Chengyan Luo, Jiangnan Qiu
Oncology Research, Vol.25, No.8, pp. 1341-1348, 2017, DOI:10.3727/096504017X14867268787969
Abstract Cervical cancer is among the most common cancers inflicting women worldwide. Understanding the pathological mechanisms of cervical cancer development is critical for identifying novel targets for cervical cancer
treatment. MicroRNAs (miRs) have various roles in regulating cancer development. In this study, we investigated the potential role of miR-181a and its target in regulating cervical cancer development and chemotherapy
resistance. The expression of miR-181a was evaluated and modulated in several human cervical cancer cell
lines. The role of miR-181a in regulating cervical cancer growth and chemotherapy sensitivity was investigated
in cell culture models and mouse tumor… More >
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