Mehmet Sitki Copur*†, Julie Marie Wurdeman†, Debra Nelson*, Ryan Ramaekers*, Dron Gauchan*, David Crockett*
Oncology Research, Vol.26, No.3, pp. 515-518, 2018, DOI:10.3727/096504017X15128550060375
Abstract Solid tumors involving glandular organs express mucin glycoprotein that is eventually shed into the circulation. As a
result, these proteins can easily be measured in the serum and be used as potential tumor markers. The most commonly used tumor markers for breast cancer are CA27-29 and CA15-3, which both measure the glycoprotein
product of the mucin-1 (MUC1) gene. CA27-29 has been approved by the US Food and Drug Administration
for monitoring disease activity in breast cancer patients. Most oncology clinical practice guidelines do not
recommend the use of tumor markers for routine surveillance of early… More >
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