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  • Open Access

    ARTICLE

    Prospective Cohort Research of Aortic Root Dilatation after Surgical Repair in Adults with Tetralogy of Fallot (TRANSIT)

    Hiroki Nagamine1, Masaru Miura1,*, Jun Maeda1, Takumi Nishiki1, Maasa Sato2, Fumie Takechi3, Shigeru Tateno4, Tomoko Ishizu5, Yumi Shiina6, Ken Kato7, Hiroshi Ono8, Hiroyuki Yamagishi9, Koichiro Niwa6

    Congenital Heart Disease, Vol.19, No.4, pp. 351-362, 2024, DOI:10.32604/chd.2024.051837 - 31 October 2024

    Abstract Background: Aortic root dilatation occurs in adults with tetralogy of Fallot (TOF) after surgical repair, but the longitudinal changes are unclear. The main research aim is to determine the annual dilatation rate of aorta in adults with repaired TOF. Methods: The present, multicentric, prospective cohort study assessed the rate of aortic diameter change in adults aged 20 years or older with TOF, including pulmonary artery atresia, who underwent surgical repair. Clinical data, focusing on echocardiograms, were collected at three-year intervals from seven hospitals. Results: In total, 104 patients (58 males; median age: 29 years) were enrolled.… More > Graphic Abstract

    Prospective Cohort Research of Aortic Root Dilatation after Surgical Repair in Adults with Tetralogy of Fallot (TRANSIT)

  • Open Access

    ARTICLE

    Arbuscular Mycorrhizal Fungi Improve Drought Tolerance of Quinoa Grown in Compost-Amended Soils by Altering Primary and Secondary Metabolite Levels

    Wissal Benaffari1,2,3, Fatima-Ezzahra Soussani1,2,4, Abderrahim Boutasknit1,2,5, Salma Toubali1,2,3, Abir Ben Hassine3, Hala Ben Ahmed3, Rachid Lahlali7,*, Abdelilah Meddich1,2,6,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2285-2302, 2024, DOI:10.32604/phyton.2024.055052 - 30 September 2024

    Abstract Quinoa (Chenopodium quinoa) has recently gained popularity as a pseudo-cereal cultivated in various countries due to the nutritional and antioxidant benefits of its seeds, and its capacity to persist in water-stressed environments. Our study aimed to assess the effects of native arbuscular mycorrhizal fungi (AMF) and local organic amendments on the metabolic responses and antioxidant activity of quinoa seeds under water-stressed conditions. To this end, quinoa plants were grown in soils inoculated with an indigenous mycorrhizal consortium AMF and amended with two types of compost from horse manure (HM) and green waste (GW) under two water… More >

  • Open Access

    ARTICLE

    Three New Hydroxytetradecenals from Amomum tsao-ko with Protein Tyrosine Phosphatase 1B and Glycogen Phosphorylase Inhibitory Activity

    Xiaolu Qin1,3, Xinyu Li1,3, Yi Yang2, Mei Huang2, Shengli Wu1, Pianchou Gongpan1, Lianzhang Wu2, Juncai He2, Changan Geng1,3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 875-883, 2024, DOI:10.32604/phyton.2024.048192 - 28 May 2024

    Abstract The fruits of Amomum tsao-ko (Cao-Guo) were documented in Chinese Pharmacopoeia for the treatment of abdominal pain, vomiting, and plague. In our previous study, a series of diarylheptanes and flavonoids with α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activity have been reported from the middle-polarity part of A. tsao-ko, whereas the antidiabetic potency of the low-polarity constituents is still unclear. In this study, three new hydroxytetradecenals, (2E, 4E, 8Z, 11Z)-6R-hydroxytetradeca-2,4,8,11-tetraenal (1), (2E, 4E, 8Z)-6R-hydroxytetradeca-2,4,8-trienal (2) and (2E, 4E)-6R-hydroxytetradeca-2,4-dienal (3) were obtained from the volatile oils of A. tsao-ko. The structures of compounds 1–3 were determined using spectroscopic data involving 1D and 2D nuclear magnetic More >

  • Open Access

    ARTICLE

    Effect of Tetramethylurea (TMU) on Polysulfone Membrane Performance for Atrazine-containing Wastewater Treatment

    NIKITA GUPTA, SARITA KALLA, Z.V.P. MURTHY*

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 317-328, 2023, DOI:10.32381/JPM.2023.40.3-4.12

    Abstract Tetramethylurea (TMU) is a good solvent for organic substances and has received little attention as compared to other solvents. The TMU is a polar solution and is one of the molecules with an amphiphilic character. In the present work, an attempt has been made to use TMU as an additive in the preparation of nanofiltration membranes to improve the hydrophilicity of the membrane. The polysulfone membrane has been modified by incorporating different concentrations of TMU (0, 0.5, and 1 wt.%) in order to check the rejection of atrazine in water. This study aim is to More >

  • Open Access

    ARTICLE

    Single-Cell RNA Sequencing Reveals Potential for Endothelial-to-Mesenchymal Transition in Tetralogy of Fallot

    Aisa Zulibiya1,2,#, Jing Wen3,#, Huiqing Yu3,#, Xiaoming Chen3, Lei Xu3, Xiao Ma1,2, Baojian Zhang1,2,*

    Congenital Heart Disease, Vol.18, No.6, pp. 611-625, 2023, DOI:10.32604/chd.2023.047689 - 19 January 2024

    Abstract Background: Tetralogy of Fallot (TOF) is a very common cyanotic congenital heart disease. Endothelial-to-mesenchymal transition (EndoMT) is recognized as a physiological mechanism involved in embryonic heart development and endothelial formation. However, there is still a gap in the reports related to the mechanism of EndoMT development in TOF. Methods: First, transcriptomic data of single cell nuclei of TOF and Donor were obtained based on the Gene Expression Omnibus (GEO) database, and the data were normalized and clustered by dimensionality reduction using the Seurat package. Subsequently, differentially expressed genes (DEGs) between TOF and Donor were screened… More >

  • Open Access

    CASE REPORT

    Pulmonary Hypertension Crisis in Patient with Tetralogy of Fallot and Mixed Total Anomalous Pulmonary Vein Connection after the Primary Correction: A Rare Case Report

    Dian Kesumarini1,2, Yunita Widyastuti3, Cindy Elfira Boom1, Lucia Kris Dinarti4,*

    Congenital Heart Disease, Vol.18, No.6, pp. 671-678, 2023, DOI:10.32604/chd.2023.044746 - 19 January 2024

    Abstract Tetralogy of Fallot (TOF) with total anomalous pulmonary vein connections (TAPVC) is a rare type of complex congenital heart disease among all TOF cases. Co-presentation of major aortopulmonary collateral arteries (MAPCAs) compensates for the lack of central pulmonary blood flow and decreases the severity of right-to-left shunting in TOF. We present a case of a 2-year-old child with complex diagnoses of TOF, TAPVC, a large secundum atrial septal defect (ASD), and intraoperatively identified MAPCAs. She underwent surgery to repair the TAPVC, valve-sparing reconstruction of the right ventricular outflow tract, interventricular defect closure, and the creation… More >

  • Open Access

    ARTICLE

    Comparative Analysis of the Transcriptome and Metabolome in Leaves of Diploid and Tetraploid Fagopyrum tataricum

    Xiaodong Shi1,*, Yue Qi1, Liangzhu Lin1, Jia Wang1, Xiaobo Qin2, Bei Niu3,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.11, pp. 3149-3162, 2023, DOI:10.32604/phyton.2023.027324 - 24 October 2023

    Abstract Tartary buckwheat (Fagopyrum tataricum) is a dual-purpose medicinal and food crop grown for its high contents of functional compounds and abundant nutrients. Although studies have shown the differences of total flavonoid content in Tartary buckwheat at different ploidy levels, the composition of flavonoid and its regulatory mechanisms are largely unknown. In this study, the leaf metabolome and transcriptome of diploid and tetraploid accessions of Tartary buckwheat were analyzed to gain insight into the impact of polyploidization on comparative secondary metabolite composition and molecular regulatory mechanism. Based on a widely targeted metabolomics analysis, a total of 792… More >

  • Open Access

    PROCEEDINGS

    Nonlinear Dynamics of a Flexible Tether-Net System for Space Debris Capture

    Weicheng Huang1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.09017

    Abstract Here, a flexible tether-net system is applied to capture the space debris and a numerical framework is established to explore its nonlinear dynamic behaviors, which comprises four principal phases: folding, spreading, contacting, and closing [1]. Based on the discretization of the whole structure into multiple nodes and connected edges, elastic force vectors and associated Jacobian matrix are derived analytically to solve a series of equations of motion. With a fully implicit method applied to analyze the nonlinear dynamics of a slender rod network, the involved mechanical responses are investigated numerically accounting for the interactions. Contact… More >

  • Open Access

    ARTICLE

    Preliminary Study on the Treatment Efficiency of Pasteurized Lime Thermal Alkaline Hydrolysis for Excess Activated Sludge and Reduction of Tetracycline Resistance Genes

    Maoxia Chen1,2,*, Qixuan Zhou1, Jiayue Zhang1, Jiaoyang Li1, Wei Zhang1, Huan Liu1

    Journal of Renewable Materials, Vol.11, No.10, pp. 3711-3723, 2023, DOI:10.32604/jrm.2023.027826 - 10 August 2023

    Abstract Thermal alkaline hydrolysis is a common pretreatment method for the utilization of excess activated sludge (EAS). Owing to strict environment laws and need for better energy utilization, new methods were developed in this study to improve the efficiency of pretreatment method. Direct thermal hydrolysis (TH), pasteurized thermal hydrolysis (PTH), and alkaline pasteurized thermal hydrolysis (PTH + CaO and PTH + NaOH) methods were used to treat EAS. Each method was compared and analyzed in terms of dissolution in ammonium nitrogen (NH4 + -N) and soluble COD (SCOD) in EAS. Furthermore, the removal of tetracycline resistance genes… More >

  • Open Access

    ARTICLE

    New Nano Polymer Materials for Composite Exterior-Wall Coatings

    Yue Yu*

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.10, pp. 2681-2694, 2023, DOI:10.32604/fdmp.2023.028250 - 25 June 2023

    Abstract A triethylenetetramine epoxy mixture was synthesized through the reaction of a low-molecular-weight liquid epoxy resin with triethylenetetramine (TETA). Then triethyltetramine (TETA) was injected dropwise into a propylene glycol methyl ether (PM) solution for chain extension reaction. A hydrophilic and flexible polyether segment was introduced into the hardener molecule. The effects of TETA/DGEPG, reaction temperature and reaction time on the epoxy conversion of polyethylene glycol diglycidyl ether (DGEPG) were studied. In addition, several alternate strategies to add epoxy resin to the high-speed dispersion machine and synthesize MEA DGEBA adduct (without catalyst and with bisphenol A diglycidyl More >

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