XUFU QIN1,#, ZIYE JIANG1,#, YONGCUI ZHU1,*, HONGPENG XUE1, CHENGQUN WEI2
Oncology Research, Vol.29, No.4, pp. 263-273, 2021, DOI:10.32604/or.2022.03568
- 31 August 2022
Abstract The abnormal expression of long noncoding RNAs (lncRNAs) is frequently observed in gastric cancer (GC) and considered an important driving force in GC progression. However, little is known regarding the involvement of TMEM147-AS1 in GC. Therefore, we examined TMEM147-AS1 expression in GC and determined its prognostic value. In addition, TMEM147-AS1 expression was depleted to identify the functional changes in response to TMEM147-AS1 deficiency. Using the cancer genome atlas dataset and our own cohort, we identified a strong expression of TMEM147-AS1 in GC. Increased TMEM147-AS1 levels in GC showed a significant association with poor prognosis. TMEM147-AS1… More >
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