DAN GUO¹, XI XIA^2,*, JIAN YANG^1,*

BIOCELL, Vol.48, No.7, pp. 1023-1036, 2024, DOI:10.32604/biocell.2024.051095

Abstract Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine. In recent years, the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements. This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure. Here, we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure. Furthermore, we explored the challenges in transitioning More >

Ruijin Huo^1,2,3, Qingxiang Pei^1,2,3, Xiaohui Yuan^1,*, Yanming Xu³

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 2053-2077, 2024, DOI:10.32604/cmes.2024.049185

Abstract In this paper, a generalized th-order perturbation method based on the isogeometric boundary element method is proposed for the uncertainty analysis of broadband structural acoustic scattering problems. The Burton-Miller method is employed to solve the problem of non-unique solutions that may be encountered in the external acoustic field, and the th-order discretization formulation of the boundary integral equation is derived. In addition, the computation of loop subdivision surfaces and the subdivision rules are introduced. In order to confirm the effectiveness of the algorithm, the computed results are contrasted and analyzed with the results under Monte More >

Xu Xu¹, Xiaoteng Wang¹, Haitian Yang¹, Zhenjun Yang², Yiqian He^1,3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1831-1861, 2024, DOI:10.32604/cmes.2024.048199

Abstract The multiscale method provides an effective approach for the numerical analysis of heterogeneous viscoelastic materials by reducing the degree of freedoms (DOFs). A basic framework of the Multiscale Scaled Boundary Finite Element Method (MsSBFEM) was presented in our previous works, but those works only addressed two-dimensional problems. In order to solve more realistic problems, a three-dimensional MsSBFEM is further developed in this article. In the proposed method, the octree SBFEM is used to deal with the three-dimensional calculation for numerical base functions to bridge small and large scales, the three-dimensional image-based analysis can be conveniently… More >

Suping Shen^1,2, Baris Burak Kanbur^1,2, Chenlong Wu², Fei Duan^1,2,*

Frontiers in Heat and Mass Transfer, Vol.22, No.2, pp. 397-415, 2024, DOI:10.32604/fhmt.2024.048984

Abstract The design of three-dimensional printing based conformal cooling channels (CCCs) in injection molding holds great significance. Compared to CCCs, conformal cooling (CC) cavity solutions show promise in delivering enhanced cooling performance for plastic products, although they have been underexplored. In this research, CC cavity is designed within the mold geometry, reinforced by body-centered cubic (BCC) lattice structures to enhance mechanical strength. Three distinct BCC lattice variations have been integrated into the CC cavity: the BCC structure, BCC with cubes, and BCC with pillars. The thermal performances of the BCC lattice-added CC cavity are assessed numerically… More > Graphic Abstract

Xingliang Deng¹, Peng Cao^2,*, Yintao Zhang¹, Yuhui Zhou³, Xiao Luo¹, Liang Wang³

Energy Engineering, Vol.121, No.5, pp. 1195-1207, 2024, DOI:10.32604/ee.2023.045870

Abstract The fractured-vuggy carbonate oil resources in the western basin of China are extremely rich. The connectivity of carbonate reservoirs is complex, and there is still a lack of clear understanding of the development and topological structure of the pore space in fractured-vuggy reservoirs. Thus, effective prediction of fractured-vuggy reservoirs is difficult. In view of this, this work employs adaptive point cloud technology to reproduce the shape and capture the characteristics of a fractured-vuggy reservoir. To identify the complex connectivity among pores, fractures, and vugs, a simplified one-dimensional connectivity model is established by using the meshless More >

Arunn Narasimhan^*, Kaushal Kumar Jha

Frontiers in Heat and Mass Transfer, Vol.2, No.3, pp. 1-8, 2011, DOI:10.5098/hmt.v2.3.3005

Abstract Pan Retinal photocoagulation (PRP), a retinal laser surgical process, is simulated using a three-dimensional bio-heat transfer numerical model. Spots of two different type of array, square array of 3 × 3 spots and a circular array of six spots surrounding a central spot, are sequentially irradiated. Pennes bio-heat transfer model is used as the governing equation. Finite volume method is applied to find the temperature distribution due to laser irradiation inside the human eye. Each spot is heated for 100 ms and subsequently cooled for 100 ms with an initial laser power of 0.2 W. More >

Georg F. Dietze^†, Reinhold Kneer

Frontiers in Heat and Mass Transfer, Vol.2, No.3, pp. 1-14, 2011, DOI:10.5098/hmt.v2.3.3001

Abstract Despite the use of liquid films in a wide variety of technical applications involving heat and mass transfer (e.g. nuclear reactors, cooling towers and gas turbines), where they often play an important role, the underlying momentum and heat transport processes within these thin liquid layers remain to be fully elucidated. In particular, this applies to the influence that surface waves, developing due to the film’s natural instability, exert on the mentioned processes. In this context, it has been suggested by several experimental and numerical observations that momentum and heat transfer in the capillary wave region… More >

Long Chen¹, Yan Yu¹, Yanpeng Shang¹, Zhonghou Wang^1,*, Jing Zhang²

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 817-846, 2024, DOI:10.32604/cmes.2023.031595

Abstract Gears are pivotal in mechanical drives, and gear contact analysis is a typically difficult problem to solve. Emerging isogeometric analysis (IGA) methods have developed new ideas to solve this problem. In this paper, a three-dimensional body parametric gear model of IGA is established, and a theoretical formula is derived to realize single-tooth contact analysis. Results were benchmarked against those obtained from commercial software utilizing the finite element analysis (FEA) method to validate the accuracy of our approach. Our findings indicate that the IGA-based contact algorithm successfully met the Hertz contact test. When juxtaposed with the More > Graphic Abstract

Lioua Kolsi^a,b,*

Frontiers in Heat and Mass Transfer, Vol.7, pp. 1-10, 2016, DOI:10.5098/hmt.7.26

Abstract In this study, the effects of Richardson and Hartmann numbers on heat and mass transfer in a three-dimensional lid-driven cubical cavity subjected to a uniform magnetic field are investigated numerically. The lid is maintained at constant high temperature and is moving downwards in the negative y-direction. The wall opposite to the lid is stationary and maintained at constant low temperature, and all other walls are kept adiabatic. Entropy generation is also calculated to investigate the nature of irreversibility in heat transfer inside the cavity. The computations are performed for the Richardson numbers 10 and 100, More >

Vitaliy Suvorov^1,2,*, Olga Loboda², Maria Balakina¹, Igor Kulczycki²

Congenital Heart Disease, Vol.18, No.5, pp. 491-505, 2023, DOI:10.32604/chd.2023.030583

Abstract Background: Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment outcomes. The introduction of this technique into pediatric cardiac surgery will allow us to study features of the anatomy and spatial relations of a defect and to simulate the optimal surgical repair on a printed model in every individual case. Methods: We performed the prospective cohort study which included 29 children with congenital heart defects. The hearts and the great vessels were modeled and printed out. Measurements of the same cardiac areas were taken in the… More > Graphic Abstract