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  • Open Access

    PROCEEDINGS

    Study on the Flow Dead Zone in the Shell of an Industrial Tubular Fixed Bed Reactor

    Binbin Hao1, Zhenming Liu1,*, Yajun Deng1,*, Dongliang Sun1, Wei Zhang1, Bo Yu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012194

    Abstract The tubular fixed bed reactor is widely used in industrial production because of its strong applicability, high stability and easy maintenance. The flow dead zone in the shell of the reactor will significantly affect the overall performance of the reactor. Reducing the flow dead zone in the shell is the main way to optimize the performance of tubular fixed bed reactor. At present, most of the research on the flow dead zone of the reactor is based on the simplified reactor model, the number and size of tubes are far from the industrial requirements. In… More >

  • Open Access

    ARTICLE

    Tubular Heat Enhancement Using Twisted Tape Inserts with Large Holes

    Ali Jaber Abdulhamed*, Aws Al-Akam, Wisam J. Khudhayer, Ali Sabri Allw

    Energy Engineering, Vol.121, No.2, pp. 273-290, 2024, DOI:10.32604/ee.2023.045583 - 25 January 2024

    Abstract Heat augmentation techniques play a vital role in the heating and cooling processes in industries, including solar collectors and many applications that utilize heat exchangers. Several studies are based on inserting fillers inside the tubes to enhance heat transfer. This investigation considered the effects of twisted tapes with large holes on a tubular heat exchanger’s (HX) heat transmission, pressure drop, and thermal boosting factor. In the experimental section, counter-swirl flow generators used twisted tapes with pairs of 1.0 cm-diameter holes and changes in porosity (Rp) at 1.30% and 2.70%. In the experiments, air was utilized as… More >

  • Open Access

    ARTICLE

    Experimental Study on the Thermal Performances of a Tube-Type Indirect Evaporative Cooler

    Tiezhu Sun*, Huan Sun, Tingzheng Tang, Yongcheng Yan, Peixuan Li

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.10, pp. 2519-2531, 2023, DOI:10.32604/fdmp.2023.027118 - 25 June 2023

    Abstract The so-called indirect evaporative cooling technology is widely used in air conditioning applications. The thermal characterization of tube-type indirect evaporative coolers, however, still presents challenges which need to be addressed to make this technology more reliable and easy to implement. This experimental study deals with the performances of a tube-type indirect evaporative cooler based on an aluminum tube with a 10 mm diameter. In particular, the required tests were carried out considering a range of dry-bulb temperatures between 16°C and 18°C and a temperature difference between the wet-bulb and dry-bulb temperature of 2°C∼4°C. The integrated convective More > Graphic Abstract

    Experimental Study on the Thermal Performances of a Tube-Type Indirect Evaporative Cooler

  • Open Access

    ARTICLE

    Improved Design of a Hydraulically Expanded Overhead Cylinder for an Automotive Torsion Beam

    Kefan Yang1,*, Youmin Wang1, Kexun Fu1, Jiaqi Chen2

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.5, pp. 1317-1338, 2023, DOI:10.32604/fdmp.2023.024265 - 30 November 2022

    Abstract The design of hydro-bulge molds, able to provide hollow parts with special-shaped cross-sections, is still a pretty complicated task (especially for what concerns the design of the related hydraulic system and its “synchronization”). In the present work, this task is addressed through the introduction of a new type of overhead cylinder hydraulic synchronization system, able to correct automatically any deviation from the optimal process. Using the AMESim software, the displacement synchronization curve of the piston rods of the two cylinders is obtained and it is verified that the system is able to implement an automatic More >

  • Open Access

    ARTICLE

    Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both

    CLAIRE ELIZABETH HILLS, ELEFTHERIOS SIAMANTOURAS, PAUL EDWARD SQUIRES*

    BIOCELL, Vol.46, No.4, pp. 937-940, 2022, DOI:10.32604/biocell.2022.018414 - 15 December 2021

    Abstract Changes in cell-cell and cell-substrate adhesion markers are increasingly used to characterize disease onset and progression. However, these relationships depend on both the biochemical and molecular association between cells and between cells and their extracellular matrix, as well as the biophysical and mechanical properties orchestrated by cytoskeletal, membrane and matrix components. To fully appreciate the role of cell adhesion when determining normal physiology and the impact of disease on cellular function, it is important to consider both biochemical and biophysical attributes of the system being investigated. In this short viewpoint we reflect on our experiences More >

  • Open Access

    ARTICLE

    HSA-MIR-203/MyD88 axis mediates the protective effect of hispidulin on LPS-induced apoptosis in a human renal tubular epithelial line, HK-2

    SICONG WANG1, RUIJIN LIU2, QIUYUAN HAN2, KAIJIANG YU3,*

    BIOCELL, Vol.46, No.1, pp. 149-158, 2022, DOI:10.32604/biocell.2021.013027 - 29 September 2021

    Abstract Acute kidney injury (AKI), commonly occurring as complications of sepsis, cardiac surgery, and liver or kidney transplantation, is a critical care syndrome. It is well known that lipopolysaccharide (LPS) shock is a common triggering factor for AKI. This study is aimed to examine the effect of flavonoid compound hispidulin on LPS-induced AKI. For this, renal tubular epithelial cell HK-2 was treated with LPS to establish an in vitro model of AKI. The effect of hispidulin on HK-2 cell viability was examined using CCK-8 assay. Cell apoptosis was determined by TUNEL and flow cytometry. Apoptosis marker proteins… More >

  • Open Access

    ARTICLE

    Baseline tubular biomarkers in young adults with congenital heart disease as compared to healthy young adults: Detecting subclinical kidney injury

    Dana Y. Fuhrman1,2, Lan Nguyen3, Morgan Hindes3, John A. Kellum2

    Congenital Heart Disease, Vol.14, No.6, pp. 963-967, 2019, DOI:10.1111/chd.12862

    Abstract Background: There are significant implications for kidney disease in young adults with congenital heart disease. Prior investigations have not focused on the use of urinary tubular biomarkers for the early identification of kidney disease in this growing patient group.
    Objective: Determine if young adults with congenital heart disease have differences in the baseline concentration of urinary tubular biomarkers when compared to healthy young adults.
    Design/Methods: In a pilot case control study, 30 patients from 18 to 35 years of age with congenital heart disease and a normal serum creatinine were recruited during a routine follow-up visit. In the… More >

  • Open Access

    ABSTRACT

    Differential Organization of Airway Smooth Muscle Cells on Tubular Surface as A Novel Mechanobiology Mechanism of Airway Tissue Morphogenesis

    Linhong Deng1,*, Yang Jin2, Mingzhi Luo1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 80-80, 2019, DOI:10.32604/mcb.2019.07370

    Abstract Airway smooth muscle cells (ASMCs) exists within the bronchial airway wall in a form of spirally winding bundles [1]. This pattern emerges early during embryonic development and is involved in airway branching [2], providing the airway appropriate contractile capacity and resistance to circumferential tension in health or causing excessive airway narrowing in disease such as asthma. Despite its importance, the cause of ASMCs self-organization remains largely a mystery. Previously, we have demonstrated in 2D that ASMCs can sense the curvature in their microenvironment and change behaviors in differentiation, orientation and migration accordingly [3]. Here we… More >

  • Open Access

    ARTICLE

    CFD INVESTIGATIONS OF THERMAL AND DYNAMIC BEHAVIORS IN A TUBULAR HEAT EXCHANGER WITH BUTTERFLY BAFFLES

    AlemKarimaa,*, Sahel Djamelb , Nemdili Alic, Ameur Houarid

    Frontiers in Heat and Mass Transfer, Vol.10, pp. 1-7, 2018, DOI:10.5098/hmt.10.27

    Abstract In the present paper, the effects of a new baffle design on the efficiency of a tubular heat exchanger are numerically investigated. It concerns butterfly baffles inserted in a cylindrical tube heat exchanger. We focus on the influence of the shape of baffles, the space between baffles (pitch ratio, PR) and the baffle size (i.e. the blockage ratio, BR) on the heat transfer and flow characteristics. Three geometrical configurations with different PRs are realized (PR = 1, 2 and 4) and five others with different blockage ratios (BR = 0.1, 0.2, 0.3, 0.4 and 0.5). More >

  • Open Access

    ARTICLE

    Microtubular Protofilament Analysis Based on Molecular Level Tubulin Interaction

    JongWon Kim1,2, Ning Li2, Ramana Pidaparti2,*, Xianqiao Wang2,*

    Molecular & Cellular Biomechanics, Vol.15, No.3, pp. 127-141, 2018, DOI:10.3970/mcb.2018.02669

    Abstract Nonlinear microstructure of the microtubules (MTs) plays an important role in their mechanical properties. Despite the extensive efforts into the development of continuum models for microtubules, a mesoscale finite element model that can link the molecular level information to the overall performance of microtubules is still missing. The aim of this study is to develop a molecular dynamics model (MDM), finite element model (FEM) and structural mechanics beam model (SMBM) for tubulins of protofilament (PF). In MDM, the backbone atoms of α-tubulin were fixed while the backbone atoms of β-tubulin were attached to a molecular… More >

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