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  • Open Access

    PROCEEDINGS

    Towards High-Fidelity and Efficient Computation for Diagnosis and Treatment of Cardiovascular Disease

    Lei Wang1,*, Blanca Rodriguez2, Xiaoyu Luo3, Charles Augarde4

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.013350

    Abstract Cardiovascular disease is the leading cause of death worldwide. Disease-specific software, like FFRct from HeartFlow, and high-fidelity computational models within a general-purpose software, like Living Heart Project within Abaqus, are essential to revolutionise diagnosis and treatment of cardiovascular disease for clinicians and design of medical devices for industries. This talk presents our past researches on computational modelling of tear propagation in the aortic dissection [1-2] and of electromechanical coupling in the human heart with the finite element method [3], and our current exploration on high-fidelity and efficient computation and software development for diagnosis and treatment More >

  • Open Access

    PROCEEDINGS

    Three-Dimensionally Printed Transition Metal Catalysts with Hierarchically Porous Structures for Wastewater Purification

    Sheng Guo1,2,*, Mengmeng Yang1, Yao Huang2, Xizi Gao1, Chao Cai3,*, Kun Zhou4,5,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012655

    Abstract 3D printing technology has demonstrated considerable potential in wastewater remediation. Zero-valent metal (ZVM) has been recognized as an efficient catalyst facilitating the organic pollutant degradation in water. However, owing to its inclination toward oxidation and aggregation, the practical utilization of ZVM remains a challenge. Herein, we have employed 3D printing techniques to fabricate hierarchically porous ZVM, such as zero-valent copper and zero-valent iron, which exhibit a high level of printing precision and commendable resistance to compression. These 3D-ZVM catalysts can effectively activate peroxymonosulfate (PMS), thereby degrading various organic pollutants, including tetracycline, ciprofloxacin, rhodamine B, and… More >

  • Open Access

    PROCEEDINGS

    Fatigue Behaviors of Thick Cruciform Joints Made by Q355D Structural Steel Under Different Post-Welding Treatments

    Wei Song1,*, Xiaojian Shi2, Shoupan Wei2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.012236

    Abstract Different post-welding treatments, such as TIG-Dressing, blinding, HFMI et.al are often used for steel welded joints in construction machinery manufacturing as an effective and reliable method for fatigue strength improvement. This paper investigates the fatigue performance of thick Q355D cruciform joints in heavy load-carrying steel structures under different treatments. Two TIG-Dressing treatments, blinding and HFMI for the full-penetration welded joints were used for fatigue tests. Experimental tests studied the fatigue strength of cruciform welded joints of Q355D structural steel under different treatments. The geometric parameters and relevant statistical analyses were performed by actual 3D optical More >

  • Open Access

    PROCEEDINGS

    Treatments of Fractures Intersection in the Enriched-Embedded Discrete Fracture Model (nEDFM) for Porous Flow

    Kaituo Jiao1, Dongxu Han2,*, Bo Yu2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-3, 2024, DOI:10.32604/icces.2024.011520

    Abstract Motivated by the fractures being very thin compared to the size of rock matrix, utilizing the non-conforming grid is an efficient approach to simulate fluid flow in fractured porous media. The embedded discrete fracture model (EDFM) is the typical one that using the conforming grid and modelled based on the finite volume method (FVM) framework. The EDFM maintains advantages of mass conservation and low computational complexity, but it cannot characterize blocking fractures and has a low accuracy on the mass exchange between fractures and matrix [1]. In our previous work [2], we developed the enriched-EDFM… More >

  • Open Access

    ARTICLE

    Mechanical Behavior of Panels Reinforced with Orthogonal Plant Fabrics: Experimental and Numerical Assessment

    Martha L. Sánchez1,*, G. Capote2

    Journal of Renewable Materials, Vol.12, No.10, pp. 1791-1810, 2024, DOI:10.32604/jrm.2024.055122 - 23 October 2024

    Abstract The construction sector is one of the main sources of pollution, due to high energy consumption and the toxic substances generated during the processing and use of traditional materials. The production of cement, steel, and other conventional materials impacts both ecosystems and human health, increasing the demand for ecological and biodegradable alternatives. In this paper, we analyze the properties of panels made from a combination of plant fibers and castor oil resin, analyzing the viability of their use as construction material. For the research, orthogonal fabrics made with waste plant fibers supplied by a company… More >

  • Open Access

    ARTICLE

    Assessment of Operational Performance in a Power Generation/Selling Integrated Company Using a Dynamic Proportional Adjustment Coefficient

    Jingbin Wu1,*, Hongming Yang2, Sheng Xiang2

    Energy Engineering, Vol.121, No.11, pp. 3263-3287, 2024, DOI:10.32604/ee.2024.054019 - 21 October 2024

    Abstract Currently, the operational performance assessment system in the power market primarily focuses on power generation and electricity retail companies, lacking a system tailored to the operational characteristics of power generation/selling integrated companies. Therefore, this article proposes an assessment index system for assessing the operational performance of a power generation/selling integrated company, encompassing three dimensions: basic capacity, development potential, and external environment. A dynamic proportional adjustment coefficient is designed, along with a subjective and objective weighting model for assessment indexes based on a combined weighting method. Subsequently, the operational performance of an integrated company is assessed More > Graphic Abstract

    Assessment of Operational Performance in a Power Generation/Selling Integrated Company Using a Dynamic Proportional Adjustment Coefficient

  • Open Access

    COMMENTARY

    Redefining the tumor microenvironment with emerging therapeutic strategies

    SULING XU1, XIAO LI2, WENXUE MA3,*

    Oncology Research, Vol.32, No.11, pp. 1701-1708, 2024, DOI:10.32604/or.2024.055161 - 16 October 2024

    Abstract The environment surrounding a tumor, known as the tumor microenvironment (TME), plays a role in how cancer progresses and responds to treatment. It poses both challenges and opportunities for improving cancer therapy. Recent progress in understanding the TME complexity and diversity has led to approaches for treating cancer. This perspective discusses the strategies for targeting the TME, such as adjusting networks using extracellular vesicles to deliver drugs and enhancing immune checkpoint inhibitors (ICIS) through combined treatments. Furthermore, it highlights adoptive cell transfer (ACT) therapies as an option for tumors. By studying how components of the More >

  • Open Access

    ARTICLE

    Piperlongumine in combination with EGFR tyrosine kinase inhibitors for the treatment of lung cancer cells

    SHAIL RAKESH MODI, TERRICK ANDEY*

    Oncology Research, Vol.32, No.11, pp. 1709-1721, 2024, DOI:10.32604/or.2024.053972 - 16 October 2024

    Abstract Objectives: EGFR tyrosine kinase inhibitor (EGFR-TKI) therapies such as erlotinib and gefitinib are approved for the treatment of non-small cell lung cancer (NSCLC). However, the high incidence of acquired resistance to these EGFR-TKIs may preclude their effectiveness. Piperlongumine (PPL), an extract from the long pepper fruit (Piper longum), has been shown to possess anticancer properties. The purpose of the study was to investigate piperlongumine as an anticancer agent and to study a combination treatment approach with EGFR-TKIs against lung cancer cells. Methods: Anticancer efficacy of PPL, erlotinib (ERL), gefitinib (GEF), and cisplatin (CIS) were investigated in… More >

  • Open Access

    ARTICLE

    Is ypTNM staging a comparable predictor as pTNM staging for survival in non-metastatic rectal cancer after preoperative chemoradiation therapy?

    JEN-PIN CHUANG1,2,3, HSIANG-LIN TSAI4,5, WEI-CHIH SU4,6,7, PO-JUNG CHEN4,6, CHING-WEN HUANG4,5, TSUNG-KUN CHANG4,6,7, YEN-CHENG CHEN4,6, CHING-CHUN LI4,8, YUNG-SUNG YEH4,9,10, TZU-CHIEH YIN4,5,11, JAW-YUAN WANG4,5,6,12,13,*

    Oncology Research, Vol.32, No.11, pp. 1723-1732, 2024, DOI:10.32604/or.2024.052098 - 16 October 2024

    Abstract Background: The pTNM staging system is widely recognized as the most effective prognostic indicator for cancer. The latest update of this staging system introduced a new pathological staging system (ypTNM) for patients receiving neoadjuvant chemoradiotherapy (NACRT). However, whether the prognostic value of the ypTNM staging system for rectal cancer is similar to that of the pTNM staging system remains unclear. This study was conducted to compare the ypTNM and pTNM staging systems in terms of their prognostic value for patients with nonmetastatic rectal cancer undergoing proctectomy. Material and Methods: This study was conducted at a large teaching… More >

  • Open Access

    PROCEEDINGS

    Simple but Effective Heat Treatment on Hot Isostatic Press Diffusion Bonded Ni60A Hardfacing Layer

    Lei Yu1,2, Yingjie Yan1,2, Hao Dong3,4, Suk-Chun Moon5,*, Zhengyi Jiang5,*, Rui Cao1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.011941

    Abstract Ni60A hardfacing alloy, as one of the highest-alloy grades and hardest alloy of Ni-Cr-B-Si alloys, is expected to be used as hardfacing alloy for thrust discs in nuclear main pumps to reduce friction, corrosion and erosion. Since mechanical properties of Ni-Cr-B-Si alloys are very sensitive to their defects and microstructures, heat treatment/remelting methods have been used to eliminate porosity and to modify microstructural heterogeneity. In our previous research, Ni60A hardfacing layer with high micro-hardness and excellent bonding strength has been fabricated onto 0Cr18Ni10Ti austenitic stainless steel using hot isostatic press diffusion bonding technique. However, some… More >

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