Rabindranath Bera^1,#, Yotaro Ochi^2,3, Ying-Jung Huang¹, Ming-Chung Kuo^1,4, Kenichi Yoshida⁵, Seishi Ogawa², Lee-Yung Shih^1,4,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070259 - 30 December 2025

Abstract Background: Breakpoint Cluster Region-Abelson (BCR::ABL1) fusion protein is essential in the pathogenesis of chronic myeloid leukemia (CML); however, the chronic-to-blast phase transformation remains elusive. We identified novel kinesin light chain 2 (KLC2) mutations in CML-myeloid blast phase patients. We aimed to examine the functional role of KLC2 mutations in leukemogenesis. Methods: To evaluate the biological role of KLC2 mutants (MT) in CML cells, we expressed KLC2-MT in different human CML cell lines harboring BCR::ABL1 and performed immunoblot, immunofluorescence, cell proliferation, differentiation, and apoptosis; Tyrosine kinase inhibitor (TKI)-drug activities; and clonogenic assays for in vitro functional analyses. We co-expressed KLC2-MT… More >

Illia Khurtin^*, Mukesh Prasad

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-15, 2026, DOI:10.32604/cmc.2025.067481 - 09 December 2025

Abstract The field of artificial intelligence has advanced significantly in recent years, but achieving a human-like or Artificial General Intelligence (AGI) remains a theoretical challenge. One hypothesis suggests that a key issue is the formalisation of extracting meaning from information. Meaning emerges through a three-stage interpretative process, where the spectrum of possible interpretations is collapsed into a singular outcome by a particular context. However, this approach currently lacks practical grounding. In this research, we developed a model based on contexts, which applies interpretation principles to the visual information to address this gap. The field of computer… More >

Yungui Guo^*, Xuan Fan

Journal of Psychology in Africa, Vol.35, No.6, pp. 791-796, 2025, DOI:10.32604/jpa.2025.067238 - 30 December 2025

Abstract This study examined the moderating role of employees’ learning orientation on the relationship between leaders’ artificial intelligence symbolization behavior (LAISB), employees’ attitude towards digital transformation (ATDT), and enterprise digital transformation. The sample consisted of 261 employees from five enterprises in China (female = 34.5%; primary industry includes the internet and transportation; mean age = 42.51 years, SD = 8.63 years; bachelor’s degree or above = 72.8%). The results of structural equation modeling and simple slope test indicated that LAISB predicted higher enterprise digital transformation, with ATDT partial mediation. Furthermore, employees’ learning orientation weakened the relationship More >

Saurabh Singh^1,2, Sudip Pandey^3,*, Ankush Kumar Jain¹

Revue Internationale de Géomatique, Vol.34, pp. 899-914, 2025, DOI:10.32604/rig.2025.071156 - 09 December 2025

Abstract Urban expansion in semi-arid regions poses critical challenges for sustainable land management, ecological resilience, and heritage conservation. Jaipur, India—a United Nations Educational, Scientific and Cultural Organization (UNESCO) World Heritage City located in a semi-arid environment—faces rapid urbanization that threatens agricultural productivity, fragile ecosystems, and cultural assets. This study quantifies past and projects future land use/land cover (LULC) dynamics in Jaipur to support evidence-based planning. Using the Dynamic World dataset, we generated annual 10-m LULC maps from 2016 to 2025 within the municipal boundary. Temporal change detection was conducted through empirical transition probability analysis, and future… More >

Muflih Alhazmi¹, Waqar Ul Hassan², Saba Shaheen³, Mohammed M. A. Almazah⁴, Azmat Ullah Khan Niazi^3,*, Nafisa A. Albasheir⁵, Ameni Gargouri⁶, Naveed Iqbal⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1903-1940, 2025, DOI:10.32604/cmes.2025.072973 - 26 November 2025

Abstract This paper proposes a model-based control framework for vehicle platooning systems with second-order nonlinear dynamics operating over switching signed networks, time-varying delays, and deception attacks. The study includes two configurations: a leaderless structure using Finite-Time Non-Singular Terminal Bipartite Consensus (FNTBC) and Fixed-Time Bipartite Consensus (FXTBC), and a leader—follower structure ensuring structural balance and robustness against deceptive signals. In the leaderless model, a bipartite controller based on impulsive control theory, gauge transformation, and Markovian switching Lyapunov functions ensures mean-square stability and coordination under deception attacks and communication delays. The FNTBC achieves finite-time convergence depending on initial More >

Ihsan Qadir¹, Usama Naeem², Ahmed Nouman³, Aamir Raza⁴, Jun Wu^1,*

Revue Internationale de Géomatique, Vol.34, pp. 831-853, 2025, DOI:10.32604/rig.2025.069020 - 10 November 2025

Abstract The Jhelum River Basin in Pakistan has experienced recurrent and severe flooding over the past several decades, leading to substantial economic losses, infrastructure damage, and socio-environmental disruptions. This study uses multi-temporal satellite remote sensing data with historical hydrological records to map the spatial and temporal dynamics of major flood events occurring between 1988 and 2019. By utilizing satellite imagery from Landsat 5, Landsat 8, and Sentinel-2, key flood events were analyzed through the application of water indices such as the Normalized Difference Water Index (NDWI) and the Modified NDWI (MNDWI) to delineate flood extents. Historical… More >

Sophia Strukel¹, Vikrant Rai^1,2,*

BIOCELL, Vol.49, No.10, pp. 1887-1911, 2025, DOI:10.32604/biocell.2025.067207 - 22 October 2025

Abstract Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus and are associated with high morbidity, risk of amputation, and increased mortality. Although DFUs typically remain a chronic, non-healing wound, a small portion of DFUs may undergo malignant transformation. The subsequent malignancies are skin cancers such as squamous cell carcinoma (SCC), basal cell carcinoma, or melanoma. Understanding the pathophysiology of DFUs and the molecular and clinical determinants that contribute to their potential malignant transformation if crucial for clinical management. Chronic inflammation, dysregulation of cytokine signaling, faulty immune surveillance, and impaired wound healing all play… More >

Chao Li^1,3,#, Chen Wang^1,3,#, Caichang Ding^2,*, Yonghao Liao^1,3, Zhiwei Ye^1,3

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3129-3149, 2025, DOI:10.32604/cmc.2025.067440 - 23 September 2025

Abstract Deep learning-based semantic communication has achieved remarkable progress with CNNs and Transformers. However, CNNs exhibit constrained performance in high-resolution image transmission, while Transformers incur high computational cost due to quadratic complexity. Recently, VMamba, a novel state space model with linear complexity and exceptional long-range dependency modeling capabilities, has shown great potential in computer vision tasks. Inspired by this, we propose MNTSCC, an efficient VMamba-based nonlinear joint source-channel coding (JSCC) model for wireless image transmission. Specifically, MNTSCC comprises a VMamba-based nonlinear transform module, an MCAM entropy model, and a JSCC module. In the encoding stage, the… More >

Zhiying Sun¹, Guolong Zhao^2,3, Feng Hu^1,*

Journal of Psychology in Africa, Vol.35, No.4, pp. 513-521, 2025, DOI:10.32604/jpa.2025.070126 - 17 August 2025

Abstract This study examined the relationship between transformational leadership and employee bootleg innovation through the mediating role of creative self-efficacy and the moderating role of leader-member exchange (LMX). Data were collected from 279 employees and 56 matched supervisors within a large Chinese digital transformation group. A moderated mediation model analysis found that transformational leadership predicts higher employee bootleg innovation. Creative self-efficacy mediated the positive relationship between transformational leadership and employee bootleg. Additionally, leader-member exchange significantly moderated the relationship between transformational leadership and creative self-efficacy, for a further enhancement of bootleg innovation. These findings underscore the importance More >

Mingchen Gao^*

Energy Engineering, Vol.122, No.8, pp. 3243-3263, 2025, DOI:10.32604/ee.2025.065957 - 24 July 2025

Abstract Currently, the international economic situation is becoming increasingly complex, and there is significant downward pressure on the global economy. In recent years, China’s infrastructure sector has experienced rapid growth, with the structure of its power engineering business gradually shifting from traditional infrastructure construction to more diversified areas such as production and operation, as well as emergency repairs. As a result, the transformation of mechanized construction in power transmission and transformation projects has become increasingly urgent. This article proposes a post-evaluation model based on game theory to improve comprehensive weighting and fuzzy grey relational projection sorting,… More > Graphic Abstract