Xiaowei Shen*1, Jianping Huang†1, Gang Liu†, Hao Zhang†, Xiwei Zhang†, Xiancheng Kong†, Lei Du†
Oncology Research, Vol.26, No.7, pp. 1133-1142, 2018, DOI:10.3727/096504018X15168461629558
Abstract Neuroblastoma is a major contributor of cancer-specific mortality. Although remarkable enhancement has been
achieved in the treatment of neuroblastoma in patients with early stage disease, limited progress has been made
in the treatment of patients with high-risk neuroblastoma. Thus, innovative approaches are required to achieve
further improvements in neuroblastoma patient survival outcomes. The major alkaloid obtained from Sophora
flavescens Ait, matrine, has been shown to counteract malignancy in various kinds of cancers. In the current
study, we evaluated the effects of matrine on the migration and proliferation of neuroblastoma cells. Cell cycle
analysis coupled with Transwell More >
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