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  • Open Access

    ARTICLE

    Hybrid Multi-Infeed Interaction Factor Calculation Method Considering Voltage Regulation Control Characteristics of Voltage Source Converter

    Shan Liu1, Chengbin Chi1, Fengze Han2, Yanan Wu1, Lin Zhu1, Tuo Wang2,*

    Energy Engineering, Vol.121, No.8, pp. 2257-2273, 2024, DOI:10.32604/ee.2024.049861

    Abstract Voltage source converter based high voltage direct current (VSC-HVDC) can participate in voltage regulation by flexible control to help maintain the voltage stability of the power grid. In order to quantitatively evaluate its influence on the voltage interaction between VSC-HVDC and line commutated converter based high voltage direct current (LCC-HVDC), this paper proposes a hybrid multi-infeed interaction factor (HMIIF) calculation method considering the voltage regulation control characteristics of VSC-HVDC. Firstly, for a hybrid multi-infeed high voltage direct current system, an additional equivalent operating admittance matrix is constructed to characterize HVDC equipment characteristics under small disturbance.… More >

  • Open Access

    RETRACTION

    Retraction: Liquiritigenin Inhibits Colorectal Cancer Proliferation, Invasion, and Epithelial-to-Mesenchymal Transition by Decreasing Expression of Runt-Related Transcription Factor 2

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.8, pp. 1373-1373, 2024, DOI:10.32604/or.2024.055031

    Abstract This article has no abstract. More >

  • Open Access

    CORRECTION

    Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

    HUI SUN, MASANORI KAWANO*, TATSUYA IWASAKI, ICHIRO ITONAGA, YUTA KUBOTA, HIROSHI TSUMURA, KAZUHIRO TANAKA

    Oncology Research, Vol.32, No.8, pp. 1369-1370, 2024, DOI:10.32604/or.2024.052652

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Hypoxia-inducible factor 1alpha and vascular endothelial growth factor in Glioblastoma Multiforme: a systematic review going beyond pathologic implications

    DIMITRA P. VAGELI1,2,*, PANAGIOTIS G. DOUKAS3, KERASIA GOUPOU2, ANTONIOS D. BENOS2, KYRIAKI ASTARA2,4, KONSTANTINA ZACHAROULI2, SOTIRIS SOTIRIOU5, MARIA IOANNOU2

    Oncology Research, Vol.32, No.8, pp. 1239-1256, 2024, DOI:10.32604/or.2024.052130

    Abstract Glioblastoma multiforme (GBM) is an aggressive primary brain tumor characterized by extensive heterogeneity and vascular proliferation. Hypoxic conditions in the tissue microenvironment are considered a pivotal player leading tumor progression. Specifically, hypoxia is known to activate inducible factors, such as hypoxia-inducible factor 1alpha (HIF-1α), which in turn can stimulate tumor neo-angiogenesis through activation of various downward mediators, such as the vascular endothelial growth factor (VEGF). Here, we aimed to explore the role of HIF-1α/VEGF immunophenotypes alone and in combination with other prognostic markers or clinical and image analysis data, as potential biomarkers of GBM prognosis… More >

  • Open Access

    REVIEW

    Aldo-keto reductases: Role in cancer development and theranostics

    SIDDAVARAM NAGINI1, PRATHAP REDDY KALLAMADI2, KRANTHI KIRAN KISHORE TANAGALA3, GEEREDDY BHANUPRAKASH REDDY2,*

    Oncology Research, Vol.32, No.8, pp. 1287-1308, 2024, DOI:10.32604/or.2024.049918

    Abstract Aldo-keto reductases (AKRs) are a superfamily of enzymes that play crucial roles in various cellular processes, including the metabolism of xenobiotics, steroids, and carbohydrates. A growing body of evidence has unveiled the involvement of AKRs in the development and progression of various cancers. AKRs are aberrantly expressed in a wide range of malignant tumors. Dysregulated expression of AKRs enables the acquisition of hallmark traits of cancer by activating oncogenic signaling pathways and contributing to chemoresistance. AKRs have emerged as promising oncotherapeutic targets given their pivotal role in cancer development and progression. Inhibition of aldose reductase… More >

  • Open Access

    REVIEW

    Biological characteristics and clinical management of uveal and conjunctival melanoma

    SNJEŽANA KAŠTELAN1,2, ANA DIDOVIĆ PAVIČIĆ3, DARIA PAŠALIĆ4, TAMARA NIKUŠEVA-MARTIĆ5, SAMIR ČANOVIĆ3,7, PETRA KOVAČEVIĆ1,6,*, SUZANA KONJEVODA3,7

    Oncology Research, Vol.32, No.8, pp. 1265-1285, 2024, DOI:10.32604/or.2024.048437

    Abstract Uveal and conjunctival melanomas are relatively rare tumors; nonetheless, they pose a significant risk of mortality for a large number of affected individuals. The pathogenesis of melanoma at different sites is very similar, however, the prognosis for patients with ocular melanoma remains unfavourable, primarily due to its distinctive genetic profile and tumor microenvironment. Regardless of considerable advances in understanding the genetic characteristics and biological behaviour, the treatment of uveal and conjunctival melanoma remains a formidable challenge. To enhance the prospect of success, collaborative efforts involving medical professionals and researchers in the fields of ocular biology… More > Graphic Abstract

    Biological characteristics and clinical management of uveal and conjunctival melanoma

  • Open Access

    ARTICLE

    Chaotic Elephant Herd Optimization with Machine Learning for Arabic Hate Speech Detection

    Badriyya B. Al-onazi1, Jaber S. Alzahrani2, Najm Alotaibi3, Hussain Alshahrani4, Mohamed Ahmed Elfaki4, Radwa Marzouk5, Heba Mohsen6, Abdelwahed Motwakel7,*

    Intelligent Automation & Soft Computing, Vol.39, No.3, pp. 567-583, 2024, DOI:10.32604/iasc.2023.033835

    Abstract In recent years, the usage of social networking sites has considerably increased in the Arab world. It has empowered individuals to express their opinions, especially in politics. Furthermore, various organizations that operate in the Arab countries have embraced social media in their day-to-day business activities at different scales. This is attributed to business owners’ understanding of social media’s importance for business development. However, the Arabic morphology is too complicated to understand due to the availability of nearly 10,000 roots and more than 900 patterns that act as the basis for verbs and nouns. Hate speech… More >

  • Open Access

    ARTICLE

    Drive Train Cooling Options for Electric Vehicles

    Randeep Singh1,*, Tomoki Oridate2, Tien Nguyen2

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 703-717, 2024, DOI:10.32604/fhmt.2024.050744

    Abstract Electrification of vehicles intensifies their cooling demands due to the requirements of maintaining electronics/electrical systems below their maximum temperature threshold. In this paper, passive cooling approaches based on heat pipes have been considered for the thermal management of electric vehicle (EV) traction systems including battery, inverter, and motor. For the battery, a heat pipe base plate is used to provide high heat removal (180 W per module) and better thermal uniformity (<5°C) for the battery modules in a pack while downsizing the liquid cold plate system. In the case of Inverter, two phase cooling system… More > Graphic Abstract

    Drive Train Cooling Options for Electric Vehicles

  • Open Access

    ARTICLE

    Analysis of Convective Heat Exchanges and Fluid Dynamics in the Air Gap of a Discoid Technology Rotary Machine

    Abdellatif El Hannaoui1,*, Rachid Boutarfa1, Chadia Haidar2

    Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 733-746, 2024, DOI:10.32604/fhmt.2024.050520

    Abstract The proposed work focuses on the in-depth study of convective heat transfer in the unconfined air gap of a discoidal rotor-stator system. The rotary cooling mechanism is achieved by the injection of two air jets, while the cavity geometry is characterized by a dimensionless parameter G. The numerical analysis primarily concentrated on the effect of flow velocity and rotation on the heat exchange process. More precisely, the range of analysis extends from the rotational Reynolds number to , while varying the Reynolds value of the jet in a range from to . To carry out More >

  • Open Access

    ARTICLE

    An Integrated Bipolar Picture Fuzzy Decision Driven System to Scrutinize Food Waste Treatment Technology through Assorted Factor Analysis

    Navaneethakrishnan Suganthi Keerthana Devi1, Samayan Narayanamoorthy1, Thirumalai Nallasivan Parthasarathy1, Chakkarapani Sumathi Thilagasree2, Dragan Pamucar3,4,*, Vladimir Simic5,6, Hasan Dinçer7,8, Serhat Yüksel7,8

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2665-2687, 2024, DOI:10.32604/cmes.2024.050954

    Abstract Food Waste (FW) is a pressing environmental concern that affects every country globally. About one-third of the food that is produced ends up as waste, contributing to the carbon footprint. Hence, the FW must be properly treated to reduce environmental pollution. This study evaluates a few available Food Waste Treatment (FWT) technologies, such as anaerobic digestion, composting, landfill, and incineration, which are widely used. A Bipolar Picture Fuzzy Set (BPFS) is proposed to deal with the ambiguity and uncertainty that arise when converting a real-world problem to a mathematical model. A novel Criteria Importance Through… More >

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