Ping Zhao*, Hai-Tao Guan†, Zhi-Jun Dai†, Yu-Guang Ma†, Xiao-Xu Liu†, Xi-Jing Wang†
Oncology Research, Vol.25, No.1, pp. 115-122, 2017, DOI:10.3727/096504016X14732772150181
Abstract Tripartite motif-containing protein 37 (TRIM37), a new member of the RING-B-box-coiled-coil (RBCC) subfamily of zinc finger proteins, was found to be involved in the development and progression of several cancers.
However, the expression pattern and biological functions of TRIM37 in colorectal cancer (CRC) remain unknown.
Therefore, in the present study, we examined the expression pattern of TRIM37 in CRC and investigated the
function of TRIM37 in the progression of CRC. Our results showed that TRIM37 expression was upregulated in
CRC cell lines. Knockdown of TRIM37 inhibited CRC cell proliferation and tumor growth in vivo. Furthermore, More >
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