JI SHI1,2, YE ZHANG2, YI CHEN2, TANGJUN GUO3,*, HAOZHE PIAO2,*
BIOCELL, Vol.48, No.8, pp. 1241-1263, 2024, DOI:10.32604/biocell.2024.051049
Abstract Background: Glioblastoma multiforme (GBM) is the most general malignancy of the primary central nervous system that is characterized by high aggressiveness and lethality. Transmembrane protein 159 (TMEM159) is an endoplasmic reticulum protein that can form oligomers with seipin. The TMEM159-seipin complex decides the site of lipid droplet (LD) formation, and the formation of LDs is a marker of GBM. However, the role of TMEM159 in the progression of GBM has not been investigated to date. Methods: In this study, we examined the genes that may be associated with patient prognosis in GBM by bioinformatics analyses,… More >
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