Eric Bourreau¹, Gérard Fleury², Philippe Lacomme^2,*

Journal of Quantum Computing, Vol.6, pp. 25-51, 2024, DOI:10.32604/jqc.2024.048792 - 25 October 2024

Abstract The paper presents a novel quantum method for addressing two fundamental routing problems: the Traveling Salesman Problem (TSP) and the Vehicle Routing Problem (VRP), both central to routing challenges. The proposed method, named the Indirect Quantum Approximate Optimization Algorithm (IQAOA), leverages an indirect solution representation using ranking. Our contribution focuses on two main areas: 1) the indirect representation of solutions, and 2) the integration of this representation into an extended version of QAOA, called IQAOA. This approach offers an alternative to QAOA and includes the following components: 1) a quantum parameterized circuit designed to simulate… More >

HEYI LIU^1,#, WENHAO CHENG^2,#, JINGLIANG HE², LUYAO ZHANG², KADIRYA ASAN², YULU CHEN², JIAYUN WANG², QI GAO², SENG WANG², ZIEN YU², SHAOJIE MA², LAN ZHU^3,*, JING JI^2,3,*

BIOCELL, Vol.48, No.10, pp. 1465-1473, 2024, DOI:10.32604/biocell.2024.052670 - 02 October 2024

Abstract Background: Osteosarcoma is the most common primary bone malignancy, with a strong tendency towards local invasion and metastasis. The SRY-Box Transcription Factor 1 (SOX1) gene, a member of the HMG-box family of DNA-binding transcription factors, plays a crucial role in embryogenesis and tumorigenesis. However, its role in osteosarcoma, particularly in relation to metastatic potential, is not well understood. Methods: The GSE14359 dataset containing five samples of conventional osteosarcoma and four samples of lung metastatic osteosarcoma was obtained from the Gene Expression Omnibus (GEO) database and analyzed for differential gene expression using the R language. Gene… More >

Rodrigo Vidonscky Pinto¹, Flávio Augusto Sanzovo Fiorelli^2,*

Frontiers in Heat and Mass Transfer, Vol.21, pp. 427-443, 2023, DOI:10.32604/fhmt.2023.041917 - 30 November 2023

Abstract The present work provides an experimental and numerical procedure to obtain the geometrical position of the hotspots of a microprocessor using the thermal images obtained from the transient thermal response of this processor subject to pulsating stress tests. This is performed by the solution of the steady inverse heat transfer problem using these thermal images, resulting in qualitative heat source distributions; these are analyzed using the mean heat source gradients to identify the elements that can be considered hotspots. This procedure identified that the processor INTEL Core 2 Quad Q8400S contains one hotspot located in More >

Adel A. Rezk^1,2,*, Hala A. Amin²

Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 691-705, 2023, DOI:10.32604/phyton.2022.024208 - 29 November 2022

Abstract Citrus Tristeza Virus (CTV), usually occurs in nature as a mixture of genotypes. Six naturally infected citrus (Citrus sinensis) trees grafted on sour orange rootstock were collected from three citrus growing governorates in Egypt (Sharqia, Qalyubia and Garbia). In this study, RT-PCR, Single-Strand Conformation Polymorphism (SSCP) and nucleotide sequence analysis were used for four independent CTV genomic regions (p65, p18, p20, and p23) to detect and assess the sequence and genetic variabilities among CTV Egyptian isolates. RTPCR products (650 bp) for the CTV p23 gene obtained from the selected isolates were used for the SSCP analysis… More >

Chuan Wang^1,*, Ruoyu Zhu², Yi Jiang³, Weili Liu⁴, Sang-Woon Jeon⁵, Lin Sun², Hua Wang⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.2, pp. 1209-1228, 2023, DOI:10.32604/cmes.2022.022807 - 27 October 2022

Abstract The dynamic traveling salesman problem (DTSP) is significant in logistics distribution in real-world applications in smart cities, but it is uncertain and difficult to solve. This paper proposes a scheme library-based ant colony optimization (ACO) with a two-optimization (2-opt) strategy to solve the DTSP efficiently. The work is novel and contributes to three aspects: problem model, optimization framework, and algorithm design. Firstly, in the problem model, traditional DTSP models often consider the change of travel distance between two nodes over time, while this paper focuses on a special DTSP model in that the node locations… More >

J. Priya^*, C. Palanisamy

Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 243-259, 2023, DOI:10.32604/iasc.2023.025719 - 06 June 2022

Abstract The Internet of Things (IoT) and Cloud computing are gaining popularity due to their numerous advantages, including the efficient utilization of internet and computing resources. In recent years, many more IoT applications have been extensively used. For instance, Healthcare applications execute computations utilizing the user’s private data stored on cloud servers. However, the main obstacles faced by the extensive acceptance and usage of these emerging technologies are security and privacy. Moreover, many healthcare data management system applications have emerged, offering solutions for distinct circumstances. But still, the existing system has issues with specific security issues,… More >

Baraket Nada^1,2,3,*, Brandelet Benoit¹, Trouvé Gwenaëlle², Rogaume Yann¹

FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.5, pp. 1419-1425, 2022, DOI:10.32604/fdmp.2022.021753 - 27 May 2022

Abstract One option to fight global warming is to convert our use of fossil energy into renewables such as biomass energy. However, the forest preservation and the quality of the ambient air are also two major issues. Therefore, the use of biomass waste without any supplementary emissions could represent a part of the solution. In this study, two fuels were considered for a 200 kW moving grate boiler. A multicyclone and a bag filter were fitted on the boiler. The first fuel consisted of classical wood chips whereas the second was a mixture of wood chips… More >

Juan Guo¹, Yanzhu Liu^2,*, Shan Li³, Zhi Li⁴, Sonia Kherbachi⁵

CMC-Computers, Materials & Continua, Vol.68, No.2, pp. 2145-2157, 2021, DOI:10.32604/cmc.2021.016411 - 13 April 2021

Abstract With the rapid development of mobile communication technology, the application of internet of vehicles (IoV) services, such as for information services, driving safety, and traffic efficiency, is growing constantly. For businesses with low transmission delay, high data processing capacity and large storage capacity, by deploying edge computing in the IoV, data processing, encryption and decision-making can be completed at the local end, thus providing real-time and highly reliable communication capability. The roadside unit (RSU), as an important part of edge computing in the IoV, fulfils an important data forwarding function and provides an interactive communication… More >

Yue Kui Jian¹, Huan Ye Zhu¹, Xing Lin Wu, Bo Li

Oncology Research, Vol.27, No.2, pp. 211-218, 2019, DOI:10.3727/096504018X15208993118389

Abstract Osteosarcomas, especially those with metastatic or unresectable disease, have limited treatment options. The antitumor effects of pharmacologic inhibitors of angiogenesis in osteosarcomas are hampered in patients by the rapid development of tumor resistance, notably through increased invasiveness and accelerated metastasis. Here we demonstrated that thrombospondin 1 (TSP-1) is a potent inhibitor of the growth and metastasis of the osteosarcoma cell line MG-63. Moreover, we demonstrate that upregulation of TSP-1 facilitated expression of vasculostatin in MG-63 cells. In angiogenesis assays, overexpression of TSP-1 inhibited MG-63 cells and induced tube formation of human umbilical vein endothelial cells More >