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  • Open Access


    DDG1 and G Protein α Subunit RGA1 Interaction Regulates Plant Height and Senescence in Rice (Oryza sativa)

    Xi Liu1,2,#,*, Chuxuan Zhao2,#, Di Wang3,#, Gen Pan4, Xiaonan Ji2, Su Gao2, Tanxiao Du2, Yating Feng2, Wenjing Chen2

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 2051-2064, 2023, DOI:10.32604/phyton.2023.028196

    Abstract Many studies have already shown that dwarfism and moderate delayed leaf senescence positively impact rice yield, but the underlying molecular mechanism of dwarfism and leaf senescence remains largely unknown. Here, using map-based cloning, we identified an allele of DEP2, DDG1, which controls plant height and leaf senescence in rice. The ddg1 mutant displayed dwarfism, short panicles, and delayed leaf senescence. Compared with the wild-type, ddg1 was insensitive to exogenous gibberellins (GA) and brassinolide (BR). DDG1 is expressed in various organs, especially in stems and panicles. Yeast two-hybrid assay, bimolecular fluorescent complementation and luciferase complementation image assay showed that DDG1 interacts… More >

  • Open Access


    An AYA with Cancer Confronted with the Grief of a Peer: an Interpretative Phenomenological Analysis

    La confrontation au deuil d’un pair chez une AJA atteinte de cancer. Une analyse phénoménologique interprétative

    J. Phan, V. Laurence, P. Marec-Berard, C. Cordero, C. Riberon, C. Flahault

    Psycho-Oncologie, Vol.16, No.2, pp. 243-252, 2022, DOI:10.3166/pson-2022-0197

    Abstract Aims: Adolescents and Young Adults (AYAs) with cancer facing the loss of another AYA with cancer may face a “triple task”: the process of adolescence, psychological adjustment to cancer, and the bereavement process of a sick peer. The aim of this study was to explore the processes underlying the loss of a sick peer in AYAs with cancer.
    Procedure: A single interview was submitted to an Interpretative Phenomenological Analysis (IPA), designed to understand the system of meanings attached to a subjective and intimate phenomenon such as bereavement.
    Results: Six major themes emerge from the IPA: the life course; the care… More >

  • Open Access


    Long-term Follow-up Consultations for Adult Survivors of Childhood Cancer: Traumatic Experiences and Narrative Process. Stories afterwards

    Consultations de suivi à long terme d’adultes guéris d’un cancer survenu dans l’enfance : vécus traumatiques et travail de narration. Récits dans l’après-coup de la maladie

    M. Laget, L. Fasse, B. Fresneau, E. Ricadat, S. Rivollet

    Psycho-Oncologie, Vol.16, No.2, pp. 267-272, 2022, DOI:10.3166/pson-2022-0190

    Abstract As part of the medical follow-up program for adult survivors of childhood cancer at the Institut Gustave Roussy (Villejuif, France), a psychological consultation is offered. This article is based on 198 interviews with patients between the ages of 18 and 67 who were diagnosed between the ages of 0 and 24. These meetings give voice to the subjectivity of cancer and recovery, revealing the traces of this experience afterwards. The issues at stake in the narrative activity initiated in the context of this consultation, and which may continue beyond, are approached from a metapsychological perspective.

    Dans le cadre… More >

  • Open Access


    Analyser la structure de dispositifs de mise à disposition de données géographiques

    Application aux enjeux de suivi et de gestion du trait de côte en France

    Johan Desbonnet1 , Françoise Gourmelon1, Christophe Claramunt2

    Revue Internationale de Géomatique, Vol.29, No.1, pp. 57-80, 2019, DOI:10.3166/rig.2019.00079

    Abstract In the context of shoreline management and monitoring issues, inferring information and knowledge from the Web are considered as a crucial issue. However, Spatial Data Infrastructures promoters’ strategies and content are still unknown. This article presents a methodological approach to study the technical possibilities of access to the digital geographic information on online platforms often used for shoreline management and monitoring in France. Geographical data access on such platforms is granted by the presence of hyperlinks and Geospatial Web services. The analysis of this structural components (hyperlinks and Web services) shows a disparate situation for the access to geographical information.… More >

  • Open Access


    Objets et relations spatiales composites et prise en compte du vague pour interpréter un référencement spatial indirect

    Mattia Bunel, Ana-Maria Olteanu-Raimond, Cécile Duchêne

    Revue Internationale de Géomatique, Vol.29, No.1, pp. 81-106, 2019, DOI:10.3166/rig.2019.00075

    Abstract This paper proposes a methodology for transforming a position description expressed relatively in an indirect spatial reference system into an absolute position in a direct spatial reference system. This problem requires (1) to formalize the relative location elements, here in the form of a triplet model, which is used as a basis for the transformation from relative to absolute position, and (2) to investigate how the imperfection of the natural language can be taken into account in the modeling process. We propose to use fuzzy spatial objects and we will compare their implementations to identify the most appropriate approach to… More >

  • Open Access


    Utilisation du modèle PAP/CAR et du SIG pour un zonage du risque d’érosion hydrique

    Exemple du bassin versant de Tessa (Tunisie)

    Nassira Zouaoui, Radhia Mansour, Abdessalem El Ghali

    Revue Internationale de Géomatique, Vol.29, No.3, pp. 361-380, 2019, DOI:10.3166/rig.2020.00096

    Abstract In the humid Mediterranean regions, particularly the NW of Tunisia, the Tessa catchment area is characterized by torrential and irregular rains, combined with significant deforestation, which causes severe erosion that carries away and redistributes the soil. The process of water erosion is very frequent and changes its dynamic aspect according to the evolution and spatial variation of the lithological nature of rocks, the geomorphology of landscapes, the geometry of watersheds and their bioclimatic situation. In this study, an appropriate methodological flowchart was followed by applying the PAP/RAC erosion mapping method, which is based on the principle of weighting the main… More >

  • Open Access


    L’évolution de l’occupation du sol et des inégalités environnementales dans la ville minière de Métlaoui par le biais d’un SIG-AMC

    Bilel Salhi1 , Mohsen Dhieb2,3, Yamna Djellouli4

    Revue Internationale de Géomatique, Vol.29, No.3, pp. 381-399, 2019, DOI:10.3166/rig.2020.00094

    Abstract The city of Métlaoui is the most important urban core in Gafsa Mining Basin (BMG) in southwestern Tunisia. Like other BMG cities, it is characterized by a single industrial activity of phosphate enrichment and observes a spatial activity between the “European village” favorized to a certain term and the peripheral cities disadvantaged. Today, this dichotomy is not decreasing; on the contrary, the research reveals real signs of accentuation of this socio- spatial segregation inherited from colonial and post-colonial periods, and the environmental vicissitudes confirm the territorial iniquity. The research methodology has used for the social-spatial aspect heterogeneous data sources and… More >

  • Open Access


    Targeting triple-negative breast cancer: A clinical perspective


    Oncology Research, Vol.31, No.3, pp. 221-238, 2023, DOI:10.32604/or.2023.028525

    Abstract Triple-negative breast cancer (TNBC) is a disease with often an aggressive course and a poor prognosis compared to other subtypes of breast cancer. TNBC accounts for approximately 10%–15% of all diagnosed breast cancer cases and represents a high unmet need in the field. Up to just a few years ago, chemotherapy was the only systemic treatment option for this subtype (1). To date, TNBC is considered a heterogeneous disease. One of the existing classifications is based on the analysis of mRNA expression in 587 TNBC cases, in which Lehman et al. proposed six subtypes of TNBC as follows: two basal-like… More > Graphic Abstract

    Targeting triple-negative breast cancer: A clinical perspective

  • Open Access


    Apolipoprotein C1 promotes tumor progression in gastric cancer


    Oncology Research, Vol.31, No.3, pp. 287-297, 2023, DOI:10.32604/or.2023.028124

    Abstract Background: Gastric cancer (GC) is a malignancy with the worst prognosis that seriously threatens human health, especially in East Asia. Apolipoprotein C1 (apoc1) belongs to the apolipoprotein family. In addition, apoc1 has been associated with various tumors. However, its role in GC remains unclear. Methods: Firstly, we quantified its expression in GC and adjacent tumor tissues, using The Cancer Genome Atlas (TCGA). Next, we assessed cell invasion and migration abilities. Finally, we revealed the role of apoc1 in the tumor microenvironment (TME), immune cell infiltration and drug sensitivity. Results: Firstly, in TCGA database, it has been shown that elevated expression… More >

  • Open Access


    Calcyclin-binding protein contributes to cholangiocarcinoma progression by inhibiting ubiquitination of MCM2


    Oncology Research, Vol.31, No.3, pp. 317-331, 2023, DOI:10.32604/or.2023.028418

    Abstract Background: Cholangiocarcinoma (CCA) represents the epithelial cell cancer with high aggressiveness whose five-year survival rate is poor with standard treatment. Calcyclin-binding protein (CACYBP) shows aberrant expression within several malignant tumors, but the role of CACYBP in CCA remains unknown. Methods: Immunohistochemical (IHC) analysis was used to identify CACYBP overexpression in clinical samples of CCA patients. Moreover, its correlation with clinical outcome was revealed. Furthermore, CACYBP’s effect on CCA cell growth and invasion was investigated in vitro and in vivo using loss-of-function experiments. Results: CACYBP showed up-regulation in CCA, which predicts the dismal prognostic outcome. CACYBP had an important effect on… More >

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