DILIXIATI JINSIHAN, DAN LI, MINGSHUAI ZHANG, JINCHUN FENG, QIAN ZHAO*
BIOCELL, Vol.45, No.3, pp. 671-684, 2021, DOI:10.32604/biocell.2021.012519
- 03 March 2021
Abstract Hypoxia affects the advancement, metastasis, and metabolism of breast cancer (BC). The circular RNA
ribonuclease P RNA component H1 (circRPPH1) (has_circ_0000515) is implicated in tumor progression.
Nevertheless, the regulatory mechanism related to circRPPH1 in hypoxia-mediated triple-negative breast cancer
(TNBC) progression is indistinct. The expression levels of circRPPH1, miR-1296-5p, tripartite motif-containing 14
(TRIM14) mRNA in tissue samples and cells were examined through quantitative real-time polymerase chain reaction
(qRT-PCR). Cell viability, migration, and invasion were determined with Cell Counting Kit-8 (CCK-8) or transwell
assays. The levels of glucose consumption and lactate production were assessed via the Glucose… More >
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