosis was analyzed. A series of functional and mechanism assays were
performed to further investigate the function and underlying mechanisms in esophageal cancer. Expression
of TRAF6 was highly… More >
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