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  • Open Access

    ARTICLE

    Unveiling Ionic Conductivity and Ion Transport Properties in Polyvinyl Alcohol-Based Gel Polymer Electrolytes with Quaternary Ammonium Iodide

    M. F. Aziz1,2,*, A. A. Rahim1, A. R. M. Rais1,2,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1097-1109, 2025, DOI:10.32604/jpm.2025.071129 - 26 December 2025

    Abstract To study the behavior of structural dynamics, ionic conductivity and ion transport properties, the gel polymer electrolytes (GPEs) was developed using polyvinyl alcohol in combination with potassium iodide, dimethyl sulfoxide, ethylene carbonate, propylene carbonate and tetra-N-propylammonium iodide (C12H28IN), The GPEs were synthesized via a solution mixing technique, systematically varying the tetra-N-propylammonium iodide concentration to optimize ionic transport properties. The gel polymer electrolytes (GPEs) preparation was initially dissolving the potassium iodide and tetra-N-propylammonium iodide in a measured combination of ethylene carbonate, propylene carbonate, and dimethyl sulfoxide within a glass container. Subsequently, polyvinyl alcohol (PVA) was introduced into… More >

  • Open Access

    ARTICLE

    Deep Learning-Based Prediction of Seepage Flow in Soil-Like Porous Media

    Zhenzhen Shen1,2, Kang Yang2, Dengfeng Wei2, Quansheng Liang2, Zhenpeng Ma2, Hong Wang2, Keyu Wang2, Chunwei Zhang2, Xiaohu Yang3,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.11, pp. 2741-2760, 2025, DOI:10.32604/fdmp.2025.070395 - 01 December 2025

    Abstract The rapid prediction of seepage mass flow in soil is essential for understanding fluid transport in porous media. This study proposes a new method for fast prediction of soil seepage mass flow by combining mesoscopic modeling with deep learning. Porous media structures were generated using the Quartet Structure Generation Set (QSGS) method, and a mesoscopic-scale seepage calculation model was applied to compute flow rates. These results were then used to train a deep learning model for rapid prediction. The analysis shows that larger average pore diameters lead to higher internal flow velocities and mass flow More >

  • Open Access

    ARTICLE

    A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot

    Yang Xu1,#, Yaqi Zhang2,#, Meijiao Zhu3, Pengcheng Xue4, Siyu Ma1, Di Yu1, Liang Hu1, Yuxi Zhang1, Wei Peng1, Jirong Qi1, Xuyun Wen4, Ming Yang3, Xuming Mo1,2,5,*

    Congenital Heart Disease, Vol.20, No.5, pp. 559-570, 2025, DOI:10.32604/chd.2025.072242 - 30 November 2025

    Abstract Background: The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental trajectories, and cognition-related changes that unfold over time. Methods: We introduce an magnetic resonance imaging (MRI) dataset comprising TOF children who underwent brain MRI scanning and cross-sectional neurocognitive follow-up. The dataset includes brain three-dimensional T1-weighted imaging (3D-T1WI), three-dimensional T2-weighted imaging (3D-T2WI), and neurodevelopmental evaluations using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition (WPPSI-IV). Results: Thirty-one children with TOF (age range: 4–33 months; 18 males) were recruited and completed corrective surgery at the Children’s Hospital of Nanjing More >

  • Open Access

    PROCEEDINGS

    Dynamics and Control of a Tethered Solar Sail Spacecraft for Solar Corona Observation Under the Sun-Earth CRTBP Framework

    Xinyu Jiang1, Chongrui Du1, Yamin Wang2, Honghua Dai1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-1, 2025, DOI:10.32604/icces.2025.011552

    Abstract Persistent high-resolution observation of the solar corona is essential for advancing human’s understanding of critical solar phenomena, including coronal heating, solar wind acceleration, and the initiation of coronal mass ejections that significantly impact space weather. This study proposes a novel space-based solar corona observation mission concept, which uses a tethered solar sail spacecraft to create a sustained artificial total solar eclipse near the Sun-Earth L2 point. By positioning a probe at the end of Earth’s umbra cone and leveraging Earth as a natural occulter, the mission enables uninterrupted observations of the innermost solar corona. To… More >

  • Open Access

    PROCEEDINGS

    Electrochemical Pneumatic Battery for Compact, Efficient, and Silent Robotic Actuation

    Junyu Ge1, Yifan Wang1, Hong Li1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-3, 2025, DOI:10.32604/icces.2025.011446

    Abstract The advancement of untethered and adaptive robotic systems necessitates the development of compact, efficient, and silent pneumatic power sources [1,2]. Traditional pneumatic actuation relies on bulky compressors or external gas reservoirs, limiting their practical applications in mobile and autonomous systems [3,4]. This work presents a novel electrochemical pneumatic battery (EPB) that exploits electrochemical driven gas generation to achieve controlled and energy-efficient pneumatic actuation, offering a viable alternative to conventional air supply methods. The EPB operates through an electrochemical redox mechanism based on a zinc-oxygen battery [5–7], enabling reversible gas storage and controlled pressure modulation. This… More >

  • Open Access

    ARTICLE

    Tetramethylpyrazine Alleviates Pancreatitis Progression by Regulating Inflammation and Autophagy through the YAP-RIPK1-NF-κB Axis

    Hong Wu, Yang Liu*

    BIOCELL, Vol.49, No.10, pp. 1985-2006, 2025, DOI:10.32604/biocell.2025.069527 - 22 October 2025

    Abstract Background: Acute pancreatitis (AP) is a serious gastrointestinal disorder. Tetramethylpyrazine (TMP), a bioactive alkaloid extracted from Ligusticum chuanxiong, exhibits various pharmacological effects, but its protective mechanisms against AP remain unclear. This study aimed to investigate the protective effects and underlying mechanisms of TMP in AP. Methods: The study utilized Cerulein (CER) to model pancreatitis across experimental systems. Cellular responses were characterized through functional assays (CCK-8 viability, EdU proliferation, Transwell migration, flow cytometric apoptosis, Fluo-3/AM calcium imaging) and inflammatory profiling (ELISA for trypsin, CRP, TNF-α, IL-1β, IL-6). Autophagy was monitored via mRFP-GFP-LC3 flux and LysoTracker staining, with… More > Graphic Abstract

    Tetramethylpyrazine Alleviates Pancreatitis Progression by Regulating Inflammation and Autophagy through the YAP-RIPK1-NF-<b>κ</b>B Axis

  • Open Access

    ARTICLE

    UHMK1 Promotes Prostate Cancer Progression through a Positive Feedback Loop with MTHFD2

    Chi Zhang1,#, Xi Huang2,#, Cheng Hu1, Bowen Tang1, Jianjie Wu1, Zhuolun Sun1, Weian Zhu1, Xiangfu Zhou1, Hengjun Xiao1,*, Hua Wang1,*

    Oncology Research, Vol.33, No.9, pp. 2331-2351, 2025, DOI:10.32604/or.2025.065119 - 28 August 2025

    Abstract Background: U2AF homology motif kinase 1 (UHMK1) has been associated with RNA processing and protein phosphorylation, thereby influencing tumor progression. The study aimed to explore its regulatory mechanisms and biological functions in human prostate cancer (PCa). Methods: In this study, we systematically evaluated the expression and prognostic significance of UHMK1 in public databases, followed by validation through immunohistochemistry (IHC) in PCa specimens. Both gain-of-function and loss-of-function experiments were conducted to elucidate the role of UHMK1 in vitro and in vivo. Additionally, a series of molecular and biochemical assays were performed to investigate the regulatory mechanisms underlying UHMK1… More >

  • Open Access

    ARTICLE

    Preparation of N,S-Doped Biochar via Modulating Chitosan and Sodium Dodecyl Benzene Sulfonate Interaction and Its Adsorption Performance

    Jun-Jie Yang1, Ran An1, Jing-Heng Nie1, Hao-Miao Ma1, Yu-Qing Yan1, Yuan-Ru Guo1,*, Qing-Jiang Pan2,*

    Journal of Renewable Materials, Vol.13, No.5, pp. 885-900, 2025, DOI:10.32604/jrm.2025.02024-0066 - 20 May 2025

    Abstract To achieve the sustainable development and carbon neutral target, biomass chitosan (CS) was used to prepare N,S-doped biochar (NSB) with the assistance of sodium dodecyl benzene sulfonate (SDBS). The synthetic route was developed, which does not require the activation that is frequently-used for active carbon materials. By manipulating their interaction, SDBS was deposited with CS in neutral and basic conditions. Subsequent calcination successfully has access to NSB. It features with hierarchical porous structure and abundant functional groups. The dually-doped NSB bears excellent adsorption performance towards chlortetracycline (CTC). The adsorption capacity reaches 101.3 mg g−1 within 4 More >

  • Open Access

    ARTICLE

    Robust Alzheimer’s Patient Detection and Tracking for Room Entry Monitoring Using YOLOv8 and Cross Product Analysis

    Praveen Kumar Sekharamantry1,2,*, Farid Melgani1, Roberto Delfiore3, Stefano Lusardi3

    CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 4215-4238, 2025, DOI:10.32604/cmc.2025.062686 - 19 May 2025

    Abstract Recent advances in computer vision and artificial intelligence (AI) have made real-time people counting systems extremely reliable, with experts in crowd control, occupancy supervision, and security. To improve the accuracy of people counting at entry and exit points, the current study proposes a deep learning model that combines You Only Look Once (YOLOv8) for object detection, ByteTrack for multi-object tracking, and a unique method for vector-based movement analysis. The system determines if a person has entered or exited by analyzing their movement concerning a predetermined boundary line. Two different logical strategies are used to record… More >

  • Open Access

    ARTICLE

    Bioinformatics and In-Silico Findings Reveal Candidate Genes for Tetralogy of Fallot via Integrative Multi-Omics Data

    Jiawei Shi1,2,3,#, Zhen Wang1,2,3,#, Ying Bai1,2,3, Shiying Li1,2,3, Xin Zhang1,2,3, Tianshu Liu1,2,3, Liu Hong1,2,3, Li Cui1,2,3, Yi Zhang1,2,3, Jing Ma1,2,3, Juanjuan Liu1,2,3, Jing Zhang1,2,3, Haiyan Cao1,2,3,*, Jing Wang1,2,3,*

    Congenital Heart Disease, Vol.20, No.2, pp. 213-229, 2025, DOI:10.32604/chd.2025.064950 - 30 April 2025

    Abstract Background: Tetralogy of Fallot (TOF), the predominant cyanotic congenital heart defect, arises from multifactorial gene-environment interactions disrupting cardiac developmental networks. This study investigated TOF-specific transcriptional alterations and identified high-confidence candidate genes. Methods: Based on GSE36761 transcriptome data, a weighted gene co-expression network analysis (WGCNA) and protein-protein interaction (PPI) network were conducted to identify TOF-related sub-network and Hub genes. The potential biological functions among these genes were revealed by enrichment analysis. Genetic, epigenetic and transcriptional alteration in the Hub genes were analyzed with leveraged public resources: a methylation dataset (GSE62629) and two single-cell datasets (EGAS00001003996 and GSE126128). Results:More >

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