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  • Open Access

    ARTICLE

    Experimental Study on the Bubble Dynamics of Magnetized Water Boiling

    Yang Cao1,*, Jianshu Liu2, Xuhui Meng1

    Frontiers in Heat and Mass Transfer, Vol.22, No.2, pp. 675-685, 2024, DOI:10.32604/fhmt.2024.051208

    Abstract Boiling heat transfer, as an efficient heat transfer approach, that can absorb a large amount of latent heat during the vaporization, is especially suitable for heat transfer occasions with high heat flux demands. Experimental studies show that the surface tension coefficient of pure water can be reduced sharply (up to 25%) when it is magnetized by a magnetic field applied externally. In this paper, magnetized water (MW) was used as the work fluid to conduct boiling heat transfer experiments, to explore the influence of magnetization on the boiling characteristics of pure water. The electromagnetic device… More >

  • Open Access

    REVIEW

    Treatment and Clinical Management of Chronic Thromboembolic Pulmonary Hypertension: An Update of Literature Review

    Yuan Ren1, Yingxian Sun1, Zhiguang Yang2, Yanli Chen1,*

    Congenital Heart Disease, Vol.19, No.2, pp. 157-176, 2024, DOI:10.32604/chd.2024.047930

    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for More >

  • Open Access

    ARTICLE

    Finite Element Simulations of the Localized Failure and Fracture Propagation in Cohesive Materials with Friction

    Chengbao Hu1,2,3, Shilin Gong4,*, Bin Chen1,2,3, Zhongling Zong4, Xingwang Bao5, Xiaojian Ru5

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 997-1015, 2024, DOI:10.32604/cmes.2024.048640

    Abstract Strain localization frequently occurs in cohesive materials with friction (e.g., composites, soils, rocks) and is widely recognized as a fundamental cause of progressive structural failure. Nonetheless, achieving high-fidelity simulation for this issue, particularly concerning strong discontinuities and tension-compression-shear behaviors within localized zones, remains significantly constrained. In response, this study introduces an integrated algorithm within the finite element framework, merging a coupled cohesive zone model (CZM) with the nonlinear augmented finite element method (N-AFEM). The coupled CZM comprehensively describes tension-compression and compression-shear failure behaviors in cohesive, frictional materials, while the N-AFEM allows nonlinear coupled intra-element discontinuities More >

  • Open Access

    ARTICLE

    Research on Anti-Fluctuation Control of Winding Tension System Based on Feedforward Compensation

    Yujie Duan1, Jianguo Liang1,*, Jianglin Liu1, Haifeng Gao1, Yinhui Li2, Jinzhu Zhang1, Xinyu Wen3

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1239-1261, 2024, DOI:10.32604/cmes.2023.044400

    Abstract In the fiber winding process, strong disturbance, uncertainty, strong coupling, and fiber friction complicate the winding constant tension control. In order to effectively reduce the influence of these problems on the tension output, this paper proposed a tension fluctuation rejection strategy based on feedforward compensation. In addition to the bias harmonic curve of the unknown state, the tension fluctuation also contains the influence of bounded noise. A tension fluctuation observer (TFO) is designed to cancel the uncertain periodic signal, in which the frequency generator is used to estimate the critical parameter information. Then, the fluctuation More >

  • Open Access

    CASE REPORT

    Pulmonary Hypertension Crisis in Patient with Tetralogy of Fallot and Mixed Total Anomalous Pulmonary Vein Connection after the Primary Correction: A Rare Case Report

    Dian Kesumarini1,2, Yunita Widyastuti3, Cindy Elfira Boom1, Lucia Kris Dinarti4,*

    Congenital Heart Disease, Vol.18, No.6, pp. 671-678, 2023, DOI:10.32604/chd.2023.044746

    Abstract Tetralogy of Fallot (TOF) with total anomalous pulmonary vein connections (TAPVC) is a rare type of complex congenital heart disease among all TOF cases. Co-presentation of major aortopulmonary collateral arteries (MAPCAs) compensates for the lack of central pulmonary blood flow and decreases the severity of right-to-left shunting in TOF. We present a case of a 2-year-old child with complex diagnoses of TOF, TAPVC, a large secundum atrial septal defect (ASD), and intraoperatively identified MAPCAs. She underwent surgery to repair the TAPVC, valve-sparing reconstruction of the right ventricular outflow tract, interventricular defect closure, and the creation… More >

  • Open Access

    ARTICLE

    Wellbore Cleaning Degree and Hydraulic Extension in Shale Oil Horizontal Wells

    Xin Ai1,2,*, Mian Chen1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.3, pp. 661-670, 2024, DOI:10.32604/fdmp.2023.026819

    Abstract

    The efficient development and exploitation of shale oil depends on long-distance horizontal wells. As the degree of cleaning of the wellbore plays a key role in these processes, in this study, this problem is investigated experimentally by focusing on the dimensionless cuttings bed height. A method is proposed to calculate the horizontal-well hydraulic extension taking into account the influence of the wellbore cleaning degree on the wellbore pressure distribution and assess the effect of a variety of factors such as the bottom hole pressure, the circulating pressure drop, the drilling pump performance and the formation

    More >

  • Open Access

    ARTICLE

    Dynamics along the epithelial-cancer biointerface: Hidden system complexities

    IVANA PAJIC-LIJAKOVIC*, MILAN MILIVOJEVIC

    BIOCELL, Vol.47, No.11, pp. 2321-2334, 2023, DOI:10.32604/biocell.2023.043796

    Abstract The biointerface dynamics influence any cancer spreading through the epithelium since it is documented in the early stages some malignancies (like epithelial cancer). The altered rearrangement of epithelial cells has an impact on the development of cancer. Therefore, it is necessary to comprehend the underlying biological and physical mechanisms of this biointerface dynamics for early suppression of cancer. While the biological mechanisms include cell signaling and gene expression, the physical mechanisms are several physical parameters such as the epithelial-cancer interfacial tension, epithelial surface tension, and compressive stress accumulated within the epithelium. Although the segregation of… More > Graphic Abstract

    Dynamics along the epithelial-cancer biointerface: Hidden system complexities

  • Open Access

    ARTICLE

    NR4A1 enhances glycolysis in hypoxia-exposed pulmonary artery smooth muscle cells by upregulating HIF-1α expression

    CHENYANG CHEN1,*, JUAN WEN1, WEI HUANG1, JIANG LI2,*

    BIOCELL, Vol.47, No.11, pp. 2423-2433, 2023, DOI:10.32604/biocell.2023.044459

    Abstract Background: Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that is strongly associated with dysregulation of glucose metabolism. Alterations in nuclear receptor subfamily 4 group A member 1 (NR4A1) activity alter the outcome of PAH. This study aimed to investigate the effects of NR4A1 on glycolysis in PAH and its underlying mechanisms. Methods: This study included twenty healthy volunteers and twenty-three PAH patients, and plasma samples were collected from the participants. To mimic the conditions of PAH in vitro, a hypoxia-induced model of pulmonary artery smooth muscle cell (PASMC) model was established. The proliferation… More > Graphic Abstract

    NR4A1 enhances glycolysis in hypoxia-exposed pulmonary artery smooth muscle cells by upregulating HIF-1α expression

  • Open Access

    PROCEEDINGS

    A Data-Fusion Method for Uncertainty Quantification of Mechanical Property of Bi-Modulus Materials: An Example of Graphite

    Liang Zhang1,*, Zigang He1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.09713

    Abstract The different elastic properties of tension and compression are obvious in many engineering materials, especially new materials. Materials with this characteristic, such as graphite, ceramics, and composite materials, are called bi-modulus materials. Their mechanical properties such as Young’s modulus have randomness in tension and compression due to different porosity, microstructure, etc. To calibrate the mechanical properties of bi-modulus materials by bridging FEM simulation results and scarce experimental data, the paper presents a data-fusion computational method. The FEM simulation is implemented based on Parametric Variational Principle (PVP), while the experimental result is obtained by Digital Image… More >

  • Open Access

    PROCEEDINGS

    Extension of Ordinary State-Based Peridynamic Model for Nonlinear Analysis

    Mengnan Zhang1,*, Fucheng Tian1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09593

    Abstract Peridynamic is a nonlocal theory that uses integral forms of governing equations, making it suitable for describing objects with discontinuous states such as cracks. After more than two decades of development, peridynamic has been effectively applied to numerous solid mechanics studies. However, in the field of ordinary state-based peridynamic modeling nonlinear deformation, a more comprehensive model that can establish a general connection with continuum mechanics and allow for the selection of different influence functions is still lacking. As a consequence, a further extension to existing models is promising, and it represents a substantial addition to… More >

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